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NR 507 midterm Exam (Latest 2024/ 2025 Update) Advanced Pathophysiology | Questions and Verified Answers| 100% Correct |Grade A – Chamberlain

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NR 507 midterm Exam (Latest 2024/ 2025 Update) Advanced Pathophysiology | Questions and Verified Answers| 100% Correct |Grade A – Chamberlain

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NR 507 midterm Exam (Latest 2024/ 2025
Update) Advanced Pathophysiology |
Questions and Verified Answers| 100%
Correct |Grade A – Chamberlain

Hives (urticaria) are an example of a: - ANSWER
Type 1 hypersensitivity reaction.



Anaphylaxis is what type of reaction? - ANSWER
type 1 hypersensitivity



Which of the following are considered the "first responders" of the
innate immune system? - ANSWER
neutrophils



Allergic contact dermatitis is an example of what type of
hypersensitivity reaction. - ANSWER type
4 hypersensitivity reaction



Type 2 (Cytotoxic) hypersensitivity reactions are mediated by: -
ANSWER IgG or IgM

,Type 1 hypersensitivity reaction is mediated by - ANSWER
IgE



Allergic asthma is an example of - ANSWER
type 1 hypersensitivity reaction



type 2 hypersensitivity - ANSWER tissue
specific



Primary effector cells of type 2 - ANSWER
macrophages



Examples of type 2 reactions - ANSWER
drug allergies, hemolytic anemia, blood transfusion mismatch, allergies
against infectious agents



Type 2 causes - ANSWER The cell to be
destroyed by the antibody
Cell destruction through phagocytosis by macrophages
Damage to the cell by neutrophils triggering phagocytosis
Natural killer cells to release toxic substances that destroy the target cell
Malfunction of the cell without destruction

,Type 3 hypersensitivity reaction - ANSWER
antigen-antibody response



Where does the antibody bind to the antigen in type 3 response? -
ANSWER in blood or body fluids and then
circulates to tissue



Where does the antibody bind to the antigen in type 1, 2, and 4? -
ANSWER on cell surface



Primary effector cell in type 3 - ANSWER
neutrophils



example of type 3 reaction - ANSWER
serum sickness



type 4 hypersensitivity reaction - ANSWER
cell-mediated response



primary mediators of type 4 - ANSWER
lymphocytes and macrophages

, type 4 mediated by - ANSWER T
lymphocytes and do not use antibodies



example of type 4 - ANSWER localized
contact dermatitis (poison ivy)



Damage occurs with ABO incompatibility because: - ANSWER
Complement damages RBC membrane causing cell lysis.



Which of the following is the underlying pathology for hay fever? -
ANSWER mast cell degranulation



The diagnosis for an individual who presents to the office with sudden
swollen lips and eyes, shortness of breath and throat tightness after a bee
sting is: - ANSWER anaphylaxis



Which of the following assessment findings would be expected in a
patient who presents with urticaria? - ANSWER
Eosinophilia.

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