Sue E. Huether, Kathryn L. McCance -
x x x x x x
Test Bank for Understanding Pathophysiology (6t
x x x x x x
h Ed)-Test Bank (complete questions & answers)
x x x x x x
Chapter 01: Cellular Biology
x x x
Huether & McCance: Understanding Pathophysiology, 6th Edition
x x x x x x
MULTIPLExCHOICE
1. Axstudentxisxobservingxaxcellxunderxthexmicroscope.xItxisxobservedxtoxhavexsupercoiledxDNAx
withxhistones.xWhichxofxthexfollowingxwouldxalsoxbexobservedxbyxthexstudent?
a. Axsinglexcircularxchromosome
b. Axnucleus
c. Free-floatingxnuclearxmaterial
d. Noxorganelles
ANS:x B
Thexcellxdescribedxisxaxeukaryoticxcell,xsoxitxhasxhistonesxandxaxsupercoiledxDNAxwithinxitsxn
ucleus;xthus,xthexnucleusxshouldxbexobserved.xAxsinglexcircularxchromosomexcalledxaxprokar
yotexcontainsxfree-floatingxnuclearxmaterialxbutxhasxnoxorganelles.
REF:x p.x2
2. Axnursexisxinstructingxthexstaffxaboutxcellularxfunctions.xWhichxcellularxfunctionxisxthexnursexde
scribingxwhenxanxisolatedxcellxabsorbsxoxygenxandxusesxitxtoxtransformxnutrientsxtoxenergy?
a. Metabolicxabsorption
b. Communication
c. Secretion
d. Respiration
ANS:x D NURSINGTB.COM
Thexcell’sxabilityxtoxabsorbxoxygenxisxreferredxtoxasxrespirationxwhilexitsxcommunicationxabilityxi
nvolvesxmaintenancexofxaxsteadyxdynamicxstate,xmetabolicxabsorptionxprovidesxnutrition,xandxse
cretionxallowsxforxthexsynthesizingxofxnewxsubstances.
REF:x p.x2
3. AxeukaryoticxcellxisxundergoingxDNAxreplication.xInxwhichxregionxofxthexcellxwouldxmostxofxt
hexgeneticxinformationxbexcontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. NucleusxCytoplasm
ANS:x C
Thexregionxofxthexcellxthatxcontainsxgeneticxmaterial,xincludingxaxlargexamountxofxribonucleicxa
cid,xmostxofxthexDNA,xandxDNA-
bindingxproteins,xisxthexnucleolus,xwhichxisxlocatedxwithinxthexcell’sxnucleus.xMitochondriaxisx
associatedxwithxcellularxrespiration,xwhilexribosomesxarexinvolvedxwithxproteinxmanufacturin
g.xCytoplasmxisxaxfluidxfillingxthatxisxaxcomponentxofxthexcell.
REF:x p.x2
NURSINGTB.COM
,Sue E. Huether, Kathryn L. McCance -
x x x x x x
Test Bank for Understanding Pathophysiology (6t
x x x x x x
h Ed)-Test Bank (complete questions & answers)
x x x x x x
4. Whichxofxthexfollowingxcanxremovexproteinsxattachedxtoxthexcell’sxbilayerxbyxdissolvingxthexl
ayerxitself?
a. Peripheralxmembranexproteins
b. Integralxmembranexproteins
c. Glycoproteins
d. Cellxadhesionxmolecules
ANS:x B
Proteinsxdirectlyxattachedxtoxthexmembranexbilayerxcanxbexremovedxbyxthexactionxofxintegralx
membranexproteinsxthatxdissolvexthexbilayer.xPeripheralxmembranexproteinsxresidexatxthexsurf
acexwhilexcellxadhesionxmoleculesxarexonxthexoutsidexofxthexmembrane.xGlycoproteinxmarksxc
ellsxandxdoesxnotxfloat.
REF:x p.x7
5. Whichxofxthexfollowingxcanxbindxtoxplasmaxmembranexreceptors?
a. Oxygen
b. Ribosomes
c. Amphipathicxlipids
d. Ligands
ANS:x D
Ligandsxarexthexonlyxspecificxmoleculesxthatxcanxbindxwithxreceptorsxonxthexcellxmembrane.
REF:x p.x9
6. Axnursexisxreviewingxaxreportxfromxaxpatientxwithxmetastaticxcancer.xWhatxalternationxinxthexe
xtracellularxmatrixxwouldxsuN
ppoR I exdG
iagnBo.
siC
sxofM
a. Decreasedxfibronectin
UrtxS
xth
xNxT Ometastaticxcancer?
b. Increasedxcollagen
c. Decreasedxelastin
d. Increasedxglycoproteins
ANS:x A
Onlyxaxreducedxamountxofxfibronectinxisxfoundxinxsomextypesxofxcancerousxcells,xallowingxt
hemxtoxtravelxorxmetastasize.
REF:x p.x10
7. Whichxformxofxcellxcommunicationxisxusedxtoxrelatextoxotherxcellsxinxdirectxphysicalxcontact?
a. Cellxjunction
b. Gapxjunction
c. Desmosome
d. Tightxjunction
ANS:x A
Cellxjunctionsxholdxcellsxtogetherxandxpermitxmoleculesxtoxpassxfromxcellxtoxcell.
Gapxjunctionsxallowxforxcellularxcommunicationxbetweenxcells.xNeitherxdesmosomesxnorxtightxj
unctionsxarexassociatedxwithxcellularxcommunication.
NURSINGTB.COM
,Sue E. Huether, Kathryn L. McCance -
x x x x x x
Test Bank for Understanding Pathophysiology (6t
x x x x x x
h Ed)-Test Bank (complete questions & answers)
x x x x x x
REF:x p.x11
NURSINGTB.COM
, Sue E. Huether, Kathryn L. McCance -
x x x x x x
Test Bank for Understanding Pathophysiology (6t
x x x x x x
h Ed)-Test Bank (complete questions & answers)
x x x x x x
8. Pancreaticxbetaxcellsxsecretexinsulin,xwhichxinhibitsxsecretionxofxglucagonxfromxneighboringxa
lphaxcells.xThisxactionxisxanxexamplexofxwhichxofxthexfollowingxsignalingxtypes?
a. Paracrine
b. Autocrine
c. Neurohormonal
d. Hormonal
ANS:x A
Paracrinexsignalingxinvolvesxthexreleasexofxlocalxchemicalxmediatorsxthatxarexquicklyxtakenxup,xd
estroyed,xorximmobilized,xasxinxthexcasexofxinsulinxandxthexinhibitionxofxthexsecretionxofxglucago
n.xNonexofxthexotherxoptionsxinvolvexsignalingxthatxisxassociatedxwithxaxlocalxchemicalxmediatorx
likexinsulin.
REF:x p.x12
9. Inxcellularxmetabolism,xeachxenzymexhasxaxhighxaffinityxforxa:
a. solute.
b. substrate.
c. receptor.
d. ribosome.
ANS:x B
Eachxenzymexhasxaxhighxaffinityxforxaxsubstrate,xaxspecificxsubstancexconvertedxtoxaxproductxofxt
hexreaction.xCellularxmetabolismxisxnotxdependentxonxanxattractionxbetweenxanxenzymexandxanyx
ofxthexremainingxoptions.
REF:xxxp.x16
NURSINGTB.COM
10. Anxathletexrunsxaxmarathon,xafterxwhichxhisxmusclesxfeelxfatiguedxandxunablextoxcontract.xThexat
hletexasksxthexnursexwhyxthisxhappened.xThexnurse’sxresponsexisxbasedxonxthexknowledgexthatxthex
problemxisxresultxofxaxdeficiencyxof:
a. GTP
b. AMP
c. ATP
d. GMP
ANS:x C
WhenxATPxisxdeficient,ximpairedxmusclexcontractionxresults.xNonexofxthexotherxoptionsxarexi
nvolvedxinxmusclexcontraction.
REF:x p.x16
11. WhichxphasexofxcatabolismxproducesxthexmostxATP?
a. Digestion
b. Glycolysis
c. Oxidation
d. Citricxacidxcycle
ANS:x D
NURSINGTB.COM
x x x x x x
Test Bank for Understanding Pathophysiology (6t
x x x x x x
h Ed)-Test Bank (complete questions & answers)
x x x x x x
Chapter 01: Cellular Biology
x x x
Huether & McCance: Understanding Pathophysiology, 6th Edition
x x x x x x
MULTIPLExCHOICE
1. Axstudentxisxobservingxaxcellxunderxthexmicroscope.xItxisxobservedxtoxhavexsupercoiledxDNAx
withxhistones.xWhichxofxthexfollowingxwouldxalsoxbexobservedxbyxthexstudent?
a. Axsinglexcircularxchromosome
b. Axnucleus
c. Free-floatingxnuclearxmaterial
d. Noxorganelles
ANS:x B
Thexcellxdescribedxisxaxeukaryoticxcell,xsoxitxhasxhistonesxandxaxsupercoiledxDNAxwithinxitsxn
ucleus;xthus,xthexnucleusxshouldxbexobserved.xAxsinglexcircularxchromosomexcalledxaxprokar
yotexcontainsxfree-floatingxnuclearxmaterialxbutxhasxnoxorganelles.
REF:x p.x2
2. Axnursexisxinstructingxthexstaffxaboutxcellularxfunctions.xWhichxcellularxfunctionxisxthexnursexde
scribingxwhenxanxisolatedxcellxabsorbsxoxygenxandxusesxitxtoxtransformxnutrientsxtoxenergy?
a. Metabolicxabsorption
b. Communication
c. Secretion
d. Respiration
ANS:x D NURSINGTB.COM
Thexcell’sxabilityxtoxabsorbxoxygenxisxreferredxtoxasxrespirationxwhilexitsxcommunicationxabilityxi
nvolvesxmaintenancexofxaxsteadyxdynamicxstate,xmetabolicxabsorptionxprovidesxnutrition,xandxse
cretionxallowsxforxthexsynthesizingxofxnewxsubstances.
REF:x p.x2
3. AxeukaryoticxcellxisxundergoingxDNAxreplication.xInxwhichxregionxofxthexcellxwouldxmostxofxt
hexgeneticxinformationxbexcontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. NucleusxCytoplasm
ANS:x C
Thexregionxofxthexcellxthatxcontainsxgeneticxmaterial,xincludingxaxlargexamountxofxribonucleicxa
cid,xmostxofxthexDNA,xandxDNA-
bindingxproteins,xisxthexnucleolus,xwhichxisxlocatedxwithinxthexcell’sxnucleus.xMitochondriaxisx
associatedxwithxcellularxrespiration,xwhilexribosomesxarexinvolvedxwithxproteinxmanufacturin
g.xCytoplasmxisxaxfluidxfillingxthatxisxaxcomponentxofxthexcell.
REF:x p.x2
NURSINGTB.COM
,Sue E. Huether, Kathryn L. McCance -
x x x x x x
Test Bank for Understanding Pathophysiology (6t
x x x x x x
h Ed)-Test Bank (complete questions & answers)
x x x x x x
4. Whichxofxthexfollowingxcanxremovexproteinsxattachedxtoxthexcell’sxbilayerxbyxdissolvingxthexl
ayerxitself?
a. Peripheralxmembranexproteins
b. Integralxmembranexproteins
c. Glycoproteins
d. Cellxadhesionxmolecules
ANS:x B
Proteinsxdirectlyxattachedxtoxthexmembranexbilayerxcanxbexremovedxbyxthexactionxofxintegralx
membranexproteinsxthatxdissolvexthexbilayer.xPeripheralxmembranexproteinsxresidexatxthexsurf
acexwhilexcellxadhesionxmoleculesxarexonxthexoutsidexofxthexmembrane.xGlycoproteinxmarksxc
ellsxandxdoesxnotxfloat.
REF:x p.x7
5. Whichxofxthexfollowingxcanxbindxtoxplasmaxmembranexreceptors?
a. Oxygen
b. Ribosomes
c. Amphipathicxlipids
d. Ligands
ANS:x D
Ligandsxarexthexonlyxspecificxmoleculesxthatxcanxbindxwithxreceptorsxonxthexcellxmembrane.
REF:x p.x9
6. Axnursexisxreviewingxaxreportxfromxaxpatientxwithxmetastaticxcancer.xWhatxalternationxinxthexe
xtracellularxmatrixxwouldxsuN
ppoR I exdG
iagnBo.
siC
sxofM
a. Decreasedxfibronectin
UrtxS
xth
xNxT Ometastaticxcancer?
b. Increasedxcollagen
c. Decreasedxelastin
d. Increasedxglycoproteins
ANS:x A
Onlyxaxreducedxamountxofxfibronectinxisxfoundxinxsomextypesxofxcancerousxcells,xallowingxt
hemxtoxtravelxorxmetastasize.
REF:x p.x10
7. Whichxformxofxcellxcommunicationxisxusedxtoxrelatextoxotherxcellsxinxdirectxphysicalxcontact?
a. Cellxjunction
b. Gapxjunction
c. Desmosome
d. Tightxjunction
ANS:x A
Cellxjunctionsxholdxcellsxtogetherxandxpermitxmoleculesxtoxpassxfromxcellxtoxcell.
Gapxjunctionsxallowxforxcellularxcommunicationxbetweenxcells.xNeitherxdesmosomesxnorxtightxj
unctionsxarexassociatedxwithxcellularxcommunication.
NURSINGTB.COM
,Sue E. Huether, Kathryn L. McCance -
x x x x x x
Test Bank for Understanding Pathophysiology (6t
x x x x x x
h Ed)-Test Bank (complete questions & answers)
x x x x x x
REF:x p.x11
NURSINGTB.COM
, Sue E. Huether, Kathryn L. McCance -
x x x x x x
Test Bank for Understanding Pathophysiology (6t
x x x x x x
h Ed)-Test Bank (complete questions & answers)
x x x x x x
8. Pancreaticxbetaxcellsxsecretexinsulin,xwhichxinhibitsxsecretionxofxglucagonxfromxneighboringxa
lphaxcells.xThisxactionxisxanxexamplexofxwhichxofxthexfollowingxsignalingxtypes?
a. Paracrine
b. Autocrine
c. Neurohormonal
d. Hormonal
ANS:x A
Paracrinexsignalingxinvolvesxthexreleasexofxlocalxchemicalxmediatorsxthatxarexquicklyxtakenxup,xd
estroyed,xorximmobilized,xasxinxthexcasexofxinsulinxandxthexinhibitionxofxthexsecretionxofxglucago
n.xNonexofxthexotherxoptionsxinvolvexsignalingxthatxisxassociatedxwithxaxlocalxchemicalxmediatorx
likexinsulin.
REF:x p.x12
9. Inxcellularxmetabolism,xeachxenzymexhasxaxhighxaffinityxforxa:
a. solute.
b. substrate.
c. receptor.
d. ribosome.
ANS:x B
Eachxenzymexhasxaxhighxaffinityxforxaxsubstrate,xaxspecificxsubstancexconvertedxtoxaxproductxofxt
hexreaction.xCellularxmetabolismxisxnotxdependentxonxanxattractionxbetweenxanxenzymexandxanyx
ofxthexremainingxoptions.
REF:xxxp.x16
NURSINGTB.COM
10. Anxathletexrunsxaxmarathon,xafterxwhichxhisxmusclesxfeelxfatiguedxandxunablextoxcontract.xThexat
hletexasksxthexnursexwhyxthisxhappened.xThexnurse’sxresponsexisxbasedxonxthexknowledgexthatxthex
problemxisxresultxofxaxdeficiencyxof:
a. GTP
b. AMP
c. ATP
d. GMP
ANS:x C
WhenxATPxisxdeficient,ximpairedxmusclexcontractionxresults.xNonexofxthexotherxoptionsxarexi
nvolvedxinxmusclexcontraction.
REF:x p.x16
11. WhichxphasexofxcatabolismxproducesxthexmostxATP?
a. Digestion
b. Glycolysis
c. Oxidation
d. Citricxacidxcycle
ANS:x D
NURSINGTB.COM