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Milroy's disease - ANSWER ✔ -CONGENITAL lymphedema
-swelling in one or both legs that begins at birth
-Unable to form functional initial lymphatics
-Usually female
-Hereditary
Lymphedema Stage 0 Characteristics - ANSWER ✔ -No swelling
-Reduced TC and functional reserve
-Normal tissue consistency but US can reveal changes
-May have heaviness, achiness, warmth (Transient symptoms)
-Education/prevention
Lymphedema Stage 1 AKA - ANSWER ✔ Reversible Stage
Lymphedema Stage 1 Characteristics - ANSWER ✔ -Pitting edema that goes
down w/ elevation or treatment
,heavy, aching, fatigued
-Puffy
Goal-reduce edema
- negative or borderline stemmer sign
Lymphedema Stage 2 AKA - ANSWER ✔ Spontaneously Irreversible Stage
Lymphedema Stage 2 Characteristics - ANSWER ✔ -FIBROSIS
-Hard, lumpy, thickened, sludgy tissue
-Non-pitting.
-Edema that can be partially reduced or is irreversible
-Prone to infections
Lymphedema Stage 3 AKA - ANSWER ✔ Elephantiasis or
Sclerotic Lymphedema
Lymphedema Stage 3 Characteristics - ANSWER ✔ -SECONDARY SKIN
CHANGES
-Trigger is infection/cellulitis
-Skin folds/distorted shapes
-Severe skin changes- papillomatosis, hyperkeratosis, lichenification,
hyperpigmentation
Initial Lymphatics AKA - ANSWER ✔ Lymph Plexus
initial lymph collectors
,initial lymph vessels
Initial Lymphatics Characterisitics - ANSWER ✔ LOCATED: Just under epitheal
layer of epidermis and in the subendothelial lining of mucous membranes
-LARGER THAN BCs
-PICK UP LLs
-Irregular lumen with a discontinuous basement membrane of a single layer of flat
oak leaf in shape LECs
PRE-COLLECTORS - ANSWER ✔ -FOUND in- superficial portions of the
dermis & end at the collectors in the subcutaneous tissue
-CONNECT initial lymphatics to collectors
-Has some smooth muscle and some valves
-Has some open junctions
COLLECTORS - ANSWER ✔ Bring lymph to Lnn and trunks
HAVE DEVELOPED VALVES
Run parallel and bring lymph fluid distal to proximal
Deep collectors draining the deeper tissues & organs
Superficial collectors drain the skin or superficial tissue
, 3 LAYERS
Intima- endothelial cells and a basal membrane.
Media- Smooth muscle cells and elastic fibers.
Adventia- Collagen fibers and other cells (macrophages, neurons, and dendritic
cells)
Have open junctions in wall of the collectors allowing for a minimal amount of
solutes to escape,
like proteins.
Lymphatic Trunks - ANSWER ✔ Drain into larger vessels located in deep fascia
and or organs
Has valves and structure like collectors but with thicker media layer
6 main ones- gastrointestinal, lumbar, parasternal, supraclavicular, subclavian, and
jugular
Main two-thoracic and right lymphatic duct
Lymph Nodes - ANSWER ✔ FILTER the lymphatic fluid and activation,
differentiating, and proliferating lymphocytes.
THICKEN Lymph fluid
Has more afferent collectors coming in than efferent coming out of hilus.