RECALL TEST QUESTIONS
K
C
AND CORRECT DETAILED /
LO
VERIFIED ANSWERS LATEST
UPDATE
YC
D
U
ST
How do penicillins and cephalosporins work? - ANS weaken cell wall and promote lysis and
cell death
Bactericidal drugs are: - ANS are directly lethal to bacteria at achievable concentrations
Why are narrow spectrum antibiotics preferred over broad spectrum antibiotics? - ANS Broad
spectrum antibiotics do the most to facilitate emergence of resistance
, How does bacterial resistance develop with penicillins? - ANS production of penicillin binding
proteins that have *low affinity* for penicillins
inability of penicillins to reach their target
inactivation of penicillins by bacterial enzymes
Strep throat treatment with PCN allergy? - ANS Azithromycin
K
What are penicillinases? - ANS beta-lactamases that act selectively on penicillins
List penicillinase-resistant penicillin: - ANS Nafcillin
C
Dicloxacillin
Oxacillin
LO
Broad spectrum penicillin? - ANS Amoxicillin
Ampicillin
Extended spectrum penicillin? - ANS Piperacillin
YC
Beta-lactamase inhibitors? - ANS Clavulanic acid
Sulbactam
Tazobactam
Cephalosporins you should not give to alcoholics? - ANS Cefazolin
cefmetazole
D
cefoperazone
cefotetan
U
What is first generation cephalosporins used for? - ANS Surgical prophylaxis
Cefadroxil
Cephalexin
ST
What cephalosporin should people on coumadin avoid? - ANS cefotetan
ceftriaxone
cefmetazole
cefoperazone
*decrease prothrombin, interferes with vit. k*
3rd Generation cephalosporins treat? - ANS meningitis
*can penetrate spinal fluid*
4th Generation cephalosporins treat? - ANS upper resp tract infections: