Kaplan and Sadock's Chapter 12
Questions and Correct Answers Graded
A+
12.1. The Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR) states specifically that the
diagnosis ofdependencecanbeappliedtoeveryclassofsubstances except
A. anabolic steroids
B. caffeine
C. nicotine
D. nitrous oxide
E. none of the above - Answer: B. caffeine
FT is a 73-year old successful emeritus professor at a small liberal arts college in the Midwest. He was in
relative good health when he entered the hospital for an elective hernia repair. The brief history
contained no detailed notes of his drinking pattern and made no mention of his γ-glutamyltransferase
value of 55 U/L along with the mean corpuscular volume (MCV) of 93.5 μm3. Eight hours postsurgery,
the nursing staff noted an acute increase in the pulse rate to 110 beats/min, an increased in blood
pressure to 150/100 mm Hg, prominent diaphoresis, and a tremor to both hands, after which the
patient demonstrated a brief but intense grand mal convulsion. He awoke agitated and disoriented to
time, place, and person. A reevaluation of the history and an interview with the patient's wife
documented his alcohol dependence with a consumption of approximately six standard drinks per night.
Over the following 4 days, the p - Answer: A. Alcohol withdrawal delirium
Which of the following statements regarding cancer and alcohol use is correct?
A. Cancer may be caused by the immunosuppressive effects of ethanol.
B. Canceristhesecondleadingcauseofprematuredeath in alcoholics.
C. Increases in breast cancer have been noted with just two drinks per day.
D. Alcohol can be directly linked to cancers of mucous membranes.
E. All of the above - Answer: E. All of the above
12.4. Which of the following statements regarding alcohol's effect on sleep is false?
A. Heavy drinkers often awaken at night and have difficulty going back to sleep.
, B. Alcoholics tend to have more dreams later in the night.
C. Alcohol increases rapid eye movement (REM) sleep.
D. Alcohol can significantly impair normal sleep patterns.
E. Alcohol use tends to inhibit stage 4 sleep. - Answer: C. Alcohol increases rapid eye movement (REM)
sleep.
12.5. Acute PCP intoxication is not treated with
A. diazepam (Valium)
B. cranberry juice
C. phentolamine (Regitine)
D. phenothiazines
E. all of the above - Answer: D. phenothiazines
12.6. In distinguishing schizophrenia from amphetamineinduced toxic psychosis, the presence of which
of the following is most helpful?
A. tactile or visual hallucinations
B. paranoid delusions
C. intact orientation
D. clear consciousness
E. auditory hallucinations - Answer: A. tactile or visual hallucinations
12.7. The image in Figure 12.1 shows decreased dopamine type 2 (D2) receptor binding in the striatum
in drug users compared with normal control subjects. Which of the following types of substance
withdrawal is this pattern not typical of?
A. Alcohol
B. Cocaine
C. Methamphetamine
D. Opioids
E. All of the above - Answer: D. Opioids
Questions and Correct Answers Graded
A+
12.1. The Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR) states specifically that the
diagnosis ofdependencecanbeappliedtoeveryclassofsubstances except
A. anabolic steroids
B. caffeine
C. nicotine
D. nitrous oxide
E. none of the above - Answer: B. caffeine
FT is a 73-year old successful emeritus professor at a small liberal arts college in the Midwest. He was in
relative good health when he entered the hospital for an elective hernia repair. The brief history
contained no detailed notes of his drinking pattern and made no mention of his γ-glutamyltransferase
value of 55 U/L along with the mean corpuscular volume (MCV) of 93.5 μm3. Eight hours postsurgery,
the nursing staff noted an acute increase in the pulse rate to 110 beats/min, an increased in blood
pressure to 150/100 mm Hg, prominent diaphoresis, and a tremor to both hands, after which the
patient demonstrated a brief but intense grand mal convulsion. He awoke agitated and disoriented to
time, place, and person. A reevaluation of the history and an interview with the patient's wife
documented his alcohol dependence with a consumption of approximately six standard drinks per night.
Over the following 4 days, the p - Answer: A. Alcohol withdrawal delirium
Which of the following statements regarding cancer and alcohol use is correct?
A. Cancer may be caused by the immunosuppressive effects of ethanol.
B. Canceristhesecondleadingcauseofprematuredeath in alcoholics.
C. Increases in breast cancer have been noted with just two drinks per day.
D. Alcohol can be directly linked to cancers of mucous membranes.
E. All of the above - Answer: E. All of the above
12.4. Which of the following statements regarding alcohol's effect on sleep is false?
A. Heavy drinkers often awaken at night and have difficulty going back to sleep.
, B. Alcoholics tend to have more dreams later in the night.
C. Alcohol increases rapid eye movement (REM) sleep.
D. Alcohol can significantly impair normal sleep patterns.
E. Alcohol use tends to inhibit stage 4 sleep. - Answer: C. Alcohol increases rapid eye movement (REM)
sleep.
12.5. Acute PCP intoxication is not treated with
A. diazepam (Valium)
B. cranberry juice
C. phentolamine (Regitine)
D. phenothiazines
E. all of the above - Answer: D. phenothiazines
12.6. In distinguishing schizophrenia from amphetamineinduced toxic psychosis, the presence of which
of the following is most helpful?
A. tactile or visual hallucinations
B. paranoid delusions
C. intact orientation
D. clear consciousness
E. auditory hallucinations - Answer: A. tactile or visual hallucinations
12.7. The image in Figure 12.1 shows decreased dopamine type 2 (D2) receptor binding in the striatum
in drug users compared with normal control subjects. Which of the following types of substance
withdrawal is this pattern not typical of?
A. Alcohol
B. Cocaine
C. Methamphetamine
D. Opioids
E. All of the above - Answer: D. Opioids
