MSN 571 Pharmacology Week 1
Do APRNs have varied prescriptive practice restrictions? - ANS-Yes, at times based upon clinic
type, inpatient care, or rural designation.
Give examples of benzodiazepines included in the Beers Criteria. - ANS-Lorazepam and
diazepam.
Give examples of first-generation antihistamines included in the Beers Criteria. -
ANS-Diphenhydramine (Benadryl) and hydroxyzine.
Give examples of nonsteroidal anti-inflammatory drugs (NSAIDs) included in the Beers Criteria.
- ANS-Ibuprofen and naproxen.
Give examples of tricyclic antidepressants included in the Beers Criteria. - ANS-Amitriptyline
and nortriptyline.
How do age-related changes in total body water and serum albumin levels affect medication
distribution? - ANS-Age-related changes such as decreased total body water and low serum
albumin levels affect medication distribution, predisposing older adults to toxicity.
How does age-related acidity decline in the stomach affect medication absorption? -
ANS-Absorption of some medications is affected by age-related acidity declines in the stomach.
How does decreased liver mass and blood flow affect medication metabolism? -
ANS-Decreased liver mass and blood flow alter medication metabolism, making more
medication available in the bloodstream and predisposing older adults to toxicity.
How does increased elimination affect drug exposure during pregnancy? - ANS-Increased
elimination results in decreased drug exposure.
How does variable renal function due to normal aging affect the elimination of medications? -
ANS-Eliminating medications by the kidneys is affected by variable renal function due to normal
aging.
How has independent prescribing by advanced practice registered nurses (APRNs) been
addressed? - ANS-By individual states with considerable variation.
How is medication distribution altered in newborns and infants? - ANS-Increased total body
water, decreased body fat, and decreased levels of plasma proteins.
Do APRNs have varied prescriptive practice restrictions? - ANS-Yes, at times based upon clinic
type, inpatient care, or rural designation.
Give examples of benzodiazepines included in the Beers Criteria. - ANS-Lorazepam and
diazepam.
Give examples of first-generation antihistamines included in the Beers Criteria. -
ANS-Diphenhydramine (Benadryl) and hydroxyzine.
Give examples of nonsteroidal anti-inflammatory drugs (NSAIDs) included in the Beers Criteria.
- ANS-Ibuprofen and naproxen.
Give examples of tricyclic antidepressants included in the Beers Criteria. - ANS-Amitriptyline
and nortriptyline.
How do age-related changes in total body water and serum albumin levels affect medication
distribution? - ANS-Age-related changes such as decreased total body water and low serum
albumin levels affect medication distribution, predisposing older adults to toxicity.
How does age-related acidity decline in the stomach affect medication absorption? -
ANS-Absorption of some medications is affected by age-related acidity declines in the stomach.
How does decreased liver mass and blood flow affect medication metabolism? -
ANS-Decreased liver mass and blood flow alter medication metabolism, making more
medication available in the bloodstream and predisposing older adults to toxicity.
How does increased elimination affect drug exposure during pregnancy? - ANS-Increased
elimination results in decreased drug exposure.
How does variable renal function due to normal aging affect the elimination of medications? -
ANS-Eliminating medications by the kidneys is affected by variable renal function due to normal
aging.
How has independent prescribing by advanced practice registered nurses (APRNs) been
addressed? - ANS-By individual states with considerable variation.
How is medication distribution altered in newborns and infants? - ANS-Increased total body
water, decreased body fat, and decreased levels of plasma proteins.
