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Exam (elaborations)

CNPR Exam Questions and Answers Graded A 2024

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1. How are drugs sorted into therapeutic groups and classes? - first by the conditions that they are used to treat. and then by their mechanisms of action 2. Bone marrow transplants. - are a type of stem cell therapy. unless patient's own cells are reinjected. 3. What does AMA stand for? - American Medical Association 4. What section of a drug's package insert describes situations in which the drug should not be used because the risks outweigh the therapeutic benefits? - contraindications 5 What is tertiary care? - highly specialized medical and surgical care provided by a large medical center for unusual or complex medical problems 6. Which of the following is NOT one of the stages in the classic approach to brand development strategy covered in your manual? - brand quality 7 What are vasodilators used to do? - decrease vascular resistance and increase blood flow 8. What is the name of the condition that occurs after a specific dose of a drug is given at such regular intervals that absorption and elimination (and therefore drug plasma concentration) have become fairly constant? - Steady State 9. Which statement is TRUE about ocular administration? - Ocular administration is used primarily to treat the eye. 10. Which entities invest's the most money in pharmaceutical R&D? - U.S. pharmaceutical companies 11. How are most drugs excreted? - via the kidneys 12. Over the last few decades, what has happened to legal limitations on sales' reps discussions about off label uses? - Limitations have decreased. 14. What does it mean if two drugs are at parity? - Both drugs are essentially in a neutral position. 15 Who is most likely to benefit from electronic sampling programs? - Everyone would benefit equally from electronic sampling programs 16. When referring to medication dosage, which abbreviation means "one-half' - SS 17 What is an internist? - a physician who practices internal medicine 18. Which of the following is a type of white blood cell? - Lymphocytes 19. Why are novice sales representatives often placed in charge of negotiating MCO formularies? - They are not. This job is usually reserved for more experienced reps. 20. What distinguishes pharmacodynamics from pharmacokinetics? - Pharmacodynamics studies the how the body affects drugs. 21 What proportion of the drugs tested on human subjects are eventually approved by the FDA? - about 70% 22. According to a study discussed in your manual, how do most physicians prefer to receive their drug samples? - directly from sales representatives 23. Which of the following is an example of a central value? - I buy Advil to show that I'm a modern consumer. 24. Which of the following specialties likely has the MOST emergency calls? - cardiologist 25. What affects the rate of active transport? - neither the availability of carriers nor the availability of energy 26. Over the last few decades, what has happened to the FDA approval time for new drugs? - It has been shortened to reduce the cost of new drug development. 27. Which of the following would NOT help improve compliance? - pharmacists understanding how generics differ from brand name drugs 28. Which entity chooses a drug's trade name? - the FDA 29. What type of stem cells are obtained from embryos and can develop into any cell type? - totipotent 30. As the price a patient pays for a prescription increases, what happens to the likelihood that the patient will fill it? - It remains unaffected because the prescription is needed 31. Most involuntary movements come from which type of muscle tissue? - cardiac and smooth 32. Which of the following is NOT one of the body's major organ systems? - the cellular system 33. How do most drugs exert their primary physiological effects? - by binding to cell receptors that are sensitive to their presence 34. What is the most reliable source of information for determining therapeutically equivalent drug products? - Orange Book 35. What does subcutaneous mean? - beneath the outer skin 36. What should a sales representative do if all of the prime spaces in a drug cabinet are coccupied? - ask staff for permission to move some of the other products in the cabinet 37. It is inappropriate for physicians' prescribing behaviors to be educated by their personal tastes and idiosyncrasies - TRUE 38. The FDA defines API as the active ingredient in a drug, which produces the desired change in the body. - pharmaceutical 39. What are the 2 legal classifications of wholesalers? - primary and secondary wholesale distributors 40. What term describes the usage of a medication for purposes other than the FDA-approved indications on the labeling? - off-label usage 41. What is the acronym for pharmacokinetics? - PK 42. The dosage range of a drug that is both safe and beneficial is known as the therapeutic window. - True 43. What is typically NOT a characteristic of a pharmaceutical sales rep? - Pharmaceutical sales reps are not concerned about competitors. 44. What entity grants drug patents? - The US Patent and Trademark Office 45. Which of the following refers to all active and inert pharmaceutical ingredients in a drug,including fillers and colors? - formulation 46. What is the difference between potency and efficacy? - potency refers to the drug's strength, while efficacy refers to its effectiveness 47. What is the minimum level of education required for a nurse practitioner? - a graduate degree 48. How many names must a drug have? - at least three 49. How has a longer development time increased the cost of bringing a new drug to market? - Increasing the cost of capital 50. Senior citizens consume over times as many pharmaceuticals as people under 65. - three 51. What agency regulates the distribution and use of narcotics? - DEA 52. What is passive diffusion? - when a substance freely moves through a membrane from a high concentration gradient to a low one 53. What are the MAIN categories of drugs under FDA jurisdiction? - prescription and non prescription 55. What are all metabolites? - products of metabolism 56. When a drug is administered orally, where does first-pass metabolism occur? - liver 57. What is the medical term for swelling? - edema 58. Which of the following is NOT part of the Seven Step Cascade of Emotion? - be a consultant, not a rep 59. Which part of a clinical research paper is frequently referred to as the road map? - abstract 60. Which of the following is a main active ingredient in lung surfactants? - theophylline 61. What does parenteral mean? - injection 62. Which term denotes a type of substance that enhances the action of a drug or antigen? - adjunvant 63. If a sales representative's product is placed on the second tier of a standard three-tier formulary, which of the following is most likely true? - It probably has exclusive preferred status if it is not at parity with any other drugs 64. Which of the following is NOT one of the four basic transport mechanisms? - homeostasis 65. Which statement accurately describes a relationship between drug agonists and antagonists? - Agonists and antagonists can be used together. 66. What is the study of the effects and movement of drugs in the human body? - clinical pharmacology 67. According to your manual, what is a common complaint that physicians have about traditional sampling methods? - that drug sample supply is too unpredictable 68. Which of these entities is formed by two or more hospitals or other healthcare entities to negotiate reduced rates with its aggregated purchasing power? - GPO 69. What is another name for a drug derived from a biologic compound? - large molecule 70. What is the most common policy regarding pharmaceutical reps dispensing drug samples in hospitals? - drug sampling is often forbidden 71 Which of the following would help you build trust with a physician? - asking if he or she is having any problems with the managed care coverage of your products 72. What term denotes the difference between the usual effective dose and the dose that induces severe or life-threatening side effects? - margin of safety 73. What are excipients? - the inert ingredients in a drug formulation 74. What is another term for the AWP? - list price 75. Which of these is the most likely use for a uterotonic agent? - to induce labor 76. As of November 2013, which of these countries has legalized DTC advertising of prescription drugs? - none of these 77. Why are oral drugs often taken on an empty stomach? - to pass through the stomach more quickly 78. What is one factor that differentiates community health centers from hospitals? - community health center formularies are more restrictive 79. How does drug sampling provide a social benefit? - doctors often use drug samples to treat patients who otherwise could not afford it 80. Which medical term denotes the use of a stethoscope to listen to the heart? - ausculation 81. What do enteric coatings do? - prevents dissolution in the stomach 82. What is the duration of exclusivity for orphan drugs? - 7 years 83. What do National Account Managers do? - negotiate contracts with MCO and PBM 84. What does it usually mean if a drug recall is voluntary? - The manufacturer has recalled the product on its own. but negotiated with the FDA beforehand. 85. Which phase of clinical trials is also known as the pivotal phase? - Phase III 86. During which phase of clinical trials is the new drug's safety and effectiveness first tested in the target group? - Phase II 87. How do antacids work? - by raising gastric PH 88. What is one of the biggest time wasters for a pharmaceutical sales rep? - Travel Time 89. What happens when equilibrium is reached? - equal numbers of molecules cross the membrane in both directions 90. What are the most common vectors used in gene therapy? - viruses 91. What is the percentage fee that the dispenser pays the wholesaler for distribution? - upcharge 92. What is the difference between a chronic (or continuing) reaction, and a delayed reaction? - chronic reactions persist for a long time, delayed reactions take some time to develop 93 What is clinical effect? - the response produced by a medication 94. Which of the following is an example of noncompliance? - a patient forgetting to take a drug at a specified time of day 95. What is the average circulation time of blood? - about a minute 96. What is one way in which pharmaceutical selling is different from selling in most other industries? - representative do NOT sell to the end user of the product 97. From what types of entities do primary wholesale distributors buy most of their drugs? - manufacturers 98. What is the Office of the Inspector General (01G)? - an arm of the Dept of Health and Human Services 99. What are doctors required to consider when deciding whether or not to prescribe a particular drug? - the severity of the disorder being treated and the effect it has on the patients quality of life

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