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Exam (elaborations)

AADE Practice Test Exam Questions with 100% correct answers 2024

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AADE Practice Test Exam Questions with 100% correct answers

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AADE Practice Test Exam Questions
with 100% correct answers

62-year-oldipatientiwithitypei2idiabetesihasinoticediai30-
poundiweightigainioveritheipasti2iyears.iWhichiofitheifollowingidrugsiw
ouldimostilikelyiworseniheriweightigain?
Pramlintide
Exenatide
Rosiglitazone
Saxagliptini-iCorrectiAnswer-Ci-
iRosiglitazoneiisicorrect.iThiazolidinedionesi(pioglitazoneiandirosiglitaz

one)iactivateiPPAR-
gammaireceptorsiinitheibody.iActivationiofitheseireceptorsiresultsiinimo
bilizationiofivisceralifatiandipromotesidepositioniinisubcutaneousiadipo
seitissue.iPramlintideiandiexenatidei(AnswersiAiandiB)itenditoipromotei
weightiloss,iwhileisaxagliptini(AnsweriD)iisiweightineutral.


Ai62-year-
oldimaniwithitypei2idiabetesiandichronicikidneyidiseaseipresentsiforima
nagementiofihisidiabetes.iRecentilaboratoryivaluesiincludeitheifollowin
g:iA1Ci7.8%,iserumicreatininei2.3img/dL.iWhichiofitheifollowingiDPP-
4iinhibitorsimostiappropriateiforithisipatient?
Sitagliptin
Saxagliptin
Linagliptin

, Alogliptini-iCorrectiAnswer-Ci-
iLinagliptiniisicorrect.iLinagliptiniisitheionlyiagentiinitheiDPP-

4iinhibitoriclassithatidoesinotirequireidoseireductioniinipatientsiwithiren
aliimpairment.iSitagliptini(AnsweriA)iandiSaxagliptini(AnsweriB)irequirei
doseireductionsiwithiCrCli<50mL/min.iAlogliptini(AnsweriD)irequiresido
seireductioniwithiCrCli<60mL/min.


Ai35-year-oldipatientiwithitypei2idiabetesipresentsiforifollow-
upiofiheriglycemicicontrol.iHericurrentimedicationsiinclude:imetformini
1gitwiceidailyiandiglarginei46iunitsiatibedtimeiwithiairecentiA1Ciofi7.7%i(
goali<7%).iSheieatsiaigranolaibariforibreakfast,ihasiaisandwichiandiwater
iatilunch,itheniailargeieveningimeal.iSheideniesisymptomsiofihypoglyce

mia.iSheiweighsi156ipoundsi(BMIi26ikg/m^2)iandiheriaverageipreprandi
aliself-
monitoredibloodiglucoseilevelsiare:i152img/dLiati8AM,i160img/dLiatino
on,i146img/dLiati6iPM,iandi220img/dLiati10iPM.iHeriprovideridecidesitoi
startiglulisineibeforeitheieveningimeali(ati6iPM).iWhichiofitheifollowingi
wouldibeitheimostiappropriateirecommendationiforithisipatient?
1iunit
5iunits
15iunits
20iunitsi-iCorrectiAnswer-Bi-
i5iunitsiisicorrect.iBothitheiADAiandiAACEiguidelinesirecommendiaddingi

bolusiinsuliniatiaidoseiofieitheri10%iofitheicurrentibasalidose,iori0.1iunits
/kg,iori5iunits.iSubsequentidoseiadjustmentsicanibeimadeiini1itoi2iunitiin
crementsiori10%itoi15%iofitheidose.

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