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OCCTH 585 NEURO QUESTIONS
LATEST 2024-2025 AND CORRECT
DETAILED ANSWERS (VERIFIED
ANSWERS) |ALREADY GRADED A+
Information flows through neurons from ____ to ____ in the neuron
ANS:
✓ dendrite; axon
_____ bring a cell to threshold while _____ bring a cell further from threshold
ANS:
✓ EPSPs; IPSPs
What 3 main things is neuroplasticity capable of?
ANS:
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✓ - changing the properties of neurotransmission
✓ - changes in cell properties
✓ - structural/ anatomical changes of cells
How does neuroplasticity change the properties of neurotransmission? (2)
ANS:
✓ - change in transmitter size
✓ - change in PSP size or shape
How does neuroplasticity change the properties of cells? (3)
ANS:
✓ - size and shape
✓ - electrical properties (resistance)
✓ - "leakiness" of membrane
What is unmasking?
ANS:
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✓ when an injury, event, or illness eliminates the inputs that a neuron
most commonly responds to (i.e. blue --> blue region of brain), the
neuron will become more responsive to the other inputs on the neuron
(i.e. yellow --> yellow region of brain) and that new representation will
increase; is immediate, involves exposure of pre-existing synapses, and
creates functional changes in the cell
What is dendritic pruning?
ANS:
✓ when dendrites with no active synapses are retracted to reduce the
amount of resources wasted to keep those useless dendrites alive;
changes cellular properties (size and shape) and creates as 'loss of real
estate', decreases energy expenditure
What is collateral sprouting?
ANS:
✓ when neurons sprout new synapses on bare dendrites (either after
pruning of dead synapses or less used working ones) leading the cell to
become more responsive to those new inputs
What can lead to collateral sprouting?
ANS:
✓ more stimulation; higher representation is driven by high rates of APs
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What are the 6 mechanisms of collateral sprouting?
ANS:
✓ - growth of new bits
✓ - requires time
✓ - fill vacancy OR push less used synapses out of the way
✓ - activity dependent
✓ - produces functional changes
Do neurons have to be close to the "free real estate" in order to make new
collaterals? Do they need to already be involved with it?
ANS:
✓ no, the closest ones will usually get there first, but the axons can grow
out 1-2cm to form a connection (any further = stuff in the way, would
take too long and die); no
What signals to other neurons that there is space to form new collaterals and
guides them to it?
ANS:
✓ neurotrophin (released by dendritic spines through APs)
What are chemoattractants?
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