BIOCHEM C785 - WGU - Module 5 - all
Questions and Answers
What vitamin does not travel through the bloodstream in the form of a lipid micelle? - Answer-Vitamin
C
Which lipid has a 4-ring structure? - Answer-Sterol
Which of the following situations is MOST likely to increase the rate of beta oxidation? - Answer-fasting
A patient who is on a no-fat diet is at particular risk of deficiency in: - Answer-Vitamin A
During starvation, triglycerides can help supply some of the body's glucose needs. Which breakdown
product of triglycerides can be used to make glucose? - Answer-glycerol
CH3(CH2)6CH=CH(CH2)2COOH - Answer-liquid at the lowest temperature
Describe the steps involved in fatty acid synthesis - Answer-Acetyl-CoA is transported to the cytoplasm -
Biotin transfers a carboxylate group to acetyl-CoA - the malonyl group is transferred to a carrier protein -
malonyl ACP combines with acetyl-CoA, - malonyl-CoA is added repeatedly to the growing fatty acid
, What fatty acid will produce 8 Acetyl CoA molecules after it is completely metabolized via beta
oxidation? - Answer-CH3(CH2)4CH=CH(CH2)4CH=CH(CH2)8COOH
Which set of molecules are produced by the beta oxidation of fatty acids? - Answer-Acetyl CoA, NADH,
FADH2
Gastric bypass surgery results in an increase in the production of GLP-1, a peptide that promotes insulin
secretion. This is thought to be associated with the tendency for these patients' type II diabetes to
resolve after the surgery. If a gastric bypass patient has a mutation in GLP-1 that impairs its function,
what is to be expected? - Answer-The patient would have reduced insulin secretion compared to
patients with normal GLP-1, and this reduction results in increased fatty acid oxidation
Through mandatory state testing, a 2-day-old newborn is found to have a medium chain acyl-COA
dehydrogenase deficiency (MCADD). This enzyme deficiency interferes with the baby's ability to break
down medium chain fatty acids via beta oxidation. Her parents need to be given specific instructions on
what the baby can ingest. What is correct? - Answer-She will not be able to utilize adipose tissue for
ATP production as effectively as a baby without the disorder
Which of the following contributes to the development of ketoacidosis in a diabetic patient - Answer-A
reduction in citric acid cycle intermediates, which decreases the amount of oxaloacetate that acetyle-
CoA can combine with to enter the citric acid cycle
What describes a fatty acid? - Answer-C16H3202
Unsaturated fatty acids can have different arrangements of hydrogen atoms at the double bond
depending on whether the bonds are cis- or trans- configuration. A consequence of this : - Answer-fatty
acids with cis-configuration double bonds do not pack together well which lowers their melting point
What best describes fatty acid hydrogenation? - Answer-Hydrogenation converts some unsaturated
fatty acids into saturated fatty acids
Questions and Answers
What vitamin does not travel through the bloodstream in the form of a lipid micelle? - Answer-Vitamin
C
Which lipid has a 4-ring structure? - Answer-Sterol
Which of the following situations is MOST likely to increase the rate of beta oxidation? - Answer-fasting
A patient who is on a no-fat diet is at particular risk of deficiency in: - Answer-Vitamin A
During starvation, triglycerides can help supply some of the body's glucose needs. Which breakdown
product of triglycerides can be used to make glucose? - Answer-glycerol
CH3(CH2)6CH=CH(CH2)2COOH - Answer-liquid at the lowest temperature
Describe the steps involved in fatty acid synthesis - Answer-Acetyl-CoA is transported to the cytoplasm -
Biotin transfers a carboxylate group to acetyl-CoA - the malonyl group is transferred to a carrier protein -
malonyl ACP combines with acetyl-CoA, - malonyl-CoA is added repeatedly to the growing fatty acid
, What fatty acid will produce 8 Acetyl CoA molecules after it is completely metabolized via beta
oxidation? - Answer-CH3(CH2)4CH=CH(CH2)4CH=CH(CH2)8COOH
Which set of molecules are produced by the beta oxidation of fatty acids? - Answer-Acetyl CoA, NADH,
FADH2
Gastric bypass surgery results in an increase in the production of GLP-1, a peptide that promotes insulin
secretion. This is thought to be associated with the tendency for these patients' type II diabetes to
resolve after the surgery. If a gastric bypass patient has a mutation in GLP-1 that impairs its function,
what is to be expected? - Answer-The patient would have reduced insulin secretion compared to
patients with normal GLP-1, and this reduction results in increased fatty acid oxidation
Through mandatory state testing, a 2-day-old newborn is found to have a medium chain acyl-COA
dehydrogenase deficiency (MCADD). This enzyme deficiency interferes with the baby's ability to break
down medium chain fatty acids via beta oxidation. Her parents need to be given specific instructions on
what the baby can ingest. What is correct? - Answer-She will not be able to utilize adipose tissue for
ATP production as effectively as a baby without the disorder
Which of the following contributes to the development of ketoacidosis in a diabetic patient - Answer-A
reduction in citric acid cycle intermediates, which decreases the amount of oxaloacetate that acetyle-
CoA can combine with to enter the citric acid cycle
What describes a fatty acid? - Answer-C16H3202
Unsaturated fatty acids can have different arrangements of hydrogen atoms at the double bond
depending on whether the bonds are cis- or trans- configuration. A consequence of this : - Answer-fatty
acids with cis-configuration double bonds do not pack together well which lowers their melting point
What best describes fatty acid hydrogenation? - Answer-Hydrogenation converts some unsaturated
fatty acids into saturated fatty acids
