Pharmacology HESI
-ase correct answers
Thrombolytic
-azepam correct answers
Benzodiazepine
-azine correct answers Antiemetic;
phenothiazide
-azole correct answers Proton Pump Inhibitor;
antifungal
-barbital correct answers
Barbiturate
-coxib correct answers Cox 2 enzyme
Blockers
-Cep/Cef correct answers Anti-
infectives
-caine correct answers
Anesthetics
-cillin correct answers
Penicillin
-cycline correct answers
Antibiotic
-dipine correct answers Calcium channel
blocker
-floxacin correct answers
antibiotic
-ipramine correct answers Tricyclic
antidepressant
-ine correct answers Reverse transcriptase inhibitors;
antihistamines
-kinase correct answers
Thrombolytic
-lone, pred- correct answers
Corticosteroid
-mab correct answers Monoclonal
antibiotics
-micin correct answers Antibiotic,
aminoglycoside
-navir correct answers Protease
inhibitor
nitr-, -nitr correct answers
Nitrate/vasodilator
-olol correct answers Beta
antagonist
,-oxin correct answers Cardiac
glycoside
-osin correct answers alpha
blocker
-parin correct answers
Anticoagulant
-proazole correct answers
PPIs
-phylline correct answers
Bronchodilator
-pril correct answers ACE
inhibitor
-statin correct answers Cholesterol lowering
agent
-sartan correct answers Angiotensin II
blocker
-sone correct answers Glucocorticoid;
corticosteroid
-stigmine correct answers
Cholinergics
-terol correct answers Beta 2
agonist
-thiazide correct answers
diuretic
-tidine correct answers
Antiulcer
-trophin correct answers Pituitary
hormone
-vir correct answers Anti-viral; protease
inhibitors
-zosin correct answers Alpha 1
antagonist
-zolam correct answers
Benzo/sedative
-zine correct answers
Antihistamine
Indications for anti-alzheimer's agents correct answers Management of
Alzheimer's
dementi
a
Mechanism of action for anti-alzheimer's agents correct answers Act by
increasing
amount the
of acetylcholine in the CNS by inhibiting
cholinesterase
May temporarily improve cognitive function and therefore improve
quality of life
Contraindications for anti-alzheimer's agents correct answers
Hypersensitivity
,Precautions for anti-alzheimer's agents correct answers Patients with a
historysyndrome'
sinus of "sick or other supraventricular cardiac conduction abnormalities
(may cause
bradycardi
a)
Cholinergic effects may result in adverse GI effects (nausea, vomiting,
diarrhea,
loss) and weight
may also increase gastric acid secretion resulting in GI bleeding,
especially
during concurrent NSAID
therapy
Other cholinergic effects may include urinary tract obstruction,
seizures, or
bronchospas
m
Interactions of Anti-alzheimer's agents correct answers Additive effects with
other drugs
having cholinergic
properties
May exaggerate the effects of succinylcholine-type muscle relaxation during
anesthesia
May decrease therapeutic effects of
anticholinergics
Assessment for Anti-alzheimer's agents correct answers Assess
cognitive function
(memory, attention, reasoning, language, ability to perform simple tasks)
throughout
therap
y
Monitor nausea, vomiting, anorexia, and weight loss. Notify HCP if these
side effects
occu
r
Patient teaching for Anti-alzheimer's agents correct answers Instruct
patient
caregiverand that medication should be taken as
directed
Advise patient and caregiver to notify health care professional if
nausea, vomiting,
anorexia, and weight loss
occur
Evaluation of Anti-Alzheimer's agents correct answers Temporary
improvement
cognitive in (memory, attention, reasoning, language, ability to
function
perform
tasks) in simple
patients with Alzheimer's
disease
Names of Anti-Alzheimerr's agents correct answers
Memantine
Rivastigmi
ne
Tacrin
e
Acetylcholinesterase inhibitor-
Donepezil
Cholinesterase inhibitor-
Galantamine
, Oral administration of medication correct answers Recommended that the
apical
be pulse
auscultated for 1 minute before any digitalis
preparation is given
Do not crush sustained-release
drugs
Indications for antianemics correct answers Prevention and treatment
of anemias
Mechanism of action for antianemics correct answers Iron (ferrous
fumarate, ferrous
gluconate, ferrous sulfate, iron dextran, iron sucrose, polysaccharide-iron
complex;
sodium ferric gluconate complex) is required for production of
hemoglobin,
necessary forwhich
oxygenis transport to
cells
Cyanobalamin and hydroxocobalamin (vitamin B12) and folic acid are
water-soluble
vitamins that are required for red blood cell
production
Darbepoetin, epoetin, and peginesatide stimulate production of red
blood cells
Contraindications for antianemics correct answers Undiagnosed
anemias
hemochromatosis, hemosiderosis, hemolytic
anemia (iron)
Uncontrolled hypertesnion (darbepoetin, epoetin, and
peginesatide)
Precautions for antianemics correct answers Use parenteral iron (iron
dextran, iron
sucrose, sodium ferric gluconate complex) cautiously in patients with a
history of allergy
Interactions for antianemics correct answers Oral iron can decrease the
absorption
tetracyclines,of fluoroquinolones, or
penicillamine
Vitamin E may impair the therapeutic response
to iron
Phenytoin and other anticonvulsants may decrease the absorption of
folic acid
Darbepoetin, epoetin, and peginesatide may increase the requirement
for heparin
during
hemodialysis
Assessment for antianemics correct answers Assess patient's nutritional
status and
dietary history to determine possible causes for anemia and need for
patient teaching
Implementation for antianemics correct answers Available in combination
with many
vitamins and
minerals
Patient teaching for antianemics correct answers Encourage patients to
comply
diet with
recommendations of HCP. Explain that the best source of vitamins and
minerals
a is
well-balanced diet with foods from the four basic
food groups
-ase correct answers
Thrombolytic
-azepam correct answers
Benzodiazepine
-azine correct answers Antiemetic;
phenothiazide
-azole correct answers Proton Pump Inhibitor;
antifungal
-barbital correct answers
Barbiturate
-coxib correct answers Cox 2 enzyme
Blockers
-Cep/Cef correct answers Anti-
infectives
-caine correct answers
Anesthetics
-cillin correct answers
Penicillin
-cycline correct answers
Antibiotic
-dipine correct answers Calcium channel
blocker
-floxacin correct answers
antibiotic
-ipramine correct answers Tricyclic
antidepressant
-ine correct answers Reverse transcriptase inhibitors;
antihistamines
-kinase correct answers
Thrombolytic
-lone, pred- correct answers
Corticosteroid
-mab correct answers Monoclonal
antibiotics
-micin correct answers Antibiotic,
aminoglycoside
-navir correct answers Protease
inhibitor
nitr-, -nitr correct answers
Nitrate/vasodilator
-olol correct answers Beta
antagonist
,-oxin correct answers Cardiac
glycoside
-osin correct answers alpha
blocker
-parin correct answers
Anticoagulant
-proazole correct answers
PPIs
-phylline correct answers
Bronchodilator
-pril correct answers ACE
inhibitor
-statin correct answers Cholesterol lowering
agent
-sartan correct answers Angiotensin II
blocker
-sone correct answers Glucocorticoid;
corticosteroid
-stigmine correct answers
Cholinergics
-terol correct answers Beta 2
agonist
-thiazide correct answers
diuretic
-tidine correct answers
Antiulcer
-trophin correct answers Pituitary
hormone
-vir correct answers Anti-viral; protease
inhibitors
-zosin correct answers Alpha 1
antagonist
-zolam correct answers
Benzo/sedative
-zine correct answers
Antihistamine
Indications for anti-alzheimer's agents correct answers Management of
Alzheimer's
dementi
a
Mechanism of action for anti-alzheimer's agents correct answers Act by
increasing
amount the
of acetylcholine in the CNS by inhibiting
cholinesterase
May temporarily improve cognitive function and therefore improve
quality of life
Contraindications for anti-alzheimer's agents correct answers
Hypersensitivity
,Precautions for anti-alzheimer's agents correct answers Patients with a
historysyndrome'
sinus of "sick or other supraventricular cardiac conduction abnormalities
(may cause
bradycardi
a)
Cholinergic effects may result in adverse GI effects (nausea, vomiting,
diarrhea,
loss) and weight
may also increase gastric acid secretion resulting in GI bleeding,
especially
during concurrent NSAID
therapy
Other cholinergic effects may include urinary tract obstruction,
seizures, or
bronchospas
m
Interactions of Anti-alzheimer's agents correct answers Additive effects with
other drugs
having cholinergic
properties
May exaggerate the effects of succinylcholine-type muscle relaxation during
anesthesia
May decrease therapeutic effects of
anticholinergics
Assessment for Anti-alzheimer's agents correct answers Assess
cognitive function
(memory, attention, reasoning, language, ability to perform simple tasks)
throughout
therap
y
Monitor nausea, vomiting, anorexia, and weight loss. Notify HCP if these
side effects
occu
r
Patient teaching for Anti-alzheimer's agents correct answers Instruct
patient
caregiverand that medication should be taken as
directed
Advise patient and caregiver to notify health care professional if
nausea, vomiting,
anorexia, and weight loss
occur
Evaluation of Anti-Alzheimer's agents correct answers Temporary
improvement
cognitive in (memory, attention, reasoning, language, ability to
function
perform
tasks) in simple
patients with Alzheimer's
disease
Names of Anti-Alzheimerr's agents correct answers
Memantine
Rivastigmi
ne
Tacrin
e
Acetylcholinesterase inhibitor-
Donepezil
Cholinesterase inhibitor-
Galantamine
, Oral administration of medication correct answers Recommended that the
apical
be pulse
auscultated for 1 minute before any digitalis
preparation is given
Do not crush sustained-release
drugs
Indications for antianemics correct answers Prevention and treatment
of anemias
Mechanism of action for antianemics correct answers Iron (ferrous
fumarate, ferrous
gluconate, ferrous sulfate, iron dextran, iron sucrose, polysaccharide-iron
complex;
sodium ferric gluconate complex) is required for production of
hemoglobin,
necessary forwhich
oxygenis transport to
cells
Cyanobalamin and hydroxocobalamin (vitamin B12) and folic acid are
water-soluble
vitamins that are required for red blood cell
production
Darbepoetin, epoetin, and peginesatide stimulate production of red
blood cells
Contraindications for antianemics correct answers Undiagnosed
anemias
hemochromatosis, hemosiderosis, hemolytic
anemia (iron)
Uncontrolled hypertesnion (darbepoetin, epoetin, and
peginesatide)
Precautions for antianemics correct answers Use parenteral iron (iron
dextran, iron
sucrose, sodium ferric gluconate complex) cautiously in patients with a
history of allergy
Interactions for antianemics correct answers Oral iron can decrease the
absorption
tetracyclines,of fluoroquinolones, or
penicillamine
Vitamin E may impair the therapeutic response
to iron
Phenytoin and other anticonvulsants may decrease the absorption of
folic acid
Darbepoetin, epoetin, and peginesatide may increase the requirement
for heparin
during
hemodialysis
Assessment for antianemics correct answers Assess patient's nutritional
status and
dietary history to determine possible causes for anemia and need for
patient teaching
Implementation for antianemics correct answers Available in combination
with many
vitamins and
minerals
Patient teaching for antianemics correct answers Encourage patients to
comply
diet with
recommendations of HCP. Explain that the best source of vitamins and
minerals
a is
well-balanced diet with foods from the four basic
food groups
