CNS PNS
Spinal Motor Sensory
Brain
Cord Neurons Neurons
Autonomic Somatic
Nervous System Nervous System
Sympathetic Parasympathetic
Nervous System Nervous System
(Adrenergic) (Cholinergic)
“Fight or Flight” “Rest and Digest”
Primarily Norepinephrine (Adrenaline) Primarily ACh
Alpha Receptors: vessels Muscarinic Receptors
Beta1-Receptors: heart Nicotinic Receptors
Beta2-Receptors: bronchial/vascular
smooth muscle
Dopaminergic: renal/mesenteric artery
MED CLASSES/EXAMPLE MEDS
ADRENERGIC AGONIST (SYMPATHOMIMETIC): CHOLINERGIC AGONISTS
Mimics the effects of the SNS. (dobutamine, (PARASYMPATHOMIMETIC): Mimic the effects
dopamine, epinephrine, norepinephrine, of the PNS. (donepezil, bethanechol,
phenylephrine, albuterol, isoproterenol, pyridostigmine).
salmeterol).
ADRENERGIC BLOCKING AGENTS ANTICHOLINERGIC AGENTS
(SYMPATHOLYTIC): Block the effects of the SNS. (PARASYMPATHOLYTIC): Block the effects
(beta-blockers, amiodarone, tamsulosin, doxazosin, of the PNS. (atropine, scopolamin, ipratropium,
phentolamine). trospium).
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