ANCC AGPCNP Practice Exam Latest
2024/2025 With Rationale (Complied From Real
Exam) Score A
The nurse practitioner is completing a health assessment on a 15-year-old
female patient who is in the office for her annual physical. The patient
reports feelings of hopelessness and sadness for several months, no
history of suicidal ideations, and a struggle with anorexia. The patient
scores an 11 on Beck's Depression Inventory. Which antidepressant will
the nurse practitioner prescribe?
a. Sertraline (Zoloft)
b. Lithium carbonate (Eskalith)
c. Bupropion (Wellbutrin)
d. Escitalopram (Lexapro)
d. Escitalopram [Lexapro]
Escitalopram is a safe antidepressant for an adolescent who has severe
depression and no history of suicidal ideations. Sertraline is not a safe
option for patients younger than 24 years of age because of increased risk
of suicidal ideation. Bupropion is an atypical antidepressant and is not a
first-line therapy for depression. It is contraindicated in patients with
anorexia nervosa. Lithium is indicated for patients with bipolar disorder.
,Which initial treatment will the nurse practitioner prescribe to a 23-year-
old female allergic to sulfa drugs who is diagnosed with acute cystitis?
a. Cephalexin (Keflex) 500 mg BID × 5 days
b. Ciprofloxacin (Cipro) 250 mg BID × 3 days
c. Nitrofurantoin (Macrobid) 100 mg BID × 5 days
d. Amoxicillin 500 mg BID × 5 days
c. Nitrofurantoin (Macrobid) 100 mg BID × 5 days
Nitrofurantoin can be safely administered to a patient with a sulfa allergy
to treat acute cystitis and is the first line of treatment. Cephalexin and
amoxicillin are beta-lactam antibiotics that can be prescribed for a patient
who has an allergy to sulfa and nitrofurantoin. A fluoroquinolone, such as
ciprofloxacin, is recommended for a patient who is allergic to sulfa and
beta-lactam drugs or has a sulfa allergy and a known resistance to beta-
lactam antibiotics.
A 68-year-old patient recently prescribed caridopa-levodopa (Sinemet)
tells the nurse practitioner that he has been bloated and experiencing
difficulty with bowel movements. Which medication will the nurse
practitioner consider incorporating into the treatment plan?
a. Senna
,b. Methylnaltrexone
c. Magnesium citrate
d. Polyethylene glycol
d. Polyethylene glycol
Levodopa, an antiparkinsonian drug, can cause constipation in an older
patient. The first-line treatment for the patient's constipation is osmotic
laxatives such as polyethylene glycol. Senna is a stimulant laxative that is
a second-line treatment for constipation in an older adult.
Methylnaltrexone is a peripherally acting mu-opioid antagonist that acts
on the gastrointestinal tract to decrease opioid-induced constipation.
Magnesium-based laxatives (e.g., magnesium citrate) taken over the long
term should be avoided because of the potential of toxicity.
A patient recently returned from a trip to Africa and is experiencing 10 to
12 loose stools every day. The patient takes metformin every morning and
otherwise is in good health. Which medication will the nurse practitioner
prescribe to treat the diarrhea?
a. Levofloxacin daily
b. Ofloxacin BID
c. Trimethoprim-sulfamethoxazole BID
d. Ciprofloxacin in a single dose
d. Ciprofloxacin in a single dose
, The patient most likely has traveler's diarrhea, given the history of a
recent return from another country. The patient's treatment should be
based on functional impact of symptoms and not frequency of symptoms,
which is not indicated in the question. The patient likely has moderate
acute traveler's diarrhea, which can be treated with loperamide as
monotherapy or with adjunctive antibiotic therapy. The patient is taking
metformin daily for diabetes, so risk of precipitating hypoglycemia is
lower than with other oral antidiabetic agents. Because it can be given in a
single dose, ciprofloxacin would be the appropriate choice for reducing
exposure and microbiome colonization disruption. Levofloxacin and
ofloxacin require one to three doses. Trimethoprim-sulfamethoxazole is a
sulfonamide and would be appropriate treatment for cyclosporiasis but
not giardiasis, which is the most common parasitic cause of traveler's
diarrhea.
A patient newly diagnosed with diabetes reports severe hives and swollen
lips after taking Bactrim for a bladder infection 2 months ago. Which of the
following statements is correct?
a. The patient cannot take any pills in the sulfonylurea class
b. The patient can take some of the pills in the sulfonylurea class
c. The patient can take any of the pills in the sulfonylurea class
d. None of the above
c. The patient can take any of the pills in the sulfonylurea class
2024/2025 With Rationale (Complied From Real
Exam) Score A
The nurse practitioner is completing a health assessment on a 15-year-old
female patient who is in the office for her annual physical. The patient
reports feelings of hopelessness and sadness for several months, no
history of suicidal ideations, and a struggle with anorexia. The patient
scores an 11 on Beck's Depression Inventory. Which antidepressant will
the nurse practitioner prescribe?
a. Sertraline (Zoloft)
b. Lithium carbonate (Eskalith)
c. Bupropion (Wellbutrin)
d. Escitalopram (Lexapro)
d. Escitalopram [Lexapro]
Escitalopram is a safe antidepressant for an adolescent who has severe
depression and no history of suicidal ideations. Sertraline is not a safe
option for patients younger than 24 years of age because of increased risk
of suicidal ideation. Bupropion is an atypical antidepressant and is not a
first-line therapy for depression. It is contraindicated in patients with
anorexia nervosa. Lithium is indicated for patients with bipolar disorder.
,Which initial treatment will the nurse practitioner prescribe to a 23-year-
old female allergic to sulfa drugs who is diagnosed with acute cystitis?
a. Cephalexin (Keflex) 500 mg BID × 5 days
b. Ciprofloxacin (Cipro) 250 mg BID × 3 days
c. Nitrofurantoin (Macrobid) 100 mg BID × 5 days
d. Amoxicillin 500 mg BID × 5 days
c. Nitrofurantoin (Macrobid) 100 mg BID × 5 days
Nitrofurantoin can be safely administered to a patient with a sulfa allergy
to treat acute cystitis and is the first line of treatment. Cephalexin and
amoxicillin are beta-lactam antibiotics that can be prescribed for a patient
who has an allergy to sulfa and nitrofurantoin. A fluoroquinolone, such as
ciprofloxacin, is recommended for a patient who is allergic to sulfa and
beta-lactam drugs or has a sulfa allergy and a known resistance to beta-
lactam antibiotics.
A 68-year-old patient recently prescribed caridopa-levodopa (Sinemet)
tells the nurse practitioner that he has been bloated and experiencing
difficulty with bowel movements. Which medication will the nurse
practitioner consider incorporating into the treatment plan?
a. Senna
,b. Methylnaltrexone
c. Magnesium citrate
d. Polyethylene glycol
d. Polyethylene glycol
Levodopa, an antiparkinsonian drug, can cause constipation in an older
patient. The first-line treatment for the patient's constipation is osmotic
laxatives such as polyethylene glycol. Senna is a stimulant laxative that is
a second-line treatment for constipation in an older adult.
Methylnaltrexone is a peripherally acting mu-opioid antagonist that acts
on the gastrointestinal tract to decrease opioid-induced constipation.
Magnesium-based laxatives (e.g., magnesium citrate) taken over the long
term should be avoided because of the potential of toxicity.
A patient recently returned from a trip to Africa and is experiencing 10 to
12 loose stools every day. The patient takes metformin every morning and
otherwise is in good health. Which medication will the nurse practitioner
prescribe to treat the diarrhea?
a. Levofloxacin daily
b. Ofloxacin BID
c. Trimethoprim-sulfamethoxazole BID
d. Ciprofloxacin in a single dose
d. Ciprofloxacin in a single dose
, The patient most likely has traveler's diarrhea, given the history of a
recent return from another country. The patient's treatment should be
based on functional impact of symptoms and not frequency of symptoms,
which is not indicated in the question. The patient likely has moderate
acute traveler's diarrhea, which can be treated with loperamide as
monotherapy or with adjunctive antibiotic therapy. The patient is taking
metformin daily for diabetes, so risk of precipitating hypoglycemia is
lower than with other oral antidiabetic agents. Because it can be given in a
single dose, ciprofloxacin would be the appropriate choice for reducing
exposure and microbiome colonization disruption. Levofloxacin and
ofloxacin require one to three doses. Trimethoprim-sulfamethoxazole is a
sulfonamide and would be appropriate treatment for cyclosporiasis but
not giardiasis, which is the most common parasitic cause of traveler's
diarrhea.
A patient newly diagnosed with diabetes reports severe hives and swollen
lips after taking Bactrim for a bladder infection 2 months ago. Which of the
following statements is correct?
a. The patient cannot take any pills in the sulfonylurea class
b. The patient can take some of the pills in the sulfonylurea class
c. The patient can take any of the pills in the sulfonylurea class
d. None of the above
c. The patient can take any of the pills in the sulfonylurea class
