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NR507NP Midterm Questions & Answers

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Which of the following are considered the "first responders" of the innate immune system? - ANSWERSNeutrophils Hives (urticaria) are an example of a: - ANSWERSType I Hypersensitivity Reaction Allergic contact dermatitis is an example of ______________________ hypersensitivity reaction. - ANSWERSType IV Type 2 (Cytotoxic) hypersensitivity reactions are mediated by: - ANSWERSIgG or IgM Anaphylaxis is a __________________ hypersensitivity reaction. - ANSWERSType I Which of the following is the underlying pathology for hay fever? Formation of autoantibodies. Activation of complement. Destruction by T-cells. Mast cell degranulation. - ANSWERSMast Cell Degranulation Which of the following assessment findings would be expected in a patient who presents with urticaria? Eosinophilia. Decreased thyroid-stimulation hormone level. Thrombocytopenia. Leukopenia. - ANSWERSEosinophilia The diagnosis for an individual who presents to the office with sudden swollen lips and eyes, shortness of breath and throat tightness after a bee sting is: Anaphylaxis. Asthma. Angioedema. Reactive airway disease. - ANSWERSAnaphylaxis Damage occurs with ABO incompatibility because: Complement damages RBC membrane causing cell lysis. Mast cell degranulation. Autoantibodies specific for thyroid tissue impairs the receptors for TSH. Antigen/Antibody complexes attack the RBC. - ANSWERSComplement damages RBC membrane causing cell lysis Which is true about a primary immunodeficiency? It is the result of a single gene defect. It appears primarily in older adults. It is usually inherited. It is the result of multiple gene defects. - ANSWERSIt is the result of a single gene defect. _____________________________ is a predominant cause of secondary immune deficiencies worldwide. - ANSWERSMalnutrition An example of a secondary immunodeficiency is: Job Syndrome. Common Variable Immunodeficiency. Familial Mediterranean Fever. Pneumocystis Carinii. - ANSWERSPneumocystis Carinii. An example of a primary immunodeficiency is: Sinus Infection. Human Immunodeficiency virus. Pneumonia. Chronic Granulomatous Disease. - ANSWERSChronic Granulomatous Disease True or False: Cancer is a secondary immunodeficiency. - ANSWERSTrue Sinusitis is considered a primary immunodeficiency.? - ANSWERSFalse Select the best statement below that describes a primary immunodeficiency: Are less common and occur due to a defect on the development of the immune system. Conditions where the immune system becomes compromised because of something else. - ANSWERSAre less common and occur due to a defect on the development of the immune system. A patient with human immunodeficiency virus (HIV) was admitted to the acute care facility with difficulty breathing. He is diagnosed with Pneumocytis carinii. Pneumocystis carinii an example of: A primary immune disease. A secondary immune disease. - ANSWERSA secondary immune disease The major immune system change associated with Sjogren's Syndrome is: Autoantibodies and auto-reactive T-cells against apoptotic cells. Autoantibodies and auto-reactive T-cells and B-cells against joint-associated antigens. Autoantibodies and auto-reactive T-cells against brain antigens. Autoantibodies and auto-active T-cells against DNA and nucleoprotein antigens - ANSWERSAutoantibodies and auto-reactive T-cells against apoptotic cells. Which of the following findings can be used to diagnose Systemic Lupus Erythematosus (SLE)? Facial rash confined to the cheeks. Low back pain. Fever. Headache. - ANSWERSFacial rash confined to the cheeks. The ___________________________ test is positive in 90% of patients diagnosed with Systemic Lupus Erythematosus (SLE). - ANSWERSAntinuclear Antibody (ANA) A renal disease most often associated with autoimmunity is: Cystitis. Renal lithiasis. Urinary Tract Infection. Glomerulonephritis. - ANSWERSGlomerulonephritis. The presence of a low number of autoantibodies is an indicator that the individual will develop an autoimmune disease. True False - ANSWERSFalse The following immune components can be involved in autoimmune diseases: T-Cells, B-cells and autoantibodies. True False - ANSWERStrue Which of the following assessment findings would support a diagnosis of Rheumatoid Arthritis (RA)? Muscle weakness and ataxia. Inflammation in the salivary and lacrimal glands. A butterfly rash across the facial cheeks. Swollen metacarpophalangeal joints. - ANSWERSSwollen metacarpophalangeal joints. The presenting signs and symptoms of an autoimmune disease is similar across all autoimmune diseases. True False - ANSWERSFalse

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NR507NP Midterm Questions & Answers
Which of the following are considered the "first responders" of the innate immune
system? - ANSWERSNeutrophils

Hives (urticaria) are an example of a: - ANSWERSType I Hypersensitivity Reaction

Allergic contact dermatitis is an example of ______________________ hypersensitivity
reaction. - ANSWERSType IV

Type 2 (Cytotoxic) hypersensitivity reactions are mediated by: - ANSWERSIgG or IgM

Anaphylaxis is a __________________ hypersensitivity reaction. - ANSWERSType I

Which of the following is the underlying pathology for hay fever?

Formation of autoantibodies.
Activation of complement.
Destruction by T-cells.
Mast cell degranulation. - ANSWERSMast Cell Degranulation

Which of the following assessment findings would be expected in a patient who
presents with urticaria?

Eosinophilia.
Decreased thyroid-stimulation hormone level.
Thrombocytopenia.
Leukopenia. - ANSWERSEosinophilia

The diagnosis for an individual who presents to the office with sudden swollen lips and
eyes, shortness of breath and throat tightness after a bee sting is:

Anaphylaxis.
Asthma.
Angioedema.
Reactive airway disease. - ANSWERSAnaphylaxis

,Damage occurs with ABO incompatibility because:

Complement damages RBC membrane causing cell lysis.
Mast cell degranulation.
Autoantibodies specific for thyroid tissue impairs the receptors for TSH.
Antigen/Antibody complexes attack the RBC. - ANSWERSComplement damages RBC
membrane causing cell lysis

Which is true about a primary immunodeficiency?

It is the result of a single gene defect.
It appears primarily in older adults.
It is usually inherited.
It is the result of multiple gene defects. - ANSWERSIt is the result of a single gene
defect.

_____________________________ is a predominant cause of secondary immune
deficiencies worldwide. - ANSWERSMalnutrition

An example of a secondary immunodeficiency is:

Job Syndrome.
Common Variable Immunodeficiency.
Familial Mediterranean Fever.
Pneumocystis Carinii. - ANSWERSPneumocystis Carinii.

An example of a primary immunodeficiency is:

Sinus Infection.
Human Immunodeficiency virus.
Pneumonia.
Chronic Granulomatous Disease. - ANSWERSChronic Granulomatous Disease

True or False: Cancer is a secondary immunodeficiency. - ANSWERSTrue

Sinusitis is considered a primary immunodeficiency.? - ANSWERSFalse

Select the best statement below that describes a primary immunodeficiency:

Are less common and occur due to a defect on the development of the immune system.
Conditions where the immune system becomes compromised because of something
else. - ANSWERSAre less common and occur due to a defect on the development of
the immune system.

, A patient with human immunodeficiency virus (HIV) was admitted to the acute care
facility with difficulty breathing. He is diagnosed with Pneumocytis carinii. Pneumocystis
carinii an example of:

A primary immune disease.
A secondary immune disease. - ANSWERSA secondary immune disease

The major immune system change associated with Sjogren's Syndrome is:

Autoantibodies and auto-reactive T-cells against apoptotic cells.
Autoantibodies and auto-reactive T-cells and B-cells against joint-associated antigens.
Autoantibodies and auto-reactive T-cells against brain antigens.
Autoantibodies and auto-active T-cells against DNA and nucleoprotein antigens -
ANSWERSAutoantibodies and auto-reactive T-cells against apoptotic cells.

Which of the following findings can be used to diagnose Systemic Lupus Erythematosus
(SLE)?

Facial rash confined to the cheeks.
Low back pain.
Fever.
Headache. - ANSWERSFacial rash confined to the cheeks.

The ___________________________ test is positive in 90% of patients diagnosed with
Systemic Lupus Erythematosus (SLE). - ANSWERSAntinuclear Antibody (ANA)

A renal disease most often associated with autoimmunity is:
Cystitis.
Renal lithiasis.
Urinary Tract Infection.
Glomerulonephritis. - ANSWERSGlomerulonephritis.

The presence of a low number of autoantibodies is an indicator that the individual will
develop an autoimmune disease.
True
False - ANSWERSFalse

The following immune components can be involved in autoimmune diseases: T-Cells,
B-cells and autoantibodies.
True
False - ANSWERStrue

Which of the following assessment findings would support a diagnosis of Rheumatoid
Arthritis (RA)?
Muscle weakness and ataxia.
Inflammation in the salivary and lacrimal glands.

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