BIOCHEM 4300 NEW EXAM WITH COMPLETE
SOLUTIONS
Consider the reaction: aA + bB ® cC +dD. The reaction Gibbs energy can bewritten as .Q
is called the______ and is equal to____ - ANSWER reaction quotient: ac^c x ad^d/ aA^Ax
ab^b
Delta r G < 0 for a reaction when the __________ predominate. The_________reaction is
spontaneous; ____________formation dominates - ANSWER reactants , forward reaction,
products
Delta r G > 0 for a reaction when the _____________ predominate. The_________reaction is
spontaneous. - ANSWER products, reverse reaction
At equilibrium, the reaction quotient assumes a value called the - ANSWER equilibrium
constant
At the minimum of a plot of G versus composition, D r G = 0, the reaction is___________,
and the rates of the forward and reverse reactions - ANSWER equilibrium, are equal
Knowledge of the equilibrium constant provides insight into the relativespontaneity of
the reaction.If K > 1, the ___________________direction is favored.If K < 1, the
___________________direction is favored. - ANSWER forward , reverse
Consider the following reaction:glycerol + ATP ® glycerol-1-phosphate + ADP + H +a.
The biochemical equilibrium constant, K¢, will be a factor of _____(larger/smaller) than
the thermodynamic equilibrium constant, K. - ANSWER 10^7 , larger
The biological standard Gibbs energy change, DG°¢, will be a _____ kJ mol -1(more/less)
favorable than the thermodynamic standard Gibbs energy change,DG° - ANSWER 39.9,
, more
Consider the following reaction: pyruvate + NADH + H+ ® lactate + NAD +The
biochemical equilibrium constant, K¢, will be a factor of _____ (larger/smaller)than the
thermodynamic equilibrium constant, K.The biological standard Gibbs energy change,
DG°¢, will be a _____ kJ mol -1(more/less) favorable than the thermodynamic standard
Gibbs energy change,DG°.8. Consider the reaction B ® - ANSWER 10^7, smaller, 39.9,
less
A. The energy levels for B andA are indicated in the diagram on the right.The reaction is
exothermic / endothermic.The reaction is enthalpically favorable / unfavorableThe
reaction is entropically favorable / unfavorable/neither9. - ANSWER exothermic,
favorable , neither
Consider the reaction A ® B. The energy levels for B and Aare indicated in the diagram
on the right.The reaction is exothermic / endothermic.The reaction is enthalpically
favorable / unfavorableThe reaction is entropically favorable / unfavorable /neither -
ANSWER endothermic, unfavorable , favorable
hemoglobin - ANSWER loads o2 in lung and unloads o2 in the body
Binding constants that refer to
the population of macrostate are called_________binding constants. - ANSWER
Macroscopic
_____________________describes the ligand binding states of the entire macromolecule. -
ANSWER partion function
myoglobin - ANSWER always carries oxygen
T here+are+two+types+of+macroscopic+binding+constants+-+β i +and+K i .++ +a.+ a.
What+is+the+difference+between+them?+
b. What+is+the+mathematical+relationship+between+them? - ANSWER a. β I$
SOLUTIONS
Consider the reaction: aA + bB ® cC +dD. The reaction Gibbs energy can bewritten as .Q
is called the______ and is equal to____ - ANSWER reaction quotient: ac^c x ad^d/ aA^Ax
ab^b
Delta r G < 0 for a reaction when the __________ predominate. The_________reaction is
spontaneous; ____________formation dominates - ANSWER reactants , forward reaction,
products
Delta r G > 0 for a reaction when the _____________ predominate. The_________reaction is
spontaneous. - ANSWER products, reverse reaction
At equilibrium, the reaction quotient assumes a value called the - ANSWER equilibrium
constant
At the minimum of a plot of G versus composition, D r G = 0, the reaction is___________,
and the rates of the forward and reverse reactions - ANSWER equilibrium, are equal
Knowledge of the equilibrium constant provides insight into the relativespontaneity of
the reaction.If K > 1, the ___________________direction is favored.If K < 1, the
___________________direction is favored. - ANSWER forward , reverse
Consider the following reaction:glycerol + ATP ® glycerol-1-phosphate + ADP + H +a.
The biochemical equilibrium constant, K¢, will be a factor of _____(larger/smaller) than
the thermodynamic equilibrium constant, K. - ANSWER 10^7 , larger
The biological standard Gibbs energy change, DG°¢, will be a _____ kJ mol -1(more/less)
favorable than the thermodynamic standard Gibbs energy change,DG° - ANSWER 39.9,
, more
Consider the following reaction: pyruvate + NADH + H+ ® lactate + NAD +The
biochemical equilibrium constant, K¢, will be a factor of _____ (larger/smaller)than the
thermodynamic equilibrium constant, K.The biological standard Gibbs energy change,
DG°¢, will be a _____ kJ mol -1(more/less) favorable than the thermodynamic standard
Gibbs energy change,DG°.8. Consider the reaction B ® - ANSWER 10^7, smaller, 39.9,
less
A. The energy levels for B andA are indicated in the diagram on the right.The reaction is
exothermic / endothermic.The reaction is enthalpically favorable / unfavorableThe
reaction is entropically favorable / unfavorable/neither9. - ANSWER exothermic,
favorable , neither
Consider the reaction A ® B. The energy levels for B and Aare indicated in the diagram
on the right.The reaction is exothermic / endothermic.The reaction is enthalpically
favorable / unfavorableThe reaction is entropically favorable / unfavorable /neither -
ANSWER endothermic, unfavorable , favorable
hemoglobin - ANSWER loads o2 in lung and unloads o2 in the body
Binding constants that refer to
the population of macrostate are called_________binding constants. - ANSWER
Macroscopic
_____________________describes the ligand binding states of the entire macromolecule. -
ANSWER partion function
myoglobin - ANSWER always carries oxygen
T here+are+two+types+of+macroscopic+binding+constants+-+β i +and+K i .++ +a.+ a.
What+is+the+difference+between+them?+
b. What+is+the+mathematical+relationship+between+them? - ANSWER a. β I$
