UAMS IMMUNOLOGY EXAM |
GUARANTEED PASS |SOLVED!!
Syphilis, caused by Treponema pallidum. Spirochetes - ACCURATE
ANSWERS✔✔ What is the ulcerative disease that facilitates the
transmission of HIV and what organism is it caused by? What is the term
for its shape?
Usually sexual and congenital via the placenta. - ACCURATE
ANSWERS✔✔ What is the transmission for Syphilis?
Appearance of chancre, which is a painless superficial ulcer at the
inoculation site that heals spontaneously. Serum reactive within 1-3
weeks after chancre appears. Spirochetes in chancre is infectious. -
ACCURATE ANSWERS✔✔ What is the physical indication of primary
syphilis? What is the infectious stage?
Rash and fever with spontaneous healing after several weeks, serology is
almost always positive. Appears 6-8 weeks after appearance of chancre.
Spirochetes in rash is infectious. - ACCURATE ANSWERS✔✔ What
characterizes the secondary stage of syphilis and when does this usually
appear? What is the infectious stage?
Usually no clinical manifestations and may last for up to 30 years,
serology is positive. Mother can pass to baby during this stage in vertical
transmission. - ACCURATE ANSWERS✔✔ What characterizes the
latent stage of syphilis?
,Intrauterine infection of the fetus, likelihood of infection increases as
pregnancy progresses, rhinitis and rash present as clinical symptoms.
The Hutchinson's triad appears - notches in teeth, eye damage (keratitis),
and deafness. - ACCURATE ANSWERS✔✔ What characterizes
congenital syphilis?
Gumma lesions that can affect any site but are most common in
cardiovascular and CNS sites. - ACCURATE ANSWERS✔✔ What
characterizes the tertiary syphilis stage?
Darkfield microscopy is used to look for corkscrew shaped microbes
with flexing motility. Isolation methods are not used. - ACCURATE
ANSWERS✔✔ What is the fastest method of detection for syphilis?
What is the slide examined for? What method is not used?
Detection of AGNs. Direct - Monoclonal ABY and material from lesion.
Indirect - patient specimen and ABY/Ig and ABY/TP - ACCURATE
ANSWERS✔✔ What is fluorescent testing most commonly used for?
What does direct fluorescent use? What does indirect fluorescent use?
Diagnostic tool. - ACCURATE ANSWERS✔✔ What is syphilis
serology used for?
Sensitivity - ACCURATE ANSWERS✔✔ What indicates the frequency
of positive test results in patient WITH a particular disease; detects true
positives
, Specificity - ACCURATE ANSWERS✔✔ What indicates the frequency
of negative test results in patients WITHOUT a disease; detects true
negatives
Screening - non treponemal test use patient ABYs with reagin to
cardiolipin, don't test organism directly. Less expensive and easily
performed. Usually only helpful with sensitivity - can get many false
positives.
Confirmatory - treponemal test that tests organism directly; expensive
and harder to perform. Helpful with sensitivity and specificity - will help
ID true positives. - ACCURATE ANSWERS✔✔ What is the difference
between screening lab tests and confirmatory lab tests?
Patient ABY with reagin to cardiolipin as reagent. Flocculation is used
which is a special precipitation test that sediments out the AGN in very
fine particles. - ACCURATE ANSWERS✔✔ How is non treponemal
screening test performed?
Results are pos within 1-4 weeks after chancre appearance. Not all
patients show pos in early primary and late stages. Peak titer occurs
during the secondary or early latent stages. - ACCURATE
ANSWERS✔✔ How are the results determined in a non treponemal
screening test? When does the peak titer occur?
The prozone - ACCURATE ANSWERS✔✔ What are false negatives
due to in secondary syphilis stages?
GUARANTEED PASS |SOLVED!!
Syphilis, caused by Treponema pallidum. Spirochetes - ACCURATE
ANSWERS✔✔ What is the ulcerative disease that facilitates the
transmission of HIV and what organism is it caused by? What is the term
for its shape?
Usually sexual and congenital via the placenta. - ACCURATE
ANSWERS✔✔ What is the transmission for Syphilis?
Appearance of chancre, which is a painless superficial ulcer at the
inoculation site that heals spontaneously. Serum reactive within 1-3
weeks after chancre appears. Spirochetes in chancre is infectious. -
ACCURATE ANSWERS✔✔ What is the physical indication of primary
syphilis? What is the infectious stage?
Rash and fever with spontaneous healing after several weeks, serology is
almost always positive. Appears 6-8 weeks after appearance of chancre.
Spirochetes in rash is infectious. - ACCURATE ANSWERS✔✔ What
characterizes the secondary stage of syphilis and when does this usually
appear? What is the infectious stage?
Usually no clinical manifestations and may last for up to 30 years,
serology is positive. Mother can pass to baby during this stage in vertical
transmission. - ACCURATE ANSWERS✔✔ What characterizes the
latent stage of syphilis?
,Intrauterine infection of the fetus, likelihood of infection increases as
pregnancy progresses, rhinitis and rash present as clinical symptoms.
The Hutchinson's triad appears - notches in teeth, eye damage (keratitis),
and deafness. - ACCURATE ANSWERS✔✔ What characterizes
congenital syphilis?
Gumma lesions that can affect any site but are most common in
cardiovascular and CNS sites. - ACCURATE ANSWERS✔✔ What
characterizes the tertiary syphilis stage?
Darkfield microscopy is used to look for corkscrew shaped microbes
with flexing motility. Isolation methods are not used. - ACCURATE
ANSWERS✔✔ What is the fastest method of detection for syphilis?
What is the slide examined for? What method is not used?
Detection of AGNs. Direct - Monoclonal ABY and material from lesion.
Indirect - patient specimen and ABY/Ig and ABY/TP - ACCURATE
ANSWERS✔✔ What is fluorescent testing most commonly used for?
What does direct fluorescent use? What does indirect fluorescent use?
Diagnostic tool. - ACCURATE ANSWERS✔✔ What is syphilis
serology used for?
Sensitivity - ACCURATE ANSWERS✔✔ What indicates the frequency
of positive test results in patient WITH a particular disease; detects true
positives
, Specificity - ACCURATE ANSWERS✔✔ What indicates the frequency
of negative test results in patients WITHOUT a disease; detects true
negatives
Screening - non treponemal test use patient ABYs with reagin to
cardiolipin, don't test organism directly. Less expensive and easily
performed. Usually only helpful with sensitivity - can get many false
positives.
Confirmatory - treponemal test that tests organism directly; expensive
and harder to perform. Helpful with sensitivity and specificity - will help
ID true positives. - ACCURATE ANSWERS✔✔ What is the difference
between screening lab tests and confirmatory lab tests?
Patient ABY with reagin to cardiolipin as reagent. Flocculation is used
which is a special precipitation test that sediments out the AGN in very
fine particles. - ACCURATE ANSWERS✔✔ How is non treponemal
screening test performed?
Results are pos within 1-4 weeks after chancre appearance. Not all
patients show pos in early primary and late stages. Peak titer occurs
during the secondary or early latent stages. - ACCURATE
ANSWERS✔✔ How are the results determined in a non treponemal
screening test? When does the peak titer occur?
The prozone - ACCURATE ANSWERS✔✔ What are false negatives
due to in secondary syphilis stages?
