GUIDE
1. What is Pharmacology: the study of drugs and their
interactions with living systems
2. 3 different drug names: Generic, Trade, and Chemical
3. Pharmacokinetic phase: Activities within body after drug is
administered. Ab- sorption, distribution, metabolism, excretion, and
half life
4. Pharmacodynamic phase: what the drug does to the body
5. Half life: time required for the body to eliminate 50% of a drug-
short life= more frequent doses
Longer half life= less frequent doses
CAUTION WITH PTS WITH LIVER AND OR KIDNEY DISEASE- Takes linger to
get
rid of drugs
6. Pharmaceutic Phase: Dissolution of the drug
7. Drug action: Enters systemic
circulation Exposes body tissue to
effects of drug
Certain drugs may have affinity for certain organs
or tissues Greatest action at cellular level on these
sites (target sites)
8. Agonist: Drugs that bind with receptor to produce a therapeutic
response
1/7
, NU 150 EXAM 1 GALEN COLLEGE STUDY
9. Antagonist: Blocks drug; Join with receptors to prevent action of
GUIDE
agonist; Narcan blocks effects of morphine overdose
10.Adverse drug reactions: undesirable drug effects
11.Anaphylactic shock: Severe allergic reaction- requires immediate
medical at- tention- nurse- check in pts allergies especially when giving
antibiotics, narcotics, and blood products
12.Signs and symptoms of Anaphylactic shock: QUICK
ONSET mild itching rash
burning skin
vascular
dilation
generalized edema especially around face
and lips pallor/cyanosis
dizziness/fainting
sneezing/tightness in
chest/cough WHEEZING
Tachycardia
13.Angioedema: Collections of fluid in the Sub Q tissues
14.Drug Idiosyncrasy: any unusual or abnormal response that differs
from the response normally expected to a specific drug and dosage-
Example= sleeping pills make you stay awake
15.Cumulative Effect: condition that occurs when the body cannot
metabolize a drug before additional doses are administered
2/7