BIO 351 MODULE 3 DEVELOPMENT OF THE
NERVOUS SYSTEM
Module 3 Quiz 1 - ANSWER 1. The neural tube forms from the folding of the
neural plate. Which region of the neural plate
fuses together to form the dorsal
neural tube?
C
2. The neural tube forms from the folding of the neural plate. Which region of
the neural tube is the first to close?
B
3. In the mouse embryo, this tissue provides important cues that specify the
anterior-posterior orientation of the primitive streak. Name this tissue.
anterior visceral endoderm
4. The brain is derived from which of the following?
ectoderm
Quiz 3.2 - ANSWER 1.The brain derives from which of the following types of
embryonic cells?
Ectoderm
2.Which of the following defects is a severe open neural tube defect caused by
failure of rostral neural tube closure?
anencephaly
3.The neural tube forms from the folding of the neural plate. Which region of
the neural plate fuses together to form the dorsal neural tube?
C
4.Which of the following is an occult, and not an open, neural tube defect?
Spina bifida occulta
, Quiz 3.3 - ANSWER 1.The neural tube is regionalized by developmental gene
regulation. Which of the following correctly matches the gene and specified
region?
Shh - ventralizing the neural tube
2.Which of the following regulates the segmentation of the hindbrain
rhombomeres? Hox gene expression
3.Which of the following are the initial brain vesicles, in a rostral-caudal order?
Forebrain-midbrain-hindbrain
4.Which of these central nervous system structures are correctly listed in a
rostral to caudal order?
Cerebrum, Medulla, Spinal Cord
Quiz 3.4 - ANSWER 1. You create an ephrinB2 knockout mouse. Where
would you expect to see neural crest cells migrate?
In all regions of somites
2.Melanoblastsn are derived from trunk neural crest cells that migrate from the
__________________and through the skin towards the ______________ side
of the embryo. This explains the type of phenotype observed in this mouse
mutant shown below.
Dorsal neural tube. ventral
3.The pattern of migration of cranial neural crest is shaped by the segmental
organization present in which of the following? Rhombomeres
4.In the diagram of neural tube folding, indicate the region of tissue that will
eventually form the neural crest.
C
Quiz 3.5 - ANSWER 1.Which of the following events typically occurs the
earliest during mammalian nervous system development?
Birth of motor neurons in the ventral spinal cord
NERVOUS SYSTEM
Module 3 Quiz 1 - ANSWER 1. The neural tube forms from the folding of the
neural plate. Which region of the neural plate
fuses together to form the dorsal
neural tube?
C
2. The neural tube forms from the folding of the neural plate. Which region of
the neural tube is the first to close?
B
3. In the mouse embryo, this tissue provides important cues that specify the
anterior-posterior orientation of the primitive streak. Name this tissue.
anterior visceral endoderm
4. The brain is derived from which of the following?
ectoderm
Quiz 3.2 - ANSWER 1.The brain derives from which of the following types of
embryonic cells?
Ectoderm
2.Which of the following defects is a severe open neural tube defect caused by
failure of rostral neural tube closure?
anencephaly
3.The neural tube forms from the folding of the neural plate. Which region of
the neural plate fuses together to form the dorsal neural tube?
C
4.Which of the following is an occult, and not an open, neural tube defect?
Spina bifida occulta
, Quiz 3.3 - ANSWER 1.The neural tube is regionalized by developmental gene
regulation. Which of the following correctly matches the gene and specified
region?
Shh - ventralizing the neural tube
2.Which of the following regulates the segmentation of the hindbrain
rhombomeres? Hox gene expression
3.Which of the following are the initial brain vesicles, in a rostral-caudal order?
Forebrain-midbrain-hindbrain
4.Which of these central nervous system structures are correctly listed in a
rostral to caudal order?
Cerebrum, Medulla, Spinal Cord
Quiz 3.4 - ANSWER 1. You create an ephrinB2 knockout mouse. Where
would you expect to see neural crest cells migrate?
In all regions of somites
2.Melanoblastsn are derived from trunk neural crest cells that migrate from the
__________________and through the skin towards the ______________ side
of the embryo. This explains the type of phenotype observed in this mouse
mutant shown below.
Dorsal neural tube. ventral
3.The pattern of migration of cranial neural crest is shaped by the segmental
organization present in which of the following? Rhombomeres
4.In the diagram of neural tube folding, indicate the region of tissue that will
eventually form the neural crest.
C
Quiz 3.5 - ANSWER 1.Which of the following events typically occurs the
earliest during mammalian nervous system development?
Birth of motor neurons in the ventral spinal cord
