BMTCN Foundations of Transplant
Commonly recognized marker of hematopoietic stem cells, used to separate them from other
populations of leukocytes - Answer -CD34
This type of bone marrow consists of fat cells and resides in the hollow interior of the middle portion of
long bones. - Answer -Yellow
Bone marrow ______________ cells contribute to hematopoiesis by indirectly facilitating the movement
of hematopoietic stem cells out of the bone marrow microenvironment and into peripheral circulation. -
Answer -Stromal
Name the three types of granulocytes - Answer -Neutrophils, basophils and eosinophils
Stromal cells express a chemokine known as _________. - Answer -SDF-1a
_________ are small proteins produced by nonhematopoietic cells that help guide migration of cells that
are attached to them by following the signals of increasing concentration towards their source. - Answer
-Chemokines
________ are intracellular signaling proteins that act by binding to a receptor on a target cell. There are
three main classes: lymphokines, monokines and growth factors. - Answer -Cytokines
What are the three main classes of cytokines? - Answer -Lymphokines, monokines and growth factors.
Commonly recognized marker of hematopoietic stem cells, used to separate them from other
populations of leukocytes - Answer -CD34
This type of bone marrow consists of fat cells and resides in the hollow interior of the middle portion of
long bones. - Answer -Yellow
Bone marrow ______________ cells contribute to hematopoiesis by indirectly facilitating the movement
of hematopoietic stem cells out of the bone marrow microenvironment and into peripheral circulation. -
Answer -Stromal
Name the three types of granulocytes - Answer -Neutrophils, basophils and eosinophils
Stromal cells express a chemokine known as _________. - Answer -SDF-1a
_________ are small proteins produced by nonhematopoietic cells that help guide migration of cells that
are attached to them by following the signals of increasing concentration towards their source. - Answer
-Chemokines
________ are intracellular signaling proteins that act by binding to a receptor on a target cell. There are
three main classes: lymphokines, monokines and growth factors. - Answer -Cytokines
What are the three main classes of cytokines? - Answer -Lymphokines, monokines and growth factors.
