RECALL TEST QUESTIONS
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AND CORRECT DETAILED /
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VERIFIED ANSWERS LATEST
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Penicillinase-resistant penicillins - ANS Oxacillin, nafcillin, dicloxacillin
broad spectrum penicillins - ANS - ampicillin and amoxicillin
- good oral absorption (amoxicillin = excellent)
- broad spectrum (improved against gram negative organisms - e.coli, salmonella, shigella, H.
Influenza, H pylori, proteus)
How do penicillins and cephalosporins work? - ANS By weakening the cell wall and promoting
lysis and death
, Bactericidal drugs are - ANS Directly lethal to bacteria at achievable concentrations
Why are narrow spectrum drugs preferred over broad spectrum antibiotics? - ANS Broad
spectrum antibiotics do the most to facilitate emergence of resistance
How does bacterial resistance develop with penicillins? - ANS -production of penicillin binding
proteins that have low affinity for penicillins
-inability of penicillins to reach their target
-inactivation of penicillins by bacterial enzymes
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Mary is a 20 year old female. You have diagnosed him with strep throat. She has had an
anaphylactic reaction to penicillin. Which of the following antibiotics is appropriate for Mary? -
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ANS Azithromycin
What are penicillinases? - ANS Beta-lactamases that act selectively on penicillins
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The following are Penicillinase-resistant penicillins - ANS Oxacillin, Dicloxacillin, Nafcillin
The following are broad spectrum penicillins (aminopenicillins) - ANS Amoxicillin and ampicillin
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The following are extended-spectrum penicillins (antipseudomonal) - ANS Ticarcillin and
Piperacillin
The following are beta-lactamase inhibitors - ANS Sulbactam, tazobactam and clavulanic acid
Which cephalosporins are rarely used for active infections? - ANS Second generation
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Jack is taking Coumadin for his atrial fibrillation. Which of the following cephalosporins should
not be prescribed for jack? - ANS Ceftriaxone and cefotetan
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Third generation cephalosporins are good to treat - ANS Meningitis
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Fourth Generation Cephalosporins are good to treat? - ANS Pneumonia
Vancomycin works by - ANS Inhibiting Cell wall synthesis
Fluoroquinolones work by - ANS Disrupting DNA replication and cell revision
Jackson has community acquired pneumonia mycoplasma pneumonia is suspected. Which of
the following is the best choice for treatment? - ANS Doxycycline
Michael is taking simvastatin for his cholesterol. Which antibiotic should not be prescribed? -
ANS Erythromycin