c c c c c c c c c c c
Michelle J. Willihnganz, Samuel L. Gurevitz, Bruce Clayton Complete
c c c c c c c c
,Chapter 01: Drug Definitions, Standards, and Information Sources Willihnganz:
c c c c c c c c c
Clayton’s Basic Pharmacology for Nurses, 19th Edition
c c c c c c
MULTIPLEcCHOICE
1. WhichcnamecidentifiescacdrugclistedcbycthecUScFoodcandc
DrugcAdministrationc(FDA)?
a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS:c C
Thecofficialcnameciscthec namecundercwhichcacdrugcisclistedcbyc
thecFDA.cThecbrandcname,corctrademark,ciscthecnamecgivenctoc
acdrugcbycitscmanufacturer.cThecnonproprietary,corcgeneric,cna
meciscprovidedcbycthecUnitedcStatescAdoptedcNamescCouncil.
DIF: CognitivecLevel:cKnowledge REF:c p.c9
OBJ:c1NAT:cNCLEXcClientcNeedscCategory:cSafe,cEffectivecCarec
EnvironmentcTOP:c NursingcProcesscStep:cAssessment
CON:c
PatientcEducation
2. Whichcsourceccontainscinformationcspecificctocnutritionalcsupplements?
a. USPcDictionarycofcUSANc &cInternationalcDrugcNames
b. NaturalcMedicinescComprehensivecDatabase
c. UnitedcStatescPharmacopoeia/NationalcFormularyc(USPcNF)
d. DrugcInteractioncFacts
ANS:c C
UnitedcStatescPharmacopoeia/NationalcFormularyccontainscinformationcspecificctocnutritionalcs
upplements.cUSPcDictionarycofcUSANc&cInternationalcDrugcNamesciscaccompilationcofcdrugcna
mes,cpronunciationcguide,candcpossiblecfuturecFDAcapprovedcdrugs;citcdoescnotcincludecnutritio
nalcsupplements.cNaturalcMedicinescComprehensivecDatabaseccontains
evidence-
basedcinformationconcherbalcmedicinescandcherbalccombinationcproducts;citcdoescnotcincludecinfo
rmationcspecificctocnutritionalcsupplements.cDrugcInteractioncFactsccontainsccomprehensivecin
formationconcdrugcinteractioncfacts;citcdoescnotcincludecnutritionalcsupplements.
DIF: CognitivecLevel:cKnowledge REF:c p.c4
OBJ:c3cNAT:c NCLEXcClientcNeedscCategory:cPhysiologicalcIntegr
ity
TOP:c NursingcProcesscStep:cAssessment CON:c Nutritionc|cPatientcEducation
3. Whichcdrugcreferenceccontainscdrugcmonographscthatcdescribecallcdrugscincactherapeuticcclass?
a. DrugcFactscandcComparisons
,TestcBankcForcClayton’scBasiccPharmacologycforcNursesc19thcEdition 3
b. DrugcInteractioncFacts
c. HandbookconcInjectablecDrugs
d. Martindale—ThecCompletecDrugcReference
ANS:c A
DrugcFactscandcComparisonsccontainscdrugcmonographscthatcdescribecallcdrugscincacthe
rapeuticcclass.cMonographscarecformattedcasctablesctocallowccomparisoncofcsimilarcprodu
cts,cbrandcnames,cmanufacturers,ccostcindices,candcavailablecdosagecformscOnlinecversi
onciscavailable.
DIF: CognitivecLevel:cKnowledge REF:c p.c4cTablec1.2
OBJ:ccc 3 NAT:c NCLEXcClientcNeedscCategory:cPhysiologicalcIntegrity
TOP:c NursingcProcesscStep:cAssessment CON:c Safetyc|cPatientcEducationc|cClinicalcJudgment
4. Whichcdrugcreferenceccontainscmonographscaboutc virtuallyceverycsingle-
entitycdrugcavailablecincthecUnitedcStatescandcdescribesctherapeuticcusescofcdrugs,cincludingcapp
rovedcandcunapprovedcuses?
a. Martindale:cThecCompletecDrugcReference
b. AHFScDrugcInformation
c. DrugcReference
d. DrugcFactscandcComparisons
ANS:c B
AHFScDrugcInformationccontainscmonographscaboutcvirtuallyceverycsingle-
entitycdrugcavailablecincthecUnitedcStatescandcdescribesctherapeuticcusescofcdrugs,cincludingcappr
ovedcandcunapprovedcuses.
DIF: CognitivecLevel:cKnowledge REF:c p.c4cTablec1.2
OBJ:ccc 3 NAT:c NCLEXcClientcNeedscCategory:cPhysiologicalcIntegrity
TOP:c NursingcProcesscStep:cPlanning CON:c Safetyc|cPatientcEducationc|cClinicalcJudgment
5. Whichconlinecdrugcreferencecmakescavailablectochealthcarecproviderscandcthecpubliccacstand
ard,ccomprehensive,cup-to-dateclookcupcandcdownloadablecresourcecaboutcmedicines?
a. AmericancDrugcIndex
b. AmericancHospitalcFormulary
c. DailyMed
d. DrugcReference
ANS:c C
DailyMedcmakescavailablectochealthcarecproviderscandcthecpubliccacstandard,ccomprehensive,cu
p-to-
dateclookcupcandcdownloadablecresourcecaboutcmedicines.cThecAmericancDrugcIndexciscnotcappr
opriatecforcpatientcuse.cThecAmericancHospitalcFormularyciscnotcappropriatecforcpatientcuse.cT
hecdrugcreferencec iscnotcappropriatecforcpatientcuse.
DIF: CognitivecLevel:cKnowledge REF:c p.c3c|cp.c4
OBJ:c3cNAT:c NCLEXcClientcNeedscCategory:cPhysiologicalcIntegr
ity
TOP:c NursingcProcesscStep:cImplementation
CON:c Safetyc|cPatientcEducationc|cClinicalcJudgment
6. WhichclegislationcauthorizescthecFDActocdeterminecthecsafetycofcacdrugcbeforecitscmarketing?
a. FederalcFood,cDrug,candcCosmeticcActc(1938)
b. DurhamcHumphreycAmendmentc(1952)
, TestcBankcForcClayton’scBasiccPharmacologycforcNursesc19thcEdition 4
c. ControlledcSubstancescActc(1970)
d. KefauvercHarriscDrugcAmendmentc(1962)
ANS:c A
ThecFederalcFood,cDrug,candcCosmeticcActcofc1938cauthorizedcthecFDActocdeterminecthecsafetyc
ofcallcdrugscbeforecmarketing.cLatercamendmentscandcactschelpedctightencFDAccontrolcandcensu
recdrugcsafety.cThecDurhamcHumphreycAmendmentcdefinesctheckindscofcdrugscthatccannotcbecus
edcsafelycwithoutcmedicalcsupervisioncandcrestrictsctheircsalectocprescriptioncbycaclicensedcpractit
ioner.cThecControlledcSubstancescActcaddressesconlyccontrolledcsubstancescandctheirccategorizati
on.cThecKefauvercHarriscDrugcAmendmentcensurescdrugcefficacycandcgreatercdrugcsafety.cDrugc
manufacturerscarecrequiredctocprovectocthecFDActheceffectivenesscofctheircproductscbeforecmarke
tingcthem.
DIF: CognitivecLevel:cKnowledge REF:cp.c5cTablecl.3
OBJ:c 5
NAT:cNCLEXcClientcNeedscCategory:cPhysiologicalcIntegrityc
TOP:c NursingcProcesscStep:cAssessment
CON:c Safetyc|cPatientcEducationc|cEvidencec|cHealthcCarecLaw
7. Whichcclassificationcdoescmeperidinec(Demerol)cfallcunder?
a. I
b. II
c. III
d. IV
ANS:c B
Meperidinec(Demerol)ciscacSchedulecIIcdrug;citchascachighcpotentialcforcabusecandcmaycleadctocse
verecpsychologicalcandcphysicalcdependence.cSchedulecIcdrugschavechighcpotentialcforcabusecandc
nocrecognizedcmedicalcuse.cSchedulecIIIcdrugschavecsomecpotentialcforcabuse.cUsecmaycleadctocl
owctocmoderatecphysicalcdependencecorchighcpsychologicalcdependence.cSchedulecIVcdrugschav
eclowcpotentialcforcabuse.cUsecmaycleadctoclimitedcphysicalcorcpsychologicalcdependence.
DIF: CognitivecLevel:cKnowledge REF:c p.c10
OBJ:c2cNAT:c NCLEXcClientcNeedscCategory:cSafe,cEffectivecCarec
Environment
TOP:c NursingcProcesscStep:cAssessment CON:c PatientcEducationc|cAddictionc|cPain
8. WhichcactioncwouldcthecFDActakectocexpeditecdrugcdevelopmentcandcapprovalcforcancoutbreakcofc
smallpox?
a. Listcsmallpoxcascachealthcorphancdisease.
b. Omitcthecpreclinicalcresearchcphase.
c. Extendcthecclinicalcresearchcphase.
d. Fastctrackcthecinvestigationalcdrug.
ANS:c D
OncecthecInvestigationalcNewcDrugcApplicationchascbeencapproved,cthecdrugccancreceivechighes
tcprioritycwithincthecagency,cwhichcisccalledcfastctracking.cAcsmallpoxcoutbreakcwouldcbecomecac
prioritycconcerncincthecworld.cOrphancdiseasescarecnotcresearchedcincacprioritycmanner.cPreclinic
alcresearchciscnotcomitted.cExtendingcanycphasecofcthecresearchcwouldcmeancaclongerctimectocdeve
lopcacvaccine.cThecFDAcmustcensurecthatcallcphasescofcthecpreclinicalcandcclinicalcresearchcphasec
havecbeenccompletedcincacsafecmanner.
DIF: CognitivecLevel:cKnowledge REF:cccp.c7 OBJ:c 5