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FSHN 362-Exam 1 Questions With Correct Answers

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©BRIGHTSTARS EXAM SOLUTIONS 11/16/2024 10:16 AM 1 | P a g e FSHN 362-Exam 1 Questions With Correct Answers What is transcription and what is the mechanism that happens? - answerTranscription- process of DNA being copied out into RNA RNA polymerase binds to DNA, unwinds DNA, and forms single strand to serve as a template for post-transcription What is post-transcription and what does it do afterward? - answerPost-transcription is RNA getting turned into mRNA mRNA carries the genetic code to the cytoplasm to be translated for protein synthesis. Where does transcription/post-transcription occur? - answernucleus What is translation? - answerwhen mRNA is translated into an amino acid chain Where does translation occur? - answercytoplasm What is post-translation? - answerprocess of amino acid chains are modified into a mature protein What does tRNA and rRNA do in the post-translational process? - answertRNA- transports amino acids to ribosomes where proteins are synthesized rRNA- provides enzymes for protein synthesis How is Iodine a direct regulation of nutrient metabolism at the transcription level? - answerIodine stimulates the growth hormone How is LDL receptor synthesis an indirect transcriptional regulation? - answerWhen cholesterol goes down in the cell, it releases SRBP which goes to the DNA and increases transcription and translation to synthesize the LDL receptors so that cholesterol uptake can increase. ©BRIGHTSTARS EXAM SOLUTIONS 11/16/2024 10:16 AM 2 | P a g e In an iron deficiency, how does transferrin receptor mRNA and Ferritin mRNA post- transcriptionally regulate? - answerTransferrin receptor mRNA- is stabilized to increase transferrin receptor synthesis which blocks Ferritin mRNA translation and ferritin synthesis In an iron overload, how does transferrin receptor mRNA and Ferritin mRNA post- transcriptionally regulate? - answerTransferrin receptor mRNA is not stabilized, so it is degraded while ferritin mRNA is translated to increase ferritin synthesis How is insulin regulated post-translationally? - answerIn bovine proinsulin, amino acids are removed during its translation to insulin What is a genome? - answergenetic material within our cells containing complete set of instructions to make an organism Proper cell function is controlled by what 2 things? - answer1. Gene regulation 2. Enzyme regulation How does a fertilized egg differentiate into different cell types? - answerExpression of genes (on and off) In bacteria gene transcription, what is the area of the DNA that forms all the enzymes needed for synthesizing? - answerOperon What is the main difference between eukaryotic and bacterial cells? - answerEukaryotic cells have several transcription factors What does the repressor protein do? - answerPrevents attachment of RNA polymerase Ex: High tryptophan in the cell makes repressor protein active and blocks its synthesis What does the activator protein do? - answerHelps RNA polymerase bind to DNA which, initiates transcription Ex: turns on to synthesize enzymes to degrade sugars other than glucose What is epigenetics? - answerPhenotypic trait variations caused by external or environmental factors that switch genes on and off, not being caused by changes in the DNA sequence. Often occurs from addition or removal of methyl groups or chromatin modification. ©BRIGHTS

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©BRIGHTSTARS EXAM SOLUTIONS

11/16/2024 10:16 AM


FSHN 362-Exam 1 Questions With Correct
Answers


What is transcription and what is the mechanism that happens? - answer✔Transcription-
process of DNA being copied out into RNA


RNA polymerase binds to DNA, unwinds DNA, and forms single strand to serve as a template for
post-transcription

What is post-transcription and what does it do afterward? - answer✔Post-transcription is RNA
getting turned into mRNA
mRNA carries the genetic code to the cytoplasm to be translated for protein synthesis.

Where does transcription/post-transcription occur? - answer✔nucleus

What is translation? - answer✔when mRNA is translated into an amino acid chain

Where does translation occur? - answer✔cytoplasm

What is post-translation? - answer✔process of amino acid chains are modified into a mature
protein

What does tRNA and rRNA do in the post-translational process? - answer✔tRNA- transports
amino acids to ribosomes where proteins are synthesized
rRNA- provides enzymes for protein synthesis
How is Iodine a direct regulation of nutrient metabolism at the transcription level? -
answer✔Iodine stimulates the growth hormone

How is LDL receptor synthesis an indirect transcriptional regulation? - answer✔When
cholesterol goes down in the cell, it releases SRBP which goes to the DNA and increases
transcription and translation to synthesize the LDL receptors so that cholesterol uptake can
increase.

1|Page

, ©BRIGHTSTARS EXAM SOLUTIONS

11/16/2024 10:16 AM

In an iron deficiency, how does transferrin receptor mRNA and Ferritin mRNA post-
transcriptionally regulate? - answer✔Transferrin receptor mRNA- is stabilized to increase
transferrin receptor synthesis
which blocks
Ferritin mRNA translation and ferritin synthesis
In an iron overload, how does transferrin receptor mRNA and Ferritin mRNA post-
transcriptionally regulate? - answer✔Transferrin receptor mRNA is not stabilized, so it is
degraded while ferritin mRNA is translated to increase ferritin synthesis

How is insulin regulated post-translationally? - answer✔In bovine proinsulin, amino acids are
removed during its translation to insulin

What is a genome? - answer✔genetic material within our cells containing complete set of
instructions to make an organism

Proper cell function is controlled by what 2 things? - answer✔1. Gene regulation
2. Enzyme regulation

How does a fertilized egg differentiate into different cell types? - answer✔Expression of genes
(on and off)
In bacteria gene transcription, what is the area of the DNA that forms all the enzymes needed
for synthesizing? - answer✔Operon

What is the main difference between eukaryotic and bacterial cells? - answer✔Eukaryotic cells
have several transcription factors

What does the repressor protein do? - answer✔Prevents attachment of RNA polymerase
Ex: High tryptophan in the cell makes repressor protein active and blocks its synthesis

What does the activator protein do? - answer✔Helps RNA polymerase bind to DNA which,
initiates transcription
Ex: turns on to synthesize enzymes to degrade sugars other than glucose

What is epigenetics? - answer✔Phenotypic trait variations caused by external or environmental
factors that switch genes on and off, not being caused by changes in the DNA sequence. Often
occurs from addition or removal of methyl groups or chromatin modification.



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