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BIO 351 FINAL EXAM STUDY GUIDE QUESTIONS AND CORRECT DETAILED / VERIFIED ANSWERS

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A Farmer has several ewes (female sheep) that ate skuck cabbage or California hellebore while they were pregnant. What Potnetial developmental defects will be detected in their lambs? - ANS Cyclopia and holoprosencephaly From the list above pick the minimal elements required to construct a transgene that will be expressed in their liver only. - ANS liver, specific promoter, intron, Lac-z ( Beta-glactosidase) gene, 3' UTP (untranslated region) A patient presents with a congenital abnormality in the formation of the hand as shown on the right. The rest of the limb in unaffected. The most likely gene mutation would be in which of the following - ANS Hox Group 13 Which of the following processes is most important during development for the formation of the mesoderm and endoderm. - ANS Gastrulation Somites form in a ______ sequence. The location of somite formation is dependent upon a gradient of ______, patterning cue with high levels of expression in the tailbud. - ANS Rostral to caudal, FGF8

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K
BIO 351 FINAL EXAM STUDY




C
GUIDE QUESTIONS AND
LO
CORRECT DETAILED /
YC
VERIFIED ANSWERS LATEST
UPDATE
D
U
ST

, A Farmer has several ewes (female sheep) that ate skuck cabbage or California hellebore while
they were pregnant. What Potnetial developmental defects will be detected in their lambs? -
ANS Cyclopia and holoprosencephaly

From the list above pick the minimal elements required to construct a transgene that will be
expressed in their liver only. - ANS liver, specific promoter, intron, Lac-z ( Beta-glactosidase)
gene, 3' UTP (untranslated region)

A patient presents with a congenital abnormality in the formation of the hand as shown on the
right. The rest of the limb in unaffected. The most likely gene mutation would be in which of the




K
following - ANS Hox Group 13

Which of the following processes is most important during development for the formation of the




C
mesoderm and endoderm. - ANS Gastrulation

Somites form in a ______ sequence. The location of somite formation is dependent upon a




LO
gradient of ______, patterning cue with high levels of expression in the tailbud. - ANS Rostral
to caudal, FGF8

In the early embryo what signals must occur together in the splanchnic mesoderm for
cardiogenic mesoderm to be specified? - ANS DKK, Crescent, Cerberus, FGF8, and BMP
YC
Embryonically germ cells are exposed to retinoic acid which induces the onset of meiosis in
female germ cells only. Which of the following block meiosis in male germ cells? - ANS
cyp26b1, stra8, and nanos2

A 25-year old man visits his doctor to determine the cause of his infertility. Semen analysis
D

revealed round nonmotile sperm with a DNA content at n. The patient's infertility in most likely
due to a functional defect in which of the following? - ANS Spermiognesis
U


Genetic deletion of _____ would be the most likely candidate for selectively disrupting the ability
to sense pain. - ANS TrkA
ST




Which embryological tissue gives rise to the lens? - ANS Cranial placode

Which of the following elements provides the genomic signal that instructs the initiation of gene
transcription. - ANS promoter

The normal morphogen gradient in a limb bud is shown the panel on the right shows levels of
morphogen after a bead soaked with SHH is placed in transplanted into the zone of polarizing
activity of a limb bud. Which of the following best describes the expected pattern of digits? -
ANS on exam 13 diagram

Which of the following is the end result of spermatogenesis? - ANS haploid round spermatid

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