chemo study guide 100% Updated!!
T/F: chemotherapy consenting is to be performed by the pt's attending physician - ANSWERTRUE
what is required if chemo is being used in a new way and or a new drug is added to the regimen -
ANSWERNEW CONSENT
T/F - a patient can leave their shoes on when height and weight are obtained only if the pt is
suffering from peripheral neuropathy - ANSWERFALSE
who determines if actual, ideal, or adjusted body weight is to be used in chemo dosing -
ANSWERphysician
the calvert formula is used to calculate the dose of what drug - ANSWERcarboplatin
What does AUC measure - ANSWERarea under the curve/drug exposure
T/F - Mrs. S is receiving carboplatin dosed with an AUC of 6 and Mrs. H is receiving carboplatin with
AUC of 2. the nurse knows Mrs. S may have more toxicity to the drug since her AUC is higher than
Mrs. H - ANSWERTRUE
when can the UPMC fellow write orders independently - ANSWERafter first three months. A UPMC
Fellow cannon write orders independently in the first three months
T/F - the nurse should avoid bruised sites, the use of hand/AC veins, and sites distal to veins that
have experienced venipuncture in the past 24 hrs when assessing where to place a new IV site for
chemo admin - ANSWERTRUE
rate of vesicant IV push chemo and when to assess BR - ANSWERvesicant chemo administered IV
push should be admin at a rate of 5 ml/minute and BR assessed after ever 2-3 mL of drug
administered
T/F - the most accurate method to measure Cr Cl is to collect urine for 24 hrs to measure level -
ANSWERTRUE
T/F - when administering IV push medication the nurse should open the clamp of compatible IV
solution until increased flow is seen to dilute the agent during administration - ANSWERTRUE
during 2 RN check of chemo, what is verified and where - ANSWERcorrect patient and dose is to be
verified at the bedside
what has to run through a central line - ANSWERcontinuous infusion of vesicants must be through a
central line
who should be taught about excretion safety precautions - ANSWERfamily and friends
how long do excretion precautions last - ANSWER3 to 7 days
T/F - when evaluating a patient prior to chemo, the nurse notes the patient recently had weight loss.
the nurse recalculates the dose and discovers a change in the dose greater than 10%. the next step
for the nurse is to notify the attending physician that the patient will need re consented because of
dose adjustment - ANSWERFALSE
, how do alkylating agents work - ANSWERthey are cell cycle non specific. they work on dividing and
resting cells
when are alkylating agents effective - ANSWERalkylating agents are effective in slow growing tumors
and large tumors that have few actively dividing cells
three common toxicities in alkylating agents - ANSWERN/V, myelosuppression, infertility,
hypersensitivity, alopecia, TLS
what class of drugs can cross the blood brain barrier, increasing a patient's risk for CNS Toxicities? -
ANSWERnitrosureas
what is the solvent for carmustine (BCNU) - ANSWERsterile alcohol
what formula is used to calculate the carboplatin dosage - ANSWERcalvert formula
T/F - temozolamid (temodar) effectively crosses the blood brain barrier - ANSWERTrue
what drugs do patients feel intoxicated during - ANSWERcarmusting (BCNU)
busulfan prophylaxis - ANSWERpatients are prophylactically medicated with anticonvulsants before
receiving busulfan and for 24 hrs after the last dose to prevent seizures
T/F - Oxaliplatin should only be mixed with D5W - ANSWERTRUE
which drug should always be given with MESNA= - ANSWERifosfamide
late complication of pts who receive busulfan - ANSWERpulmonary fibrosis
what do the platinum alkylating agents include - ANSWERcisplatin, carboplatin, and oxaliplatin
what kind of drug is cisplatin - ANSWERHIGHLY emetogenic drug
Pretreatment hydration is administered to prevent this toxicity of cisplatin: _________ -
ANSWERnephrotoxicity
T/F: Cisplatin (platinol) should be administered before paclitaxel (taxol) to prevent delayed paclitaxel
excretion and increased toxicity - ANSWERFALSE - should be administered before
T/F - electrolyte levels need to be closely monitored and often supplemented for cisplatin (platinol) -
ANSWERTRUE
what increases risk for reaction with carboplatin - ANSWERthe more treatments a patient receives
increases the risk for reaction with carboplatin (paraplatin)
what is a dose limiting adverse event associated with oxaliplatin (eloxatin) - ANSWERneurotoxicity
patient consideration with oxaliplatin - ANSWERpatients should avoid cold fluids for 5 days after
receiving oxaliplatin to help prevent acute neurotoxicity
list two common side effects of antimetabolites - ANSWERmyelosuppression, mucositis, GI
symptoms, liver dysfunction
T/F - HD of MTX should not be administered to patients with abnormal renal function - ANSWERTRUE
leucovorin rescue begins when - ANSWERbegins 24 hours after the end of MTX infusion
T/F: chemotherapy consenting is to be performed by the pt's attending physician - ANSWERTRUE
what is required if chemo is being used in a new way and or a new drug is added to the regimen -
ANSWERNEW CONSENT
T/F - a patient can leave their shoes on when height and weight are obtained only if the pt is
suffering from peripheral neuropathy - ANSWERFALSE
who determines if actual, ideal, or adjusted body weight is to be used in chemo dosing -
ANSWERphysician
the calvert formula is used to calculate the dose of what drug - ANSWERcarboplatin
What does AUC measure - ANSWERarea under the curve/drug exposure
T/F - Mrs. S is receiving carboplatin dosed with an AUC of 6 and Mrs. H is receiving carboplatin with
AUC of 2. the nurse knows Mrs. S may have more toxicity to the drug since her AUC is higher than
Mrs. H - ANSWERTRUE
when can the UPMC fellow write orders independently - ANSWERafter first three months. A UPMC
Fellow cannon write orders independently in the first three months
T/F - the nurse should avoid bruised sites, the use of hand/AC veins, and sites distal to veins that
have experienced venipuncture in the past 24 hrs when assessing where to place a new IV site for
chemo admin - ANSWERTRUE
rate of vesicant IV push chemo and when to assess BR - ANSWERvesicant chemo administered IV
push should be admin at a rate of 5 ml/minute and BR assessed after ever 2-3 mL of drug
administered
T/F - the most accurate method to measure Cr Cl is to collect urine for 24 hrs to measure level -
ANSWERTRUE
T/F - when administering IV push medication the nurse should open the clamp of compatible IV
solution until increased flow is seen to dilute the agent during administration - ANSWERTRUE
during 2 RN check of chemo, what is verified and where - ANSWERcorrect patient and dose is to be
verified at the bedside
what has to run through a central line - ANSWERcontinuous infusion of vesicants must be through a
central line
who should be taught about excretion safety precautions - ANSWERfamily and friends
how long do excretion precautions last - ANSWER3 to 7 days
T/F - when evaluating a patient prior to chemo, the nurse notes the patient recently had weight loss.
the nurse recalculates the dose and discovers a change in the dose greater than 10%. the next step
for the nurse is to notify the attending physician that the patient will need re consented because of
dose adjustment - ANSWERFALSE
, how do alkylating agents work - ANSWERthey are cell cycle non specific. they work on dividing and
resting cells
when are alkylating agents effective - ANSWERalkylating agents are effective in slow growing tumors
and large tumors that have few actively dividing cells
three common toxicities in alkylating agents - ANSWERN/V, myelosuppression, infertility,
hypersensitivity, alopecia, TLS
what class of drugs can cross the blood brain barrier, increasing a patient's risk for CNS Toxicities? -
ANSWERnitrosureas
what is the solvent for carmustine (BCNU) - ANSWERsterile alcohol
what formula is used to calculate the carboplatin dosage - ANSWERcalvert formula
T/F - temozolamid (temodar) effectively crosses the blood brain barrier - ANSWERTrue
what drugs do patients feel intoxicated during - ANSWERcarmusting (BCNU)
busulfan prophylaxis - ANSWERpatients are prophylactically medicated with anticonvulsants before
receiving busulfan and for 24 hrs after the last dose to prevent seizures
T/F - Oxaliplatin should only be mixed with D5W - ANSWERTRUE
which drug should always be given with MESNA= - ANSWERifosfamide
late complication of pts who receive busulfan - ANSWERpulmonary fibrosis
what do the platinum alkylating agents include - ANSWERcisplatin, carboplatin, and oxaliplatin
what kind of drug is cisplatin - ANSWERHIGHLY emetogenic drug
Pretreatment hydration is administered to prevent this toxicity of cisplatin: _________ -
ANSWERnephrotoxicity
T/F: Cisplatin (platinol) should be administered before paclitaxel (taxol) to prevent delayed paclitaxel
excretion and increased toxicity - ANSWERFALSE - should be administered before
T/F - electrolyte levels need to be closely monitored and often supplemented for cisplatin (platinol) -
ANSWERTRUE
what increases risk for reaction with carboplatin - ANSWERthe more treatments a patient receives
increases the risk for reaction with carboplatin (paraplatin)
what is a dose limiting adverse event associated with oxaliplatin (eloxatin) - ANSWERneurotoxicity
patient consideration with oxaliplatin - ANSWERpatients should avoid cold fluids for 5 days after
receiving oxaliplatin to help prevent acute neurotoxicity
list two common side effects of antimetabolites - ANSWERmyelosuppression, mucositis, GI
symptoms, liver dysfunction
T/F - HD of MTX should not be administered to patients with abnormal renal function - ANSWERTRUE
leucovorin rescue begins when - ANSWERbegins 24 hours after the end of MTX infusion
