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UTMB 5355 Advanced Pathophysiology basic Questions and Answers 2

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UTMB 5355 Advanced Pathophysiology basic Questions and Answers 2 Which of the following are an active modulator of allergic reactions in the immune system? Eosinophils directs movement of cells along a chemical gradient attracting eosinophils and neutrophils to the site of inflammation. Chemotaxi

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UTMB 5355 Advanced Pathophysiology basic Questions and Answers 2




Which of the following are an active modulator of allergic reactions in the immune system?
✔✔Eosinophils



directs movement of cells along a chemical gradient attracting eosinophils and neutrophils to the site of
inflammation. ✔✔Chemotaxis



What are the functions of interferons? ✔✔Protect against viral infection, modulate inflammatory
response



Your patient has seasonal allergic rhinitis. Which type of hypersensitivity reaction is this? ✔✔Type 1



Your patient has diagnosis of Grave's disease. Which type of Hypersensitivity reaction is this? ✔✔Type 2



Which of the following is a type III hypersensitivity reaction? ✔✔Glomerulonephritis



Which of the following statement is true regarding Type IV Reactions? ✔✔The reaction is mediated by T
lymphocytes



Which of the following statements are true regarding exotoxins? ✔✔damage cell membranes, activate
second messengers, inhibit protein synthesis



immunity is produced by an individual after natural exposure to an antigen or after immunization
✔✔Active



immunity produces immunoglobulins that bind to antigens and neutralize their effects ✔✔Humoral



stimulates the proliferation of T cells and B cells during inflammation ✔✔Interleukins

, Catecholamines decrease which of the following immune system cells during chronic stress? ✔✔Natural
Killer cells



interfere with insulin signaling leading to insulin resistance in stress, obesity, and Type 2 Diabetes.
✔✔Pro-inflammatory cytokines



what type of immunity is produced when an immunoglobulin crosses the placenta? ✔✔Passive acquired



the normal microbiome ✔✔The body's surfaces are colonized with a variety of microorganisms,
Surfaces, such as skin and mucous membranes of eyes, upper and lower GI tracts, urethra and vagina
are colonized by a combination of bacteria and fungi that are unique to a particular location and
individual.



If immunocompromised the microbiome can lead to ✔✔opportunistic infections or loss of integrity of
the body surface areas.



Type 1 hypersensitivity example ✔✔seasonal rhinitis



Type 1 hypersensitivity ✔✔IgE mediated, binds to mast cell which causes release of histamine and other
inflammatory cytokines



Eosinphils are active in which hypersensitivity? ✔✔Type 1



Histamine binds to _ to cause allergic reaction ✔✔H1 receptors



Where are H1 receptors found? ✔✔smooth muscle, endothelium, bronchial lining, oral mucosa



act to prevent over reactions in the smooth muscle contractions brought on by histamine binding to H1
receptors ✔✔H2 receptors

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