Test 1) NURS 257 Test 1 Pharmacology: Questions & Answers: Updated A+ Guide Solution

Administration of MAOI (Phenelzine) (Ans- 2 to 4 weeks to ascertain the onset of the full therapeutic effect. phentolamine or another adrenergic blocker standby in case of hypertensive crisis. Safety and S/E of MAOI (Phenelzine) (Ans- Dizziness, vertigo, headache, overactivity, hyperreflexia, tremors, mania, weakness, drowsiness, fatigue, sweating, orthostatic hypotension, constipation, diarrhea, dry mouth, edema, anorexia, potential for hypertensive crisis. Risk of suicidality. Discontinue drug if ℅ of severe h/a. Teaching r/t SSRI's (Citalopram, Fluoxetine, Sertraline) (Ans- 4 weeks is necessary for realization of the full therapeutic effect. barrier contraceptives to prevent pregnancy Citalopram, Fluoxetine, Sertraline (Ans- SSRI's (Selective serotonin reuptake inhibitors) Assessment of SSRI's (Citalopram, Fluoxetine, Sertraline) (Ans- Contraindications severely depressed or suicidal patients Action and indications of SSRI's (Citalopram, Fluoxetine, Sertraline) (Ans- blocking the reuptake of serotonin increases the levels of serotonin in the synaptic cleft Treatment of depression, OCDs, panic attacks, bulimia, premenstrual dysphoric disorder (PMDD), posttraumatic stress disorders, social phobias, and social anxiety disorders Administration of SSRI's (Citalopram, Fluoxetine, Sertraline) (Ans- Lower dose for liver/renal in elderly drug once a day in the morning S/E of SSRI's (Citalopram, Fluoxetine, Sertraline) (Ans- Not associated with many of the CNS, CV, and anticholinergic effects of other antidepressants. Headache, nervousness, insomnia, drowsiness, anxiety, tremor, dizziness, sweating, rash, nausea, vomiting, diarrhea, dry mouth, anorexia, sexual dysfunction, upper respiratory infections, weight loss, fever. Safety of SSRI's (Citalopram, Fluoxetine, Sertraline) (Ans- suicide precautions (increased SI for pediatrics) Increased bleeding risk (no NSAIDs etc.) What antidepressants are SSRIs? (Ans- citalopram, fluoxetine, sertraline What antidepressants are SNRIs? (Ans- duloxetine, venlafaxine What antidepressants are tricyclics? (Ans- amitriptyline, imipramine