Biochemistry
Dna Replication And Repair
Compiled By Simon Mwangi
Edition: 2024/25
, Science | Biochemistry I of VII pages
1. Replication of DNA occurs in a ____-_____ manner
semi-conservative
2. ______ replication of DNA is a model where each DNA strand serves as a template for DNA synthesis, but
Conservative
note: if this model was correct, there would be no DNA molecules composed of parental an daughter strands
3. Each new DNA molecule consists of an old strand (the template) and a new strand in semi-conservative
true
4. Bacteria have single chromosomes which are circular and possess a unique replication origin. True or false?
true
5. Eukaryotic chromosomes have how many separate origins of replication per chromosome?
1000-2000
6. Bidirectional replication (two replication forks proceeding in opposite directions) does not occur in DNA.
false; it does
7. DNA replication proceeds only in the ___ > ____ direction
5>3
8. DNA replication is initiated from pre-existing ____ (short section of RNA which is complementary to the
primers
9. DNA synthesis proceeds from discreet sites meaning it must unravel two parental DNA strands at particular
template
10. In this strand, replication is continuous
leading strand
11. in this strand, replication proceeds from multiple primers and results in forming short DNA sequences
lagging strand
12. ____ problems must be overcome in DNA replication. Both prokaryotic and eukaryotic DNAs exist not as
molecules with free ends but rather as closed-loop molecules. ____ of the DNA molecule during replication
topological; supercoiling
deoxyribonucleic triphosphates
13. All DNA polymerases require both a template and a primer. True or false?
true
14. During DNA replication in both prokaryotic and eukaryotic cells, both of the strands of the parent DNA
template; primer
15. In regards to prokaryotic replication, RNApolymerase (primase) is necessary for what?
the synthesis o the RNA primers required for DNA replication
Biochemistry 2024/25 Edition
Dna Replication And Repair
Compiled By Simon Mwangi
Edition: 2024/25
, Science | Biochemistry I of VII pages
1. Replication of DNA occurs in a ____-_____ manner
semi-conservative
2. ______ replication of DNA is a model where each DNA strand serves as a template for DNA synthesis, but
Conservative
note: if this model was correct, there would be no DNA molecules composed of parental an daughter strands
3. Each new DNA molecule consists of an old strand (the template) and a new strand in semi-conservative
true
4. Bacteria have single chromosomes which are circular and possess a unique replication origin. True or false?
true
5. Eukaryotic chromosomes have how many separate origins of replication per chromosome?
1000-2000
6. Bidirectional replication (two replication forks proceeding in opposite directions) does not occur in DNA.
false; it does
7. DNA replication proceeds only in the ___ > ____ direction
5>3
8. DNA replication is initiated from pre-existing ____ (short section of RNA which is complementary to the
primers
9. DNA synthesis proceeds from discreet sites meaning it must unravel two parental DNA strands at particular
template
10. In this strand, replication is continuous
leading strand
11. in this strand, replication proceeds from multiple primers and results in forming short DNA sequences
lagging strand
12. ____ problems must be overcome in DNA replication. Both prokaryotic and eukaryotic DNAs exist not as
molecules with free ends but rather as closed-loop molecules. ____ of the DNA molecule during replication
topological; supercoiling
deoxyribonucleic triphosphates
13. All DNA polymerases require both a template and a primer. True or false?
true
14. During DNA replication in both prokaryotic and eukaryotic cells, both of the strands of the parent DNA
template; primer
15. In regards to prokaryotic replication, RNApolymerase (primase) is necessary for what?
the synthesis o the RNA primers required for DNA replication
Biochemistry 2024/25 Edition
