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NURS 5334 - ANTIMICROBIAL RECALL TEST QUESTIONS AND CORRECT DETAILED / VERIFIED ANSWERS LATEST UPDATE

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How do penicillins and cephalosporins work? - ANS weaken cell wall and promote lysis and cell death Bactericidal drugs are: - ANS are directly lethal to bacteria at achievable concentrations Why are narrow spectrum antibiotics preferred over broad spectrum antibiotics? - ANS Broad spectrum antibiotics do the most to facilitate emergence of resistance How does bacterial resistance develop with penicillins? - ANS production of penicillin binding proteins that have *low affinity* for penicillins inability of penicillins to reach their target inactivation of penicillins by bacterial enzymes Strep throat treatment with PCN allergy? - ANS Azithromycin What are penicillinases? - ANS beta-lactamases that act selectively on penicillins List penicillinase-resistant penicillin: - ANS Nafcillin Dicloxacillin Oxacillin Broad spectrum penicillin? - ANS Amoxicillin Ampicillin Extended spectrum penicillin? - ANS Piperacillin Beta-lactamase inhibitors? - ANS Clavulanic acid Sulbactam Tazobactam Cephalosporins you should not give to alcoholics? - ANS Cefazolin cefmetazole cefoperazone cefotetan What is first generation cephalosporins used for? - ANS Surgical prophylaxis Cefadroxil Cephalexin What cephalosporin should people on coumadin avoid? - ANS cefotetan ceftriaxone cefmetazole cefoperazone *decrease prothrombin, interferes with vit. k* 3rd Generation cephalosporins treat? - ANS meningitis *can penetrate spinal fluid* 4th Generation cephalosporins treat? - ANS upper resp tract infections: pneumonia Vancomycin works by? - ANS stops cell wall synthesis How to treat community acquired pneumonia caused by Myc

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NURS 5334 - ANTIMICROBIAL
RECALL TEST QUESTIONS




K
C
AND CORRECT DETAILED /

LO
VERIFIED ANSWERS LATEST
UPDATE
YC
D
U
ST




How do penicillins and cephalosporins work? - ANS weaken cell wall and promote lysis and
cell death

Bactericidal drugs are: - ANS are directly lethal to bacteria at achievable concentrations

Why are narrow spectrum antibiotics preferred over broad spectrum antibiotics? - ANS Broad
spectrum antibiotics do the most to facilitate emergence of resistance

, How does bacterial resistance develop with penicillins? - ANS production of penicillin binding
proteins that have *low affinity* for penicillins

inability of penicillins to reach their target

inactivation of penicillins by bacterial enzymes

Strep throat treatment with PCN allergy? - ANS Azithromycin




K
What are penicillinases? - ANS beta-lactamases that act selectively on penicillins

List penicillinase-resistant penicillin: - ANS Nafcillin




C
Dicloxacillin
Oxacillin




LO
Broad spectrum penicillin? - ANS Amoxicillin
Ampicillin

Extended spectrum penicillin? - ANS Piperacillin
YC
Beta-lactamase inhibitors? - ANS Clavulanic acid
Sulbactam
Tazobactam

Cephalosporins you should not give to alcoholics? - ANS Cefazolin
cefmetazole
D

cefoperazone
cefotetan
U


What is first generation cephalosporins used for? - ANS Surgical prophylaxis
Cefadroxil
Cephalexin
ST




What cephalosporin should people on coumadin avoid? - ANS cefotetan
ceftriaxone
cefmetazole
cefoperazone
*decrease prothrombin, interferes with vit. k*

3rd Generation cephalosporins treat? - ANS meningitis
*can penetrate spinal fluid*

4th Generation cephalosporins treat? - ANS upper resp tract infections:

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