NAPLEX ANTIBIOTICS
what is the absorption of itraconazole and ketoconazole dependent on? -
ANSWERS-pH - increased pH causes decreased absorption
avoid using with antacids, H2RAs, PPIs
which antifungal is the DOC for Aspergillus? - ANSWERS-voriconazole
what are some drugs that voriconazole is contraindicated with? - ANSWERS-
barbiturates
carbamazepine
rifampin
st. john's wort
what are the echinocandins? - ANSWERS-caspofungin (Cancidas)
micafungin (Mycamine)
anidulafungin (Eraxis)
main SE of the echinocandins? - ANSWERS-increased LFTs
dosing for micafungin (Mycamine)? - ANSWERS-candidemia: 100 mg IV daily
,esophageal candidiasis: 150 mg IV daily over sixty minutes
treatment for pulmonary Aspergillus? - ANSWERS-Voriconazole 6 mg/kg IV Q12
on day 1, then 4 mg/kg
treatment for bloodstream Candida albicans? - ANSWERS-fluconazole,
caspofungin, micafungin, anidulafungin
treatment duration for Candida albicans? - ANSWERS-2 weeks from first (-) blood
culture
treatment for oral candidiasis (thrush)? - ANSWERS-clotrimazole troches
nystatin suspension
PO fluconazole
how long do you treat thrush? - ANSWERS-1-2 weeks
how long do you treat esophageal candidiasis? - ANSWERS-2-3 weeks
what are neuraminidase inhibitors used for? - ANSWERS-influenza
oseltamivir brand name? - ANSWERS-Tamiflu
,SE of oseltamivir? - ANSWERS-vomiting
rhinorrhea
dyspepsia
URTI
rare: confusion, delirium, hallucinations, self-injury
brand name of zanamivir? - ANSWERS-Relenza
warning for Relenza? - ANSWERS-bronchospasm risk (don't use with any
breathing problems)
what is main difference between HSV-1 and HSV-2? - ANSWERS-HSV-1:
oropharyngeal disease
HSV-2: genital disease
brand name for acyclovir? - ANSWERS-Zovirax
brand name for the shingles vaccine? - ANSWERS-Zostavax
treatment options for west nile virus? - ANSWERS-acyclovir (Zovirax)
valacyclovir (Valtrex)
, *best treatment is prevention
important counseling point for all B-lactams? - ANSWERS-potential to cause rash
should amoxicillin be refrigerated? - ANSWERS-YES (and Augmentin)
what condition should quinolones be avoided in? - ANSWERS-seizure history
what can levaquin do to INR? - ANSWERS-increase it
what can levaquin do to blood sugar if used with other DM meds? - ANSWERS-
decrease it
brand name for doxycycline? - ANSWERS-Doryx
can cause photosensitivity
drink plenty of fluids while taking
take 2 hours before or 4 hours after antacids, vitamins, mg, ca
Erythromycin (EES) - ANSWERS-chew the tablet thoroughly before swallowing
can take with food or milk for nausea
what is the absorption of itraconazole and ketoconazole dependent on? -
ANSWERS-pH - increased pH causes decreased absorption
avoid using with antacids, H2RAs, PPIs
which antifungal is the DOC for Aspergillus? - ANSWERS-voriconazole
what are some drugs that voriconazole is contraindicated with? - ANSWERS-
barbiturates
carbamazepine
rifampin
st. john's wort
what are the echinocandins? - ANSWERS-caspofungin (Cancidas)
micafungin (Mycamine)
anidulafungin (Eraxis)
main SE of the echinocandins? - ANSWERS-increased LFTs
dosing for micafungin (Mycamine)? - ANSWERS-candidemia: 100 mg IV daily
,esophageal candidiasis: 150 mg IV daily over sixty minutes
treatment for pulmonary Aspergillus? - ANSWERS-Voriconazole 6 mg/kg IV Q12
on day 1, then 4 mg/kg
treatment for bloodstream Candida albicans? - ANSWERS-fluconazole,
caspofungin, micafungin, anidulafungin
treatment duration for Candida albicans? - ANSWERS-2 weeks from first (-) blood
culture
treatment for oral candidiasis (thrush)? - ANSWERS-clotrimazole troches
nystatin suspension
PO fluconazole
how long do you treat thrush? - ANSWERS-1-2 weeks
how long do you treat esophageal candidiasis? - ANSWERS-2-3 weeks
what are neuraminidase inhibitors used for? - ANSWERS-influenza
oseltamivir brand name? - ANSWERS-Tamiflu
,SE of oseltamivir? - ANSWERS-vomiting
rhinorrhea
dyspepsia
URTI
rare: confusion, delirium, hallucinations, self-injury
brand name of zanamivir? - ANSWERS-Relenza
warning for Relenza? - ANSWERS-bronchospasm risk (don't use with any
breathing problems)
what is main difference between HSV-1 and HSV-2? - ANSWERS-HSV-1:
oropharyngeal disease
HSV-2: genital disease
brand name for acyclovir? - ANSWERS-Zovirax
brand name for the shingles vaccine? - ANSWERS-Zostavax
treatment options for west nile virus? - ANSWERS-acyclovir (Zovirax)
valacyclovir (Valtrex)
, *best treatment is prevention
important counseling point for all B-lactams? - ANSWERS-potential to cause rash
should amoxicillin be refrigerated? - ANSWERS-YES (and Augmentin)
what condition should quinolones be avoided in? - ANSWERS-seizure history
what can levaquin do to INR? - ANSWERS-increase it
what can levaquin do to blood sugar if used with other DM meds? - ANSWERS-
decrease it
brand name for doxycycline? - ANSWERS-Doryx
can cause photosensitivity
drink plenty of fluids while taking
take 2 hours before or 4 hours after antacids, vitamins, mg, ca
Erythromycin (EES) - ANSWERS-chew the tablet thoroughly before swallowing
can take with food or milk for nausea
