UTMB ADVANCED PATHOPHYSIOLOGY
5355 Exam 3 questions with answers
Biogenic Amine Theory linked to depression - ** VERIFIED ANSWERS🔰 ✔✔Deficiency of
neurotransmitters in brain of norepinephrine, dopamine, and/or serotonin. Particularly, a
decrease in receptor binding with serotonin.
Neurotransmitter Receptor Hypothesis linked to depression - ** VERIFIED ANSWERS🔰
✔✔A deficiency of monoamine neurotransmitters at neuronal synapses.
Antidepressants increase - ** VERIFIED ANSWERS🔰 ✔✔Neuronal synaptic levels of
monoamine neurotransmitters.
if you have more receptors than neurotransmitters - ** VERIFIED ANSWERS🔰
✔✔Neurotransmitters do not have time to re-charge thus, they do not function properly.
Hypothalamic-Pituitary-Adrenal (HPA) System Dysregulation - ** VERIFIED ANSWERS🔰
✔✔HPA system dysregulation with excessive glucocorticoid secretion is found in a large
percentage of people suffering from major depression.
Patho of Alzheimer's includes - plaque formation, presence of --, with decreased levels of - -
** VERIFIED ANSWERS🔰 ✔✔Amyloid B, neurofibrillary tangles, acetylcholine these
disrupt impulse transmission
neurofibrillary tangles - ** VERIFIED ANSWERS🔰 ✔✔are a deformation of the structure
that carries nutrients to neurons of the brain.
,Decreased levels of choline acetyl transferase and acetylcholine is associated with - **
VERIFIED ANSWERS🔰 ✔✔Memory loss
Most common cause of dementia - ** VERIFIED ANSWERS🔰 ✔✔Alzheimer's disease fatal
5-10 years
Characteristics of Alzheimer's - ** VERIFIED ANSWERS🔰 ✔✔Loss of memory, language ,
inability to learn new things, dysfunction, delusions, cannot perform ADLs, majorly effects
social life
Parkinson's Disease is - ** VERIFIED ANSWERS🔰 ✔✔Chronic motor progressive neuro-
degenerative known as a shaking palsy
Parkinson's disease is associated with - ** VERIFIED ANSWERS🔰 ✔✔basal ganglia
dysfunction and atrophy of neurons in the substantia nigra that produce dopamine;
Characteristics of Parkinson's disease - ** VERIFIED ANSWERS🔰 ✔✔Tremors at rest,
rigidity, bradykinesia, muscular rigidity and postural abnormalities.
2 Main Categories of CVA - ** VERIFIED ANSWERS🔰 ✔✔Hemorrhagic and Ischemic
Hemorrhagic CVA - ** VERIFIED ANSWERS🔰 ✔✔Blood produces inflammatory
reaction, swelling, displaces brain tissue and increases ICP
2 types of hemorrhagic stroke - ** VERIFIED ANSWERS🔰 ✔✔Intracerebral and
subarachnoid
Intracerebral Hemorrhage - ** VERIFIED ANSWERS🔰 ✔✔Blood vessel leaks directly into
brain tissue
, Subarachnoid hemorrhage - ** VERIFIED ANSWERS🔰 ✔✔Bleeding into the
subarachnoid space, caused by trauma, aneurysm rupture presents as "worst headache of
life". surgical emergency
Ischemic CVA - ** VERIFIED ANSWERS🔰 ✔✔reduction in cerebral blood flow results in
hypoxia and irreversible cell death with associated cerebral edema
3 types of ischemic CVA - ** VERIFIED ANSWERS🔰 ✔✔thrombotic, embolic,
hypercoagulable states.
Thrombotic - ** VERIFIED ANSWERS🔰 ✔✔caused by atherosclerosis blocking vessels.
obstruction of blood vessel due to localized occlusive process
Embolic - ** VERIFIED ANSWERS🔰 ✔✔caused by blood clot, fat or air embolus traveling
from distant site to brain
Hypercoaguable state - ** VERIFIED ANSWERS🔰 ✔✔conditions such as sickle cell
disease, polycythemia causing blood clot to form and obstruct vessel
Multiple sclerosis - ** VERIFIED ANSWERS🔰 ✔✔chronic, inflammatory autoimmune
demyelinating disease of the CNS. : patho includes CNS demyelination thought to be caused
by an immune reaction
Acetylcholine - ** VERIFIED ANSWERS🔰 ✔✔excitatory or inhibitory, enables muscle
action, learning, memory- involved in memory impairment in Alzheimer's disease
Norepinephrine - ** VERIFIED ANSWERS🔰 ✔✔Helps control alertness and arousal.
Under supply can depress mood.
5355 Exam 3 questions with answers
Biogenic Amine Theory linked to depression - ** VERIFIED ANSWERS🔰 ✔✔Deficiency of
neurotransmitters in brain of norepinephrine, dopamine, and/or serotonin. Particularly, a
decrease in receptor binding with serotonin.
Neurotransmitter Receptor Hypothesis linked to depression - ** VERIFIED ANSWERS🔰
✔✔A deficiency of monoamine neurotransmitters at neuronal synapses.
Antidepressants increase - ** VERIFIED ANSWERS🔰 ✔✔Neuronal synaptic levels of
monoamine neurotransmitters.
if you have more receptors than neurotransmitters - ** VERIFIED ANSWERS🔰
✔✔Neurotransmitters do not have time to re-charge thus, they do not function properly.
Hypothalamic-Pituitary-Adrenal (HPA) System Dysregulation - ** VERIFIED ANSWERS🔰
✔✔HPA system dysregulation with excessive glucocorticoid secretion is found in a large
percentage of people suffering from major depression.
Patho of Alzheimer's includes - plaque formation, presence of --, with decreased levels of - -
** VERIFIED ANSWERS🔰 ✔✔Amyloid B, neurofibrillary tangles, acetylcholine these
disrupt impulse transmission
neurofibrillary tangles - ** VERIFIED ANSWERS🔰 ✔✔are a deformation of the structure
that carries nutrients to neurons of the brain.
,Decreased levels of choline acetyl transferase and acetylcholine is associated with - **
VERIFIED ANSWERS🔰 ✔✔Memory loss
Most common cause of dementia - ** VERIFIED ANSWERS🔰 ✔✔Alzheimer's disease fatal
5-10 years
Characteristics of Alzheimer's - ** VERIFIED ANSWERS🔰 ✔✔Loss of memory, language ,
inability to learn new things, dysfunction, delusions, cannot perform ADLs, majorly effects
social life
Parkinson's Disease is - ** VERIFIED ANSWERS🔰 ✔✔Chronic motor progressive neuro-
degenerative known as a shaking palsy
Parkinson's disease is associated with - ** VERIFIED ANSWERS🔰 ✔✔basal ganglia
dysfunction and atrophy of neurons in the substantia nigra that produce dopamine;
Characteristics of Parkinson's disease - ** VERIFIED ANSWERS🔰 ✔✔Tremors at rest,
rigidity, bradykinesia, muscular rigidity and postural abnormalities.
2 Main Categories of CVA - ** VERIFIED ANSWERS🔰 ✔✔Hemorrhagic and Ischemic
Hemorrhagic CVA - ** VERIFIED ANSWERS🔰 ✔✔Blood produces inflammatory
reaction, swelling, displaces brain tissue and increases ICP
2 types of hemorrhagic stroke - ** VERIFIED ANSWERS🔰 ✔✔Intracerebral and
subarachnoid
Intracerebral Hemorrhage - ** VERIFIED ANSWERS🔰 ✔✔Blood vessel leaks directly into
brain tissue
, Subarachnoid hemorrhage - ** VERIFIED ANSWERS🔰 ✔✔Bleeding into the
subarachnoid space, caused by trauma, aneurysm rupture presents as "worst headache of
life". surgical emergency
Ischemic CVA - ** VERIFIED ANSWERS🔰 ✔✔reduction in cerebral blood flow results in
hypoxia and irreversible cell death with associated cerebral edema
3 types of ischemic CVA - ** VERIFIED ANSWERS🔰 ✔✔thrombotic, embolic,
hypercoagulable states.
Thrombotic - ** VERIFIED ANSWERS🔰 ✔✔caused by atherosclerosis blocking vessels.
obstruction of blood vessel due to localized occlusive process
Embolic - ** VERIFIED ANSWERS🔰 ✔✔caused by blood clot, fat or air embolus traveling
from distant site to brain
Hypercoaguable state - ** VERIFIED ANSWERS🔰 ✔✔conditions such as sickle cell
disease, polycythemia causing blood clot to form and obstruct vessel
Multiple sclerosis - ** VERIFIED ANSWERS🔰 ✔✔chronic, inflammatory autoimmune
demyelinating disease of the CNS. : patho includes CNS demyelination thought to be caused
by an immune reaction
Acetylcholine - ** VERIFIED ANSWERS🔰 ✔✔excitatory or inhibitory, enables muscle
action, learning, memory- involved in memory impairment in Alzheimer's disease
Norepinephrine - ** VERIFIED ANSWERS🔰 ✔✔Helps control alertness and arousal.
Under supply can depress mood.
