AM #4
For this assignment, I have chosen a family member who was diagnosed with infectious
Mononucleosis. Mononucleosis, popularly known as kissing virus or simply mono, is a highly
contagious and infectious disease. It is a disease that can be transferred by kissing, but it may
also be spread through other mouth-swapping behaviors like exchanging utensils or beverages.
In other words, mono is spread mostly by saliva, especially the spit that comes out when you
cough. Athough, the most frequent way for these viruses to transmit is through body fluids, like
saliva, these viruses can also transmit through blood and semen, during sexual intercourse,
blood transfusions, and organ transplants.
The Epstein-Barr virus (EBV) is the causative agent for infectious mononucleosis. On
the other hand, the cytomegalovirus (CMV) causes a milder form of mononucleosis than
Epstein-Barr virus infectious mononucleosis. In teenagers and young adults, the Epstein-Barr
virus can cause infectious mononucleosis. Many people are infected with the Epstein-Barr virus
while they are young. In most cases, EBV infections in children do not generate symptoms, or if
they do, the symptoms are difficult to identify from those of other minor, transient childhood
diseases. Even when the symptoms of infectious mononucleosis have faded, the Epstein-Barr
virus will stay latent in the pharynx and blood cells of that individual for the rest of his or her
life. However, the virus can reactivate on a regular basis, generally without causing symptoms.
If the Epstein-Barr virus reactivates, those with compromised immune systems are more prone
to develop symptoms.
In more detail, The Epstein-Barr virus (EBV) infects people throughout the rest of their
lives. Latently infected B cells transit the germinal center (GC) to become resting memory cells,
per the germinal center model (GCM). The virus remains dormant here, periodically
reactivating to infect new B cells and complete the infection cycle.
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