NR 507 midterm
Hives (urticaria) are an example of a: - Answer-Type 1 hypersensitivity reaction.
Anaphylaxis is what type of reaction? - Answer-type 1 hypersensitivity
Which of the following are considered the "first responders" of the innate immune system? - Answer-
neutrophils
Allergic contact dermatitis is an example of what type of
hypersensitivity reaction. - Answer-type 4 hypersensitivity reaction
Type 2 (Cytotoxic) hypersensitivity reactions are mediated by: - Answer-IgG or IgM
Type 1 hypersensitivity reaction is mediated by - Answer-IgE
Allergic asthma is an example of - Answer-type 1 hypersensitivity reaction
type 2 hypersensitivity - Answer-tissue specific
,Primary effector cells of type 2 - Answer-macrophages
Examples of type 2 reactions - Answer-drug allergies, hemolytic anemia, blood transfusion mismatch,
allergies against infectious agents
Type 2 causes - Answer-The cell to be destroyed by the antibody
Cell destruction through phagocytosis by macrophages
Damage to the cell by neutrophils triggering phagocytosis
Natural killer cells to release toxic substances that destroy the target cell
Malfunction of the cell without destruction
Type 3 hypersensitivity reaction - Answer-antigen-antibody response
Where does the antibody bind to the antigen in type 3 response? - Answer-in blood or body fluids and
then circulates to tissue
Where does the antibody bind to the antigen in type 1, 2, and 4? - Answer-on cell surface
Primary effector cell in type 3 - Answer-neutrophils
example of type 3 reaction - Answer-serum sickness
type 4 hypersensitivity reaction - Answer-cell-mediated response
primary mediators of type 4 - Answer-lymphocytes and macrophages
, type 4 mediated by - Answer-T lymphocytes and do not use antibodies
example of type 4 - Answer-localized contact dermatitis (poison ivy)
Damage occurs with ABO incompatibility because: - Answer-Complement damages RBC membrane
causing cell lysis.
Which of the following is the underlying pathology for hay fever? - Answer-mast cell degranulation
The diagnosis for an individual who presents to the office with sudden swollen lips and eyes, shortness
of breath and throat tightness after a bee sting is: - Answer-anaphylaxis
Which of the following assessment findings would be expected in a patient who presents with urticaria?
- Answer-Eosinophilia.
An example of a primary immunodeficiency is: - Answer-Chronic Granulomatous Disease.
what is a predominant cause of secondary immune deficiencies worldwide. - Answer-Malnutrition
Which of the following is an autoimmune disease? - Answer-Systemic Lupus Erythematosus (SLE).
Which is true about a primary immunodeficiency? - Answer-It is the result of a single gene defect.
(genetics)
Examples of secondary immunodeficiency - Answer-HIV, cancer
Hives (urticaria) are an example of a: - Answer-Type 1 hypersensitivity reaction.
Anaphylaxis is what type of reaction? - Answer-type 1 hypersensitivity
Which of the following are considered the "first responders" of the innate immune system? - Answer-
neutrophils
Allergic contact dermatitis is an example of what type of
hypersensitivity reaction. - Answer-type 4 hypersensitivity reaction
Type 2 (Cytotoxic) hypersensitivity reactions are mediated by: - Answer-IgG or IgM
Type 1 hypersensitivity reaction is mediated by - Answer-IgE
Allergic asthma is an example of - Answer-type 1 hypersensitivity reaction
type 2 hypersensitivity - Answer-tissue specific
,Primary effector cells of type 2 - Answer-macrophages
Examples of type 2 reactions - Answer-drug allergies, hemolytic anemia, blood transfusion mismatch,
allergies against infectious agents
Type 2 causes - Answer-The cell to be destroyed by the antibody
Cell destruction through phagocytosis by macrophages
Damage to the cell by neutrophils triggering phagocytosis
Natural killer cells to release toxic substances that destroy the target cell
Malfunction of the cell without destruction
Type 3 hypersensitivity reaction - Answer-antigen-antibody response
Where does the antibody bind to the antigen in type 3 response? - Answer-in blood or body fluids and
then circulates to tissue
Where does the antibody bind to the antigen in type 1, 2, and 4? - Answer-on cell surface
Primary effector cell in type 3 - Answer-neutrophils
example of type 3 reaction - Answer-serum sickness
type 4 hypersensitivity reaction - Answer-cell-mediated response
primary mediators of type 4 - Answer-lymphocytes and macrophages
, type 4 mediated by - Answer-T lymphocytes and do not use antibodies
example of type 4 - Answer-localized contact dermatitis (poison ivy)
Damage occurs with ABO incompatibility because: - Answer-Complement damages RBC membrane
causing cell lysis.
Which of the following is the underlying pathology for hay fever? - Answer-mast cell degranulation
The diagnosis for an individual who presents to the office with sudden swollen lips and eyes, shortness
of breath and throat tightness after a bee sting is: - Answer-anaphylaxis
Which of the following assessment findings would be expected in a patient who presents with urticaria?
- Answer-Eosinophilia.
An example of a primary immunodeficiency is: - Answer-Chronic Granulomatous Disease.
what is a predominant cause of secondary immune deficiencies worldwide. - Answer-Malnutrition
Which of the following is an autoimmune disease? - Answer-Systemic Lupus Erythematosus (SLE).
Which is true about a primary immunodeficiency? - Answer-It is the result of a single gene defect.
(genetics)
Examples of secondary immunodeficiency - Answer-HIV, cancer
