BIOD351
PHARMACOLOGY
Module 5
LATEST FINAL TEST REVIEW
Q&S
©2024/2025
,1. What is the primary physiological function of Type II
pneumocytes?
a) Gas exchange
b) Production of surfactant
c) Blood-air barrier maintenance
d) Removal of foreign particles
Correct Answer: b) Production of surfactant
Rationale: Type II pneumocytes are responsible for the
production and secretion of pulmonary surfactant which decreases
surface tension within the alveoli and prevents alveolar collapse.
2. Which of the following is a common cause of secondary
spontaneous pneumothorax?
a) Asthma
b) Chronic obstructive pulmonary disease (COPD)
c) Cystic fibrosis
d) All of the above
Correct Answer: d) All of the above
©2024/2025
, Rationale: Secondary spontaneous pneumothorax can occur due
to underlying lung diseases such as asthma, COPD, and cystic
fibrosis, which can lead to the development of blebs that rupture.
3. In the management of pulmonary arterial hypertension (PAH),
which class of medication is primarily used to target the
endothelin pathway?
a) Beta-blockers
b) Calcium channel blockers
c) Phosphodiesterase inhibitors
d) Endothelin receptor antagonists
Correct Answer: d) Endothelin receptor antagonists
Rationale: Endothelin receptor antagonists, such as bosentan,
are used in the treatment of PAH to block the effects of
endothelin-1, thereby reducing pulmonary vascular resistance.
4. A 65-year-old patient with a history of smoking presents with a
cough and weight loss. A CT scan shows a mass in the right upper
lobe with hilar lymphadenopathy. What is the most likely
diagnosis?
a) Tuberculosis
b) Lung abscess
c) Bronchogenic carcinoma
d) Pulmonary embolism
©2024/2025
, Correct Answer: c) Bronchogenic carcinoma
Rationale: The patient's history and radiographic findings are
suggestive of bronchogenic carcinoma, the most common type of
primary lung cancer, often associated with smoking.
5. Which of the following is not a typical feature of interstitial
lung disease (ILD)?
a) Clubbing
b) Chronic dry cough
c) Wheezing
d) Dyspnea on exertion
Correct Answer: c) Wheezing
Rationale: Wheezing is not a typical feature of ILD. ILD usually
presents with non-specific symptoms such as chronic dry cough,
dyspnea on exertion, and clubbing.
6. What is the mechanism of action of tiotropium in the treatment
of COPD?
a) It is a short-acting beta-agonist.
b) It is a long-acting muscarinic antagonist.
c) It is an inhaled corticosteroid.
d) It is a leukotriene receptor antagonist.
©2024/2025
PHARMACOLOGY
Module 5
LATEST FINAL TEST REVIEW
Q&S
©2024/2025
,1. What is the primary physiological function of Type II
pneumocytes?
a) Gas exchange
b) Production of surfactant
c) Blood-air barrier maintenance
d) Removal of foreign particles
Correct Answer: b) Production of surfactant
Rationale: Type II pneumocytes are responsible for the
production and secretion of pulmonary surfactant which decreases
surface tension within the alveoli and prevents alveolar collapse.
2. Which of the following is a common cause of secondary
spontaneous pneumothorax?
a) Asthma
b) Chronic obstructive pulmonary disease (COPD)
c) Cystic fibrosis
d) All of the above
Correct Answer: d) All of the above
©2024/2025
, Rationale: Secondary spontaneous pneumothorax can occur due
to underlying lung diseases such as asthma, COPD, and cystic
fibrosis, which can lead to the development of blebs that rupture.
3. In the management of pulmonary arterial hypertension (PAH),
which class of medication is primarily used to target the
endothelin pathway?
a) Beta-blockers
b) Calcium channel blockers
c) Phosphodiesterase inhibitors
d) Endothelin receptor antagonists
Correct Answer: d) Endothelin receptor antagonists
Rationale: Endothelin receptor antagonists, such as bosentan,
are used in the treatment of PAH to block the effects of
endothelin-1, thereby reducing pulmonary vascular resistance.
4. A 65-year-old patient with a history of smoking presents with a
cough and weight loss. A CT scan shows a mass in the right upper
lobe with hilar lymphadenopathy. What is the most likely
diagnosis?
a) Tuberculosis
b) Lung abscess
c) Bronchogenic carcinoma
d) Pulmonary embolism
©2024/2025
, Correct Answer: c) Bronchogenic carcinoma
Rationale: The patient's history and radiographic findings are
suggestive of bronchogenic carcinoma, the most common type of
primary lung cancer, often associated with smoking.
5. Which of the following is not a typical feature of interstitial
lung disease (ILD)?
a) Clubbing
b) Chronic dry cough
c) Wheezing
d) Dyspnea on exertion
Correct Answer: c) Wheezing
Rationale: Wheezing is not a typical feature of ILD. ILD usually
presents with non-specific symptoms such as chronic dry cough,
dyspnea on exertion, and clubbing.
6. What is the mechanism of action of tiotropium in the treatment
of COPD?
a) It is a short-acting beta-agonist.
b) It is a long-acting muscarinic antagonist.
c) It is an inhaled corticosteroid.
d) It is a leukotriene receptor antagonist.
©2024/2025
