MMSC491 Exam 3 Study Guide Questions and Answers 100% Pass

MMSC491 Exam 3 Study Guide Questions and Answers 100% Pass What is the most appropriate gene therapy for treating cancer? a. Repair of mutant gene b. Modifying disease cells c. Killing disease cells d. Gene augmentation - ANSWER-Killing disease cells How do cancer cells avoid chromosome destabilization due to their rapidly shortening telomeres? - ANSWER-They express telomerase In cancer cells, hypomethylation of DNA results in... - ANSWER-None of the above Which of the following databases contains descriptions of genomic, transcriptomic, and epigenetic changes in different types of tumors? - ANSWER-ICGC Copyright ©EMILLYCHARLOTE 2025 ACADEMIC YEAR, ALL RIGHTS RESERVED. Page 2/9 Which of the following discoveries in cancer research is a direct result of the advent of next-generation sequencing? - ANSWER-Extraordinary mutational diversity in tumors Which of the following is not a method of oncogene activation? - ANSWER-RAS/RAF pathway activation Which of the following is true about miRNA in cancer cells? - ANSWER-miRNAs have regulatory rules in apoptosis, cell-cycle control and DNA damage responses Which of the following can result from telomere instability in cancer cells? - ANSWER-The cell does not recognize the DNA as a chromosome and fuses it to another chromosome Which of the following regarding genome wide gene expression screens is false? - ANSWER-The hybridization probes bind to proteins within the cell Which of the following is defined as large numbers of chromosomal rearrangements are generated in what appear to be single catastrophic events? - ANSWER-Chromothripsis Copyright ©EMILLYCHARLOTE 2025 ACADEMIC YEAR, ALL RIGHTS RESERVED. Page 3/9 During a tumor removal surgery, the tumor is found to be a small mass of cells that has not affected any neighboring tissues. Several months later the patient is re-evaluated and is not showing any signs of recurrence. What kind of tumor did the patient most have? - ANSWER-Benign tumor Which of the following is NOT a characteristic of cancer cells? - ANSWER-Increased genome stability Which of the following correctly matches the treatment type with the definition? - ANSWER-Stratified medicine: dividing tumors into major subtypes that will have similar and predictable responses to drugs Programmed cell death is known as - ANSWER-Apoptosis What kind of tumor can occur in the single-layer or bilayer of epithelial tissue? - ANSWER-Adenoma