Questions and CORRECT Answers
ANOVA assumptions - CORRECT ANSWER- ✔✔-Normality: normally distributed
-Homogeneity of variance: error variation about treatment means are similar
-Additivity: that an additive model is appropriate
How would you determine the optimum number of animals for a research trial? - CORRECT
ANSWER- ✔✔A power analysis can be used to estimate the minimum sample size required
for an experiment, given a desired significance level, effect size, and statistical power.
The 3Rs - CORRECT ANSWER- ✔✔Replacement: use alternative methods that do not
require live animals
Reduction: using most appropriate number of animals for each project
Refinement: minimizing suffering and improving animal welfare
Randomized complete block design - CORRECT ANSWER- ✔✔each block has an equal and
complete number of treatments, which are randomly distributed within each block
Completely randomized design - CORRECT ANSWER- ✔✔the treatments are assigned to all
the experimental units completely by chance
3 principles of experimental design - CORRECT ANSWER- ✔✔replication - each treatment
tested on more than 1 experimental unit
randomization - allocation of treatments to express units is random
local control - more than one treatment