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Clinical Chemistry - Techniques, Principles, and Correlations by Bishop, Michael L. 6th Edition
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1. 1. Type II Diabetes mellitus: I. Juvenile onset II. Insulin Resistance III. Detectable C-peptide levels IV. Ketoacidosis V. Autoimmune 1/1 I and II II and III I, III and V II, III and IV IV and V: Feedback II and III Type 1 DM - Juvenile Onset DM - B-cell destruction - Absolute insulin deficiency - Ketosis prone diabetes - Low to negative C-peptide level- Autoantibodies • Islet cell autoantibodies • Insulin autoantibodies • Glutamic acid decarboxylase autoantibodies • Tyrosine phosphatase IA-2 and IA-2B autoantibodies
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