Biochemistry
Overview Of Hemostatic Systems
Compiled By Simon Mwangi
Edition: 2024/25
, Science | Biochemistry I of VIII pages
1. hemostatic system
ancestral system designed to keep an individual from bleeding
2. what other systems within the body does the hemostatic system include? (7)
vascular system
coagulation system
fibrinolytic system
platelets
kinin system
serine protease inhibitors
complement system
3. 3 main stages of the hemostatic system
vasoconstriction of blood vessels
formation of a platelet plug
blood clotting which reinforces the platelet plug with a fibrin mesh
4. what does a balance between procoagulant and anticoagulant forces maintain?
blood in a fluid state and flowing through the vasculature to deliver oxygen to tissues systemically and remove
5. where does the term hemostasis come from
greek words heme=blood + states halt= halt from blood
6. why do you pinch a cut?
to prevent blood flow
7. decreased blood pressure can lead to which 2 mechanisms?
endocrine mechanism
neural mechanism
8. endocrine mechanism
ASH, angiotensin 2, aldosterone, EPO releasedincrease in blood volume homeostasis restored
9. neural mechanism
baroreceptors, chemoreceptors stimulated cardiovascular centers stimulated general sympathetic activation,
increase cardiac output peripheral vasoconstriction, increase blood pressure, decrease venous reserve
homeostasis restored
10. vasoconstriction
contraction of smooth muscle cells to vessel walls to restrict the loss/flow of blood at site of injury
11. what is the mechanism of vasoconstriction?
sympathetic nerves trigger reflexive contraction of vascular smooth muscle
12. what are the other regulatory substances which also affect vascular tone? (3)
serotoninendothelia-1histamine
Biochemistry 2024/25 Edition
Overview Of Hemostatic Systems
Compiled By Simon Mwangi
Edition: 2024/25
, Science | Biochemistry I of VIII pages
1. hemostatic system
ancestral system designed to keep an individual from bleeding
2. what other systems within the body does the hemostatic system include? (7)
vascular system
coagulation system
fibrinolytic system
platelets
kinin system
serine protease inhibitors
complement system
3. 3 main stages of the hemostatic system
vasoconstriction of blood vessels
formation of a platelet plug
blood clotting which reinforces the platelet plug with a fibrin mesh
4. what does a balance between procoagulant and anticoagulant forces maintain?
blood in a fluid state and flowing through the vasculature to deliver oxygen to tissues systemically and remove
5. where does the term hemostasis come from
greek words heme=blood + states halt= halt from blood
6. why do you pinch a cut?
to prevent blood flow
7. decreased blood pressure can lead to which 2 mechanisms?
endocrine mechanism
neural mechanism
8. endocrine mechanism
ASH, angiotensin 2, aldosterone, EPO releasedincrease in blood volume homeostasis restored
9. neural mechanism
baroreceptors, chemoreceptors stimulated cardiovascular centers stimulated general sympathetic activation,
increase cardiac output peripheral vasoconstriction, increase blood pressure, decrease venous reserve
homeostasis restored
10. vasoconstriction
contraction of smooth muscle cells to vessel walls to restrict the loss/flow of blood at site of injury
11. what is the mechanism of vasoconstriction?
sympathetic nerves trigger reflexive contraction of vascular smooth muscle
12. what are the other regulatory substances which also affect vascular tone? (3)
serotoninendothelia-1histamine
Biochemistry 2024/25 Edition
