MCB*2050 -
Topic 2 with
100% correct
answers 2025
Structural Genomics - answer - the study of gene structure
- genome mapping and sequencing
Comparative Genomics - answer - the study of genome evolution
- the comparison of genomes of different organisms
Functional Genomics - answer - the study of gene function
- analysis of the transcriptome and the proteome
- uses the information from genome sequencing to describe gene and
protein functions and interactions
Synthetic Genomics - answer - uses information from genome sequencing
to create new or modified organisms
Genomics - answer study of the "genome", the entire DNA genetic
material of an organism.
, Metagenomics - answer study of aggregate genomes from a complex of
organisms (e.g. from a gut microbiome)
Transcriptomics - answer study of the "transcriptome", all RNAs (e.gs.
tRNAs, rRNAs, snRNAs, microRNAs, mRNAs) expressed in a cell
Proteomics - answer study of the "proteome", all the proteins of an
organism and their interactions
Metabolomics - answer study of the "metabolome", all metabolic
pathways and intermediaries in an organism
Interactomics - answer study of the "interactome", all interactions, (e.g.
protein- protein, protein-nucleic acid, protein-ligand) of an organism
Cytological map - answer banding pattern of stained chromosomes
- microscopy of chromosome, staining bands, e.g. Giemsa (G) or
quinacrine (Q) differential staining
Genetic map - answer based on the use of genetic techniques to
construct maps showing the relative positions of genes and other
sequence features in the genome.
- cross-breeding or pedigree analysis to determine recombination
frequencies (linkage analysis)
relative position of genes, RFLP, STR, VNTR based on linkage studies
(recombination frequency). About 1 Mb (centi- Morgans) apart.
Physical map - answer molecular biology techniques are used to arrange
sequence features on a linear map.
Topic 2 with
100% correct
answers 2025
Structural Genomics - answer - the study of gene structure
- genome mapping and sequencing
Comparative Genomics - answer - the study of genome evolution
- the comparison of genomes of different organisms
Functional Genomics - answer - the study of gene function
- analysis of the transcriptome and the proteome
- uses the information from genome sequencing to describe gene and
protein functions and interactions
Synthetic Genomics - answer - uses information from genome sequencing
to create new or modified organisms
Genomics - answer study of the "genome", the entire DNA genetic
material of an organism.
, Metagenomics - answer study of aggregate genomes from a complex of
organisms (e.g. from a gut microbiome)
Transcriptomics - answer study of the "transcriptome", all RNAs (e.gs.
tRNAs, rRNAs, snRNAs, microRNAs, mRNAs) expressed in a cell
Proteomics - answer study of the "proteome", all the proteins of an
organism and their interactions
Metabolomics - answer study of the "metabolome", all metabolic
pathways and intermediaries in an organism
Interactomics - answer study of the "interactome", all interactions, (e.g.
protein- protein, protein-nucleic acid, protein-ligand) of an organism
Cytological map - answer banding pattern of stained chromosomes
- microscopy of chromosome, staining bands, e.g. Giemsa (G) or
quinacrine (Q) differential staining
Genetic map - answer based on the use of genetic techniques to
construct maps showing the relative positions of genes and other
sequence features in the genome.
- cross-breeding or pedigree analysis to determine recombination
frequencies (linkage analysis)
relative position of genes, RFLP, STR, VNTR based on linkage studies
(recombination frequency). About 1 Mb (centi- Morgans) apart.
Physical map - answer molecular biology techniques are used to arrange
sequence features on a linear map.
