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NURS 5334 - ANTIMICROBIAL RECALL TEST QUESTIONS AND CORRECT DETAILED / VERIFIED ANSWERS LATEST UPDATE

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Penicillinase-resistant penicillins - ANS Oxacillin, nafcillin, dicloxacillin broad spectrum penicillins - ANS - ampicillin and amoxicillin - good oral absorption (amoxicillin = excellent) - broad spectrum (improved against gram negative organisms - , salmonella, shigella, H. Influenza, H pylori, proteus) How do penicillins and cephalosporins work? - ANS By weakening the cell wall and promoting lysis and death Bactericidal drugs are - ANS Directly lethal to bacteria at achievable concentrations Why are narrow spectrum drugs preferred over broad spectrum antibiotics? - ANS Broad spectrum antibiotics do the most to facilitate emergence of resistance How does bacterial resistance develop with penicillins? - ANS -production of penicillin binding proteins that have low affinity for penicillins -inability of penicillins to reach their target -inactivation of penicillins by bacterial enzymes Mary is a 20 year old female. You have diagnosed him with strep throat. She has had an anaphylactic reaction to penicillin. Which of the following antibiotics is appropriate for Mary? - ANS Azithromycin What are penicillinases? - ANS Beta-lactamases that act selectively on penicillins The following are Penicillinase-resistant penicillins - ANS Oxacillin, Dicloxacillin, Nafcillin The following are broad spectrum penicillins (aminopenicillins) - ANS Amoxicillin and ampicillin The following are extended-spectrum penicillins (antipseudomonal) - ANS Ticarcillin and Piperacillin The following are beta-lactamase inhibitors - ANS Sulbactam, tazobactam and clavulanic acid Which cephalosporins are rarely used for activ

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NURS 5334 - ANTIMICROBIAL
RECALL TEST QUESTIONS




K
C
AND CORRECT DETAILED /

LO
VERIFIED ANSWERS LATEST
UPDATE
YC
D
U
ST




Penicillinase-resistant penicillins - ANS Oxacillin, nafcillin, dicloxacillin

broad spectrum penicillins - ANS - ampicillin and amoxicillin
- good oral absorption (amoxicillin = excellent)
- broad spectrum (improved against gram negative organisms - e.coli, salmonella, shigella, H.
Influenza, H pylori, proteus)

How do penicillins and cephalosporins work? - ANS By weakening the cell wall and promoting
lysis and death

, Bactericidal drugs are - ANS Directly lethal to bacteria at achievable concentrations

Why are narrow spectrum drugs preferred over broad spectrum antibiotics? - ANS Broad
spectrum antibiotics do the most to facilitate emergence of resistance

How does bacterial resistance develop with penicillins? - ANS -production of penicillin binding
proteins that have low affinity for penicillins
-inability of penicillins to reach their target
-inactivation of penicillins by bacterial enzymes




K
Mary is a 20 year old female. You have diagnosed him with strep throat. She has had an
anaphylactic reaction to penicillin. Which of the following antibiotics is appropriate for Mary? -




C
ANS Azithromycin

What are penicillinases? - ANS Beta-lactamases that act selectively on penicillins




LO
The following are Penicillinase-resistant penicillins - ANS Oxacillin, Dicloxacillin, Nafcillin

The following are broad spectrum penicillins (aminopenicillins) - ANS Amoxicillin and ampicillin
YC
The following are extended-spectrum penicillins (antipseudomonal) - ANS Ticarcillin and
Piperacillin

The following are beta-lactamase inhibitors - ANS Sulbactam, tazobactam and clavulanic acid

Which cephalosporins are rarely used for active infections? - ANS Second generation
D

Jack is taking Coumadin for his atrial fibrillation. Which of the following cephalosporins should
not be prescribed for jack? - ANS Ceftriaxone and cefotetan
U


Third generation cephalosporins are good to treat - ANS Meningitis
ST




Fourth Generation Cephalosporins are good to treat? - ANS Pneumonia

Vancomycin works by - ANS Inhibiting Cell wall synthesis

Fluoroquinolones work by - ANS Disrupting DNA replication and cell revision

Jackson has community acquired pneumonia mycoplasma pneumonia is suspected. Which of
the following is the best choice for treatment? - ANS Doxycycline

Michael is taking simvastatin for his cholesterol. Which antibiotic should not be prescribed? -
ANS Erythromycin

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