Biochemistry
Passive, Facilitated, And Active Transport
Compiled By Simon Mwangi
Edition: 2024/25
, Science | Biochemistry I of IV pages
1. the hydrophobic interior of a lipid bilayer prevents the passage of most
polar molecules
2. cells have specialized to transfer specific water soluble molecules and ions across their membranes
transmembrane proteins
3. the major classes of membrane transport proteins are known as (2)
transporters (carriers or permeases) and channels
4. passive/faciliated diffusion
channels and transporters which allow solute to cross the cell membrane down a concentration gradient
5. in the case of a single uncharged molecule, the on each side of the membrane drives passive transport and
concentration
high to low
6. in the case of a solute that carries a net charge, both its and influence transport
concentration gradient
electrical potential difference
7. the concentration gradient and the electrical gradient combine to form the
net driving force/electrochemical gradient
8. smaller, hydrophobic molecules diffuse across a bilayer
faster
9. types of molecules which can pass through channels depends on (2)
diameter
amino acids that make up the lining of the channel and how they interact with the molecule
10. energy used by carrier proteins (3)
ATP hydrolysis mechanical energy from movement of H+ through the channellight
11. electrochemical gradient
when one side of the membrane is more positively charged than the other
12. carrier proteins mediate passive transport via
conformational changes
13. for simple diffusion, the rate of transport is proportional to the
concentration of molecule being transported
14. for transporter mediated, the rate of transport reaches a maximum when transport protein is
saturated
15. the 1/2 Vmax and Km for carrier mediated is similar to those values for
enzyme:substrate kinetics
Biochemistry 2024/25 Edition
Passive, Facilitated, And Active Transport
Compiled By Simon Mwangi
Edition: 2024/25
, Science | Biochemistry I of IV pages
1. the hydrophobic interior of a lipid bilayer prevents the passage of most
polar molecules
2. cells have specialized to transfer specific water soluble molecules and ions across their membranes
transmembrane proteins
3. the major classes of membrane transport proteins are known as (2)
transporters (carriers or permeases) and channels
4. passive/faciliated diffusion
channels and transporters which allow solute to cross the cell membrane down a concentration gradient
5. in the case of a single uncharged molecule, the on each side of the membrane drives passive transport and
concentration
high to low
6. in the case of a solute that carries a net charge, both its and influence transport
concentration gradient
electrical potential difference
7. the concentration gradient and the electrical gradient combine to form the
net driving force/electrochemical gradient
8. smaller, hydrophobic molecules diffuse across a bilayer
faster
9. types of molecules which can pass through channels depends on (2)
diameter
amino acids that make up the lining of the channel and how they interact with the molecule
10. energy used by carrier proteins (3)
ATP hydrolysis mechanical energy from movement of H+ through the channellight
11. electrochemical gradient
when one side of the membrane is more positively charged than the other
12. carrier proteins mediate passive transport via
conformational changes
13. for simple diffusion, the rate of transport is proportional to the
concentration of molecule being transported
14. for transporter mediated, the rate of transport reaches a maximum when transport protein is
saturated
15. the 1/2 Vmax and Km for carrier mediated is similar to those values for
enzyme:substrate kinetics
Biochemistry 2024/25 Edition
