Walden 6630 Psychopharmacology
Midterm Study Guide questions with
complete solutions
Serotonin regulates - VERIFIED ANSWER✔✔-Mood, emotion, feeding, and reproductive behavior
This class of antidepressants binds to presynaptic SERT and inhibits them from reuptake of serotonin to
increase levels in the synaptic cleft to bind with postsysnaptic 5HT2 receptors - VERIFIED ANSWER✔✔-
SSRIs
First line therapy for MDD due to milder side effect profiles - VERIFIED ANSWER✔✔-SSRIs
Six Common SSRIs - VERIFIED ANSWER✔✔-citalopram, escitalopram, fluoxetine, fluvoxamine, sertraline,
paroxetine
Onset of therapeutic benefit from SSRIs - VERIFIED ANSWER✔✔-4-6 weeks
In addition to MDD, SSRIs also treat - VERIFIED ANSWER✔✔-Chronic Anxiety, PTSD, OCD, and eating
disorders (bulimia)
Five Common side effects of SSRIs include - VERIFIED ANSWER✔✔-Anxiety, insomnia, GI distress, sexual
dysfunction (ED), SIADH
Severe side effect of SSRIs in children/adolescents under age 25 years old - VERIFIED ANSWER✔✔-
suicidal ideation
Life threatening adverse effect of SSRIs, especially when used in combination with other serotonergic
drugs (SNRIs, TCAs, MAOIs, etc.) - VERIFIED ANSWER✔✔-Serotonin Syndrome
Walden 6630 Psychopharmacology Midterm Study Guide questions with complete solutions
,Excess accumulation of serotonin resulting in overstimulation of the nervous system - VERIFIED
ANSWER✔✔-Serotonin Syndrome
Seven symptoms of Serotonin Syndrome - VERIFIED ANSWER✔✔-Flushing, hyperthermia, agitation,
muscle rigidity, seizure, coma, HYPERreflexia
The treatment for serotonin syndrome - VERIFIED ANSWER✔✔-Cyproheptadine (5-HT2 receptor
antagonist)
Cyproheptadine treats serotonin syndrome by - VERIFIED ANSWER✔✔-blocking 5-HT2 receptors
(serotonin antagonist)
When SSRIs or SNRIs are stopped abruptly, common symptoms of withdrawal include - VERIFIED
ANSWER✔✔-Irritability, headaches, and insomnia
Medicine specific side effect of citalopram - VERIFIED ANSWER✔✔-Prolonged QT interval (normal=0.4.-
0.44 seconds)
This SSRI is pregnancy category D due to associations with congenital heart defects - VERIFIED
ANSWER✔✔-Paroxetine
All SSRIs but paroxetine (D) are pregnancy category - VERIFIED ANSWER✔✔-C
Three SSRIs that are inhibitors of Cytochrome P450 enzymes - VERIFIED ANSWER✔✔-fluoxetine,
fluvoxamine, and paroxetine
Five common SNRIs include - VERIFIED ANSWER✔✔-duloxetine, venlafaxine, desvenlafaxine,
milnacipran, levomilnacipran
This antidepressant class of medications works by binding to presynaptic SERT and NET to inhibit them
from reuptake of serotonin and norepinephrine to increase their levels in the synaptic cleft - VERIFIED
ANSWER✔✔-SNRIs
Walden 6630 Psychopharmacology Midterm Study Guide questions with complete solutions
, In addition to MDD SNRIs treat - VERIFIED ANSWER✔✔-Anxiety and neuropathic pain (peripheral
neuropathy)
Medication specific indications of duloxetine: - VERIFIED ANSWER✔✔-urinary incontinence and
Fibromyalgia
Medication specific indications of venlafaxine: - VERIFIED ANSWER✔✔-social anxiety, panic disorders,
PTSD, OCD, postmenopausal hot flashes
Six common side effects of SNRIs include: - VERIFIED ANSWER✔✔-Insomnia, nausea, sexual dysfunction,
hypertension, sweating, headaches
Severe side effect of SNRIs in children/adolescents under age 25 years old: - VERIFIED ANSWER✔✔-
suicidal ideation
Life threatening adverse effect of SNRIs, especially when used in combination with other serotonergic
drugs: - VERIFIED ANSWER✔✔-Serotonin Syndrome
This SNRI is an inhibitor of Cytochrome P450 enzymes: - VERIFIED ANSWER✔✔-venlafaxine
This SNRI is hepatotoxic: - VERIFIED ANSWER✔✔-duloxetine
MAOIs increase the levels of: - VERIFIED ANSWER✔✔-Serotonin, Norepinephrine, and Dopamine
Norepinephrine regulates: - VERIFIED ANSWER✔✔-alertness and focus
Dopamine regulates: - VERIFIED ANSWER✔✔-cognitive function, motivation, and awakeness
In the synaptic cleft, Monoamine Oxidase A breaks down: - VERIFIED ANSWER✔✔-Serotonin,
Norepinephrine, and Dopamine
Walden 6630 Psychopharmacology Midterm Study Guide questions with complete solutions
Midterm Study Guide questions with
complete solutions
Serotonin regulates - VERIFIED ANSWER✔✔-Mood, emotion, feeding, and reproductive behavior
This class of antidepressants binds to presynaptic SERT and inhibits them from reuptake of serotonin to
increase levels in the synaptic cleft to bind with postsysnaptic 5HT2 receptors - VERIFIED ANSWER✔✔-
SSRIs
First line therapy for MDD due to milder side effect profiles - VERIFIED ANSWER✔✔-SSRIs
Six Common SSRIs - VERIFIED ANSWER✔✔-citalopram, escitalopram, fluoxetine, fluvoxamine, sertraline,
paroxetine
Onset of therapeutic benefit from SSRIs - VERIFIED ANSWER✔✔-4-6 weeks
In addition to MDD, SSRIs also treat - VERIFIED ANSWER✔✔-Chronic Anxiety, PTSD, OCD, and eating
disorders (bulimia)
Five Common side effects of SSRIs include - VERIFIED ANSWER✔✔-Anxiety, insomnia, GI distress, sexual
dysfunction (ED), SIADH
Severe side effect of SSRIs in children/adolescents under age 25 years old - VERIFIED ANSWER✔✔-
suicidal ideation
Life threatening adverse effect of SSRIs, especially when used in combination with other serotonergic
drugs (SNRIs, TCAs, MAOIs, etc.) - VERIFIED ANSWER✔✔-Serotonin Syndrome
Walden 6630 Psychopharmacology Midterm Study Guide questions with complete solutions
,Excess accumulation of serotonin resulting in overstimulation of the nervous system - VERIFIED
ANSWER✔✔-Serotonin Syndrome
Seven symptoms of Serotonin Syndrome - VERIFIED ANSWER✔✔-Flushing, hyperthermia, agitation,
muscle rigidity, seizure, coma, HYPERreflexia
The treatment for serotonin syndrome - VERIFIED ANSWER✔✔-Cyproheptadine (5-HT2 receptor
antagonist)
Cyproheptadine treats serotonin syndrome by - VERIFIED ANSWER✔✔-blocking 5-HT2 receptors
(serotonin antagonist)
When SSRIs or SNRIs are stopped abruptly, common symptoms of withdrawal include - VERIFIED
ANSWER✔✔-Irritability, headaches, and insomnia
Medicine specific side effect of citalopram - VERIFIED ANSWER✔✔-Prolonged QT interval (normal=0.4.-
0.44 seconds)
This SSRI is pregnancy category D due to associations with congenital heart defects - VERIFIED
ANSWER✔✔-Paroxetine
All SSRIs but paroxetine (D) are pregnancy category - VERIFIED ANSWER✔✔-C
Three SSRIs that are inhibitors of Cytochrome P450 enzymes - VERIFIED ANSWER✔✔-fluoxetine,
fluvoxamine, and paroxetine
Five common SNRIs include - VERIFIED ANSWER✔✔-duloxetine, venlafaxine, desvenlafaxine,
milnacipran, levomilnacipran
This antidepressant class of medications works by binding to presynaptic SERT and NET to inhibit them
from reuptake of serotonin and norepinephrine to increase their levels in the synaptic cleft - VERIFIED
ANSWER✔✔-SNRIs
Walden 6630 Psychopharmacology Midterm Study Guide questions with complete solutions
, In addition to MDD SNRIs treat - VERIFIED ANSWER✔✔-Anxiety and neuropathic pain (peripheral
neuropathy)
Medication specific indications of duloxetine: - VERIFIED ANSWER✔✔-urinary incontinence and
Fibromyalgia
Medication specific indications of venlafaxine: - VERIFIED ANSWER✔✔-social anxiety, panic disorders,
PTSD, OCD, postmenopausal hot flashes
Six common side effects of SNRIs include: - VERIFIED ANSWER✔✔-Insomnia, nausea, sexual dysfunction,
hypertension, sweating, headaches
Severe side effect of SNRIs in children/adolescents under age 25 years old: - VERIFIED ANSWER✔✔-
suicidal ideation
Life threatening adverse effect of SNRIs, especially when used in combination with other serotonergic
drugs: - VERIFIED ANSWER✔✔-Serotonin Syndrome
This SNRI is an inhibitor of Cytochrome P450 enzymes: - VERIFIED ANSWER✔✔-venlafaxine
This SNRI is hepatotoxic: - VERIFIED ANSWER✔✔-duloxetine
MAOIs increase the levels of: - VERIFIED ANSWER✔✔-Serotonin, Norepinephrine, and Dopamine
Norepinephrine regulates: - VERIFIED ANSWER✔✔-alertness and focus
Dopamine regulates: - VERIFIED ANSWER✔✔-cognitive function, motivation, and awakeness
In the synaptic cleft, Monoamine Oxidase A breaks down: - VERIFIED ANSWER✔✔-Serotonin,
Norepinephrine, and Dopamine
Walden 6630 Psychopharmacology Midterm Study Guide questions with complete solutions
