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BIOS 242 Week 5 With Correct Answers 100% Verified

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BIOS 242 Week 5 With Correct Answers 100% Verified



Species resistance - ANSWER due to physiological processes of humans that are
incompatible with those of the pathogen



Innate immunity - ANSWER first line of defense (born with) and works nonspecifically
and quickly



immunity - ANSWER I recognize me and what belongs to me and I can recognize things
that do not belong



first line of defense - structures, chemicals and processes which prevent entry into the
body, which in most cases are physical barriers



skin - what major organ is involved with innate immunity?



epidermis and dermis - two layers of skin



epidermis - multiple layers of tightly packed cells, few pathogens are able to penetrate
these layers and also dead skin cells are constantly sloughed off removing
microorganisms



dermis - ANSWER collagen fibers help skin resist abrasions that could introduce
microorganisms



sweat - ANSWER high salt concentration changes pH (messes with a narrow range that
microbes need thus killing them)



antimicrobial peptides - ANSWER act against microorganisms

,defensins - ANSWER antimicrobial peptides that inhibit microbial growth



lysozyme - ANSWER destroy cell wall of bacteria (lyses cell)



sebum - ANSWER secreted by sebaceous (oil) glands, helps keep skin pliable and less
likely to break or tear, also helps lower skin pH to a level inhibitory to many bacteria



mucous membrane - ANSWER line all body cavities that open to the outside of the body
(nose, esophagus, GI tract, etc.)



epithelium a thin outer covering of the mucous membranes, living cells, tightly packed
to prevent entry of many pathogens, continual shedding of cells carries away
microorganisms, contain dendritic cells



dendritic cells below epithelium and help phagocytize pathogens



goblet and ciliated columnar cells help remove invaders



mucous membranes produce chemicals that defend against pathogens



mucus - ANSWER defense because it contains cilia and has peristalsis to expel stuff also
sticky so it traps stuff



lacrimal apparatus - ANSWER produces and drains tears, blinking spreads tears and
washes surface of the eye and contains lysozyme



lysozyme - ANSWER enzyme in tears that destroys bacteria

, Immune privileged sites - ANSWER they are able to tolerate the introduction of antigens
without eliciting an inflammatory immune response.



micro-metrical antagonism ANSWER microbiome competes w/ potential pathogens, or
normal flora keeps it in check because their survival lessens survival of others



microbiome ANSWER normally harmless residents of body comprise the human flora all
microbes in a particular environment



consumption of nutrients, create an unfavorable environment, prevent attachment to
host cells, stimulates second line of defense, and provides vitamins to host - ANSWER
how do members of the microbiome make it hard for pathogens to compete?



antimicrobial peptides - ANSWER present in skin, mucous membranes, neutrophils and
act against a variety of microbes (not specific) by working in conjunction with other
things



peptides - ANSWER small proteins



saliva - ANSWER washes microbes from teeth, gums, tongue, and palate (contain
lysozyme)



stomach acid - ANSWER digests and or inhibits microorganisms (low pH)

gastroferritin - ANSWER sequesters iron being absorbed, making it unavailable for
microbial use



bile - ANSWER inhibitory to most microorganisms



peristalsis - ANSWER moves GI contents through GI tract, constantly eliminating
potential pathogens

defecation and vomitting - ANSWER two ways that the body can eliminate

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