MLT ASCP Practice Questions with
correct answers
A hemoglobin molecule is composed of:
a. One heme molecule and four globin chains
b. Ferrous iron, protoporphyrin IX, and a globin chain
c. Protoporphyrin IX and four globin chains
d. Four heme molecules and four globin chains - CORRECT ANSWERS-d. Four heme
molecules and four globin chains
A patient has a hemoglobin level of 8.0 g/dL. According to the rule of three, what is the expected
range for the hematocrit?
a. 21% to 24%
b. 23.7% to 24.3%
c. 24% to 27%
d. 21% to 27% - CORRECT ANSWERS-d. 21% to 27%
All of the following cells are normally seen in CSF, serous fluids, and synovial fluids except:
a. Lining cells
b. Neutrophils
c. Lymphocytes
d. Monocytes/histiocytes (macrophages) - CORRECT ANSWERS-b. Neutrophils
An increase in which one of the following suggests a shortened life span of RBCs and hemolytic
anemia?
,a. Hemoglobin
b. Hematocrit
c. Reticulocyte count
d. Red cell distribution width - CORRECT ANSWERS-`c. Reticulocyte count
Basophils and mast cells have high-affinity surface receptors for which immunoglobulin?
a. A
b. D
c. E
d. G - CORRECT ANSWERS-c. E
Common clinical symptoms of anemia include:
a. Splenomegaly
b. Shortness of breath and fatigue
c. Chills and fever
d. Jaundice and enlarged lymph nodes - CORRECT ANSWERS-b. Shortness of breath and
fatigue
During the second trimester of fetal development, the primary site of blood cell production is:
a. Bone marrow
b. Spleen
c. Lymph nodes
d. Liver - CORRECT ANSWERS-d. Liver
Extravascular hemolysis can occur when:
a. RBCs are mechanically ruptured
b. RBCs extravasate for the blood vessels into the tissues
c. Splenic macrophages ingest senescent cells
d. Erythrocytes are trapped in blood clots outside the blood vessels - CORRECT ANSWERS-c.
Splenic macrophages ingest senescent cells
, For a patient with classic iron study values that are equivocal for iron deficiency, which of the
following tests would be most helpful in determining whether iron deficiency is present or not?
a. Zinc protoporphyrin
b. Peripheral blood sideroblast assessment
c. Soluble transferrin receptor
d. Mean cell hemoglobin - CORRECT ANSWERS-c. Soluble transferrin receptor
Hematopoietic stem cells produce all lineages of blood cells in sufficient quantities over the
lifetime of an individual because they:
a. Are unipotent
b. Have the ability of self-renewal by asymmetric division
c. Are present in large numbers in the bone marrow niches
d. Have a low mitotic potential in response to growth factors - CORRECT ANSWERS-b. Have
the ability of self-renewal by asymmetric division
How frequently should fire alarms and sprinkler systems be tested?
a. Weekly
b. Monthly
c. Quarterly
d. Annually - CORRECT ANSWERS-c. Quarterly
Hypoxia stimulates RBC production by:
a. Inducing more pluripotent stem cells into erythroid lineage
b. Stimulating EPO production by the kidney
c. Increasing the number of RBC mitoses
d. Stimulating the production of fibronectin by macrophages of the bone marrow - CORRECT
ANSWERS-b. Stimulating EPO production by the kidney
In general, the hereditary hemochromatoses result from mutations that impair:
a. The manner in which developing red cells acquire and manage iron
b. The hepcidin-ferroportin iron regulatory system
correct answers
A hemoglobin molecule is composed of:
a. One heme molecule and four globin chains
b. Ferrous iron, protoporphyrin IX, and a globin chain
c. Protoporphyrin IX and four globin chains
d. Four heme molecules and four globin chains - CORRECT ANSWERS-d. Four heme
molecules and four globin chains
A patient has a hemoglobin level of 8.0 g/dL. According to the rule of three, what is the expected
range for the hematocrit?
a. 21% to 24%
b. 23.7% to 24.3%
c. 24% to 27%
d. 21% to 27% - CORRECT ANSWERS-d. 21% to 27%
All of the following cells are normally seen in CSF, serous fluids, and synovial fluids except:
a. Lining cells
b. Neutrophils
c. Lymphocytes
d. Monocytes/histiocytes (macrophages) - CORRECT ANSWERS-b. Neutrophils
An increase in which one of the following suggests a shortened life span of RBCs and hemolytic
anemia?
,a. Hemoglobin
b. Hematocrit
c. Reticulocyte count
d. Red cell distribution width - CORRECT ANSWERS-`c. Reticulocyte count
Basophils and mast cells have high-affinity surface receptors for which immunoglobulin?
a. A
b. D
c. E
d. G - CORRECT ANSWERS-c. E
Common clinical symptoms of anemia include:
a. Splenomegaly
b. Shortness of breath and fatigue
c. Chills and fever
d. Jaundice and enlarged lymph nodes - CORRECT ANSWERS-b. Shortness of breath and
fatigue
During the second trimester of fetal development, the primary site of blood cell production is:
a. Bone marrow
b. Spleen
c. Lymph nodes
d. Liver - CORRECT ANSWERS-d. Liver
Extravascular hemolysis can occur when:
a. RBCs are mechanically ruptured
b. RBCs extravasate for the blood vessels into the tissues
c. Splenic macrophages ingest senescent cells
d. Erythrocytes are trapped in blood clots outside the blood vessels - CORRECT ANSWERS-c.
Splenic macrophages ingest senescent cells
, For a patient with classic iron study values that are equivocal for iron deficiency, which of the
following tests would be most helpful in determining whether iron deficiency is present or not?
a. Zinc protoporphyrin
b. Peripheral blood sideroblast assessment
c. Soluble transferrin receptor
d. Mean cell hemoglobin - CORRECT ANSWERS-c. Soluble transferrin receptor
Hematopoietic stem cells produce all lineages of blood cells in sufficient quantities over the
lifetime of an individual because they:
a. Are unipotent
b. Have the ability of self-renewal by asymmetric division
c. Are present in large numbers in the bone marrow niches
d. Have a low mitotic potential in response to growth factors - CORRECT ANSWERS-b. Have
the ability of self-renewal by asymmetric division
How frequently should fire alarms and sprinkler systems be tested?
a. Weekly
b. Monthly
c. Quarterly
d. Annually - CORRECT ANSWERS-c. Quarterly
Hypoxia stimulates RBC production by:
a. Inducing more pluripotent stem cells into erythroid lineage
b. Stimulating EPO production by the kidney
c. Increasing the number of RBC mitoses
d. Stimulating the production of fibronectin by macrophages of the bone marrow - CORRECT
ANSWERS-b. Stimulating EPO production by the kidney
In general, the hereditary hemochromatoses result from mutations that impair:
a. The manner in which developing red cells acquire and manage iron
b. The hepcidin-ferroportin iron regulatory system
