NUR 521 Pharmacology/Medication Administration
Mount Saint Joseph University
NUR 521 Exam 3 LATEST 2024-2025 ACCURATE
FALL- SPRING TERM Pharmacology/Medication
Administration
What type of drug is Glipizide and Glyburide?
Sulfonylureas/anti-diabetic agent
How do Glipizide and Glyburide act?
Lowers blood sugar by stimulating the release of insulin from the pancreas and increasing
sensitivity to insulin at the receptor sites.
What are some AEs of Glipizide and Glyburide?
Hypoglycemia, anorexia, nausea, vomiting, heartburn, metallic taste
How long does Glipizide or Glyburide take to onset?
2 hours
What are some interactions for Glipizide and Glyburide?
Alcohol, NSAIDS, beta blockers
,NUR 521 Pharmacology/Medication Administration
Mount Saint Joseph University
What allergies to you assess for with Glipizide and Glyburide?
Sulfonamide allergies
How should Glipizide and Glyburide be given?
Give before 1st meal, may need a second dose before dinner
What needs to be monitored with Glipizide and Glyburide?
Monitor glucose levels, HbA1c levels, CBC, liver, renal
What type of drug is Repaglinide?
Meglitinide; anti-diabetic agent
How does Repaglinide act?
Stimulated release of insulin from pancreatic beta cells but more rapidly than
Glipizide/Glyburide; secretagogue
What are some AEs of Repaglinide?
Hypoglycemia, hyperglycemia
,NUR 521 Pharmacology/Medication Administration
Mount Saint Joseph University
When should Repaglinide be taken?
30 minutes before mean
What type of drug is Metformin?
Biguanide; anti-diabetic agent
How does Metformin act?
Decreases hepatic glucose production; decreases intestinal glucose absorption; increases
sensitivity of the cell receptor to insulin
What are contraindications of Metformin?
Hepatic disease, renal disease, heart failure
What are some AEs of Metformin?
Anorexia/weight loss, nausea/vomiting, abdominal discomfort, dyspepsia, flatulence, diarrhea
Is there a risk for hypoglycemia with Metformin?
, NUR 521 Pharmacology/Medication Administration
Mount Saint Joseph University
There is a low risk because of the indirect actions
What are some drug interactions with Metformin?
No alcohol
What needs to be monitored with Metformin?
Symptoms of lactic acidosis - should be reported; glucose levels; HbA1c
What type of drug is Pioglitazone?
Thiazolidinediones (glitazones); anti-diabetic agent
How does Pioglitazone act?
Improves insulin sensitivity in muscle and adipose
What are some AEs of Pioglitazone?
HF, angioedema, hypoglycemia, hepatic toxicity
Mount Saint Joseph University
NUR 521 Exam 3 LATEST 2024-2025 ACCURATE
FALL- SPRING TERM Pharmacology/Medication
Administration
What type of drug is Glipizide and Glyburide?
Sulfonylureas/anti-diabetic agent
How do Glipizide and Glyburide act?
Lowers blood sugar by stimulating the release of insulin from the pancreas and increasing
sensitivity to insulin at the receptor sites.
What are some AEs of Glipizide and Glyburide?
Hypoglycemia, anorexia, nausea, vomiting, heartburn, metallic taste
How long does Glipizide or Glyburide take to onset?
2 hours
What are some interactions for Glipizide and Glyburide?
Alcohol, NSAIDS, beta blockers
,NUR 521 Pharmacology/Medication Administration
Mount Saint Joseph University
What allergies to you assess for with Glipizide and Glyburide?
Sulfonamide allergies
How should Glipizide and Glyburide be given?
Give before 1st meal, may need a second dose before dinner
What needs to be monitored with Glipizide and Glyburide?
Monitor glucose levels, HbA1c levels, CBC, liver, renal
What type of drug is Repaglinide?
Meglitinide; anti-diabetic agent
How does Repaglinide act?
Stimulated release of insulin from pancreatic beta cells but more rapidly than
Glipizide/Glyburide; secretagogue
What are some AEs of Repaglinide?
Hypoglycemia, hyperglycemia
,NUR 521 Pharmacology/Medication Administration
Mount Saint Joseph University
When should Repaglinide be taken?
30 minutes before mean
What type of drug is Metformin?
Biguanide; anti-diabetic agent
How does Metformin act?
Decreases hepatic glucose production; decreases intestinal glucose absorption; increases
sensitivity of the cell receptor to insulin
What are contraindications of Metformin?
Hepatic disease, renal disease, heart failure
What are some AEs of Metformin?
Anorexia/weight loss, nausea/vomiting, abdominal discomfort, dyspepsia, flatulence, diarrhea
Is there a risk for hypoglycemia with Metformin?
, NUR 521 Pharmacology/Medication Administration
Mount Saint Joseph University
There is a low risk because of the indirect actions
What are some drug interactions with Metformin?
No alcohol
What needs to be monitored with Metformin?
Symptoms of lactic acidosis - should be reported; glucose levels; HbA1c
What type of drug is Pioglitazone?
Thiazolidinediones (glitazones); anti-diabetic agent
How does Pioglitazone act?
Improves insulin sensitivity in muscle and adipose
What are some AEs of Pioglitazone?
HF, angioedema, hypoglycemia, hepatic toxicity
