TEST BANK UNDERSTANDING PHARMACOLOGY:
ESSENTIALS FOR MEDICATION SAFETY, 2ND EDITION
WORKMAN & LACHARITY QUESTIONS WITH VERIFIED
SOLUTIONS
Absorption - CORRECT ANSWER-Movement of a drug from the outside of the body into the blood
stream.
Agonist - CORRECT ANSWER-An extrinsic drug that activates the receptor site of a cell and mimics the
actions of naturally occurring drugs.
Antagonist - CORRECT ANSWER-An extrinsic drug that blocks the receptor site of a cell, preventing the
naturally occurring substance from binding to the receptor.
Bioavailability - CORRECT ANSWER-The percentage of a drug dose that actually reaches the blood.
Black Box Warning - CORRECT ANSWER-A notice that a drug may produce serious or even life
threatening effects in some people in addition to its beneficial effects.
Cytoxic - CORRECT ANSWER-A drug action that is intended to kill a cell or organism.
Distribution - CORRECT ANSWER-The extent that a drug absorbed into the bloodstream spreads into the
three body water components.
Duration of Action - CORRECT ANSWER-The length of time a drug is present in the blood at or above the
level needed to produce an effect or response.
Extrinsic Drugs - CORRECT ANSWER-Drugs that are man made or derived from another species; not
made by the human body.
First pass loss - CORRECT ANSWER-Rapid inactivation or elimination of oral drugs as a result of liver
metabolism.
, Generic Name - CORRECT ANSWER-National and international public drug name created by the United
States Adopted NamesCouncil to indicate the usual use or chemical composition of a drug.
Half Life - CORRECT ANSWER-Time san needed for one half of a drug dose to be eliminated.
High Alert Drug - CORRECT ANSWER-A drug that has an increased risk of causing patient harm if it is used
in error.
Loading Dose - CORRECT ANSWER-The first dose of a drug that is larger than all subsequent doses of the
same drug; used when it takes more drug to reach steady state that it does to maintain it.
Mechanism of Action - CORRECT ANSWER-Exactly how, at the cellular level, a drug changes the activity
of a cell.
Minimum Effective
Concentration - CORRECT ANSWER-The smallest amount of drug necessary in the blood or target tissue
to result in a measurable intended action.
Percutaneous Route - CORRECT ANSWER-Movement of a drug from the outside of the body to the inside
through the skin or mucous membranes.
Pharmacodynamics - CORRECT ANSWER-Ways in which drugs work to change body function.
Pharmacokinetics - CORRECT ANSWER-How the body changes drugs; drug metabolism.
Physiologic Effects - CORRECT ANSWER-The change in body function as an income of the mechanism of
action off a drug.
Receptors - CORRECT ANSWER-Physical place on or in a cell where a drug can bind and interact.
ESSENTIALS FOR MEDICATION SAFETY, 2ND EDITION
WORKMAN & LACHARITY QUESTIONS WITH VERIFIED
SOLUTIONS
Absorption - CORRECT ANSWER-Movement of a drug from the outside of the body into the blood
stream.
Agonist - CORRECT ANSWER-An extrinsic drug that activates the receptor site of a cell and mimics the
actions of naturally occurring drugs.
Antagonist - CORRECT ANSWER-An extrinsic drug that blocks the receptor site of a cell, preventing the
naturally occurring substance from binding to the receptor.
Bioavailability - CORRECT ANSWER-The percentage of a drug dose that actually reaches the blood.
Black Box Warning - CORRECT ANSWER-A notice that a drug may produce serious or even life
threatening effects in some people in addition to its beneficial effects.
Cytoxic - CORRECT ANSWER-A drug action that is intended to kill a cell or organism.
Distribution - CORRECT ANSWER-The extent that a drug absorbed into the bloodstream spreads into the
three body water components.
Duration of Action - CORRECT ANSWER-The length of time a drug is present in the blood at or above the
level needed to produce an effect or response.
Extrinsic Drugs - CORRECT ANSWER-Drugs that are man made or derived from another species; not
made by the human body.
First pass loss - CORRECT ANSWER-Rapid inactivation or elimination of oral drugs as a result of liver
metabolism.
, Generic Name - CORRECT ANSWER-National and international public drug name created by the United
States Adopted NamesCouncil to indicate the usual use or chemical composition of a drug.
Half Life - CORRECT ANSWER-Time san needed for one half of a drug dose to be eliminated.
High Alert Drug - CORRECT ANSWER-A drug that has an increased risk of causing patient harm if it is used
in error.
Loading Dose - CORRECT ANSWER-The first dose of a drug that is larger than all subsequent doses of the
same drug; used when it takes more drug to reach steady state that it does to maintain it.
Mechanism of Action - CORRECT ANSWER-Exactly how, at the cellular level, a drug changes the activity
of a cell.
Minimum Effective
Concentration - CORRECT ANSWER-The smallest amount of drug necessary in the blood or target tissue
to result in a measurable intended action.
Percutaneous Route - CORRECT ANSWER-Movement of a drug from the outside of the body to the inside
through the skin or mucous membranes.
Pharmacodynamics - CORRECT ANSWER-Ways in which drugs work to change body function.
Pharmacokinetics - CORRECT ANSWER-How the body changes drugs; drug metabolism.
Physiologic Effects - CORRECT ANSWER-The change in body function as an income of the mechanism of
action off a drug.
Receptors - CORRECT ANSWER-Physical place on or in a cell where a drug can bind and interact.
