Exam Bank Solution Manual for Blood Banking Chapter 7 Graded A+

Exam Bank Solution Manual for Blood Banking Chapter 7 Graded A+ Antibodies to Kidd, Kell, and Duffy blood group antigens share all the following characteristics except: - Answers Enhanced with enzyme treatment Which of the following phenotypes is heterozygous - Answers Fy(a+b+) Why have Lewis system antibodies not been implicated in hemolytic disease of the fetus and newborn - Answers All of the above ( The antigens are not fully developed at birth , Lewis system antibodies do not cross the placenta The antibodies are not clinically significant What phenoytype will be expressed when the Le, Se, and H genes are inherited - Answers Le(a-b+) Which condition is often associated with the presence of anti-I - Answers Mycoplasma pneumonia's infection Red cells that phenotype as S-s are also - Answers U- negative Select the statement that is FALSE regarding anti-P1 - Answers Anti-P1 will not react with enzyme-treated P1 red cells The major histocompatibility complex is located on chromosome 6 and is important in all the following immune functions except - Answers Hemolysis Antigens Yta and Ytb are in this system - Answers Cartwright MNSs - Answers System associated with glycophorin A and B Kidd - Answers Antibodies in the system often fall below detectable levels and are associated with delayed Transfusion reaction Vel - Answers Antigen of high incidence; its antibody can cause hemolytic transfusion reaction Xga - Answers Antigen has higher frequency in females Sda Antigens - Answers Antibody to this antigen demonstrates weak mixed field reaction Chido/Rodgers - Answers Antibodies are sensitive to enzymes and have high-titter low-avidity characteristics Kell - Answers System associated with chronic granulomatosis disease Duffy - Answers System associated with risitance to malaria K-positive donor red cells were mistakenly transfused to a recipient with anti-K. The patient's posttransfusion blood sample has a positive direct antiglobulin test with polyspecific antihuman globulin. The direct antiglobulin test is positive because anti-K is an __________ antibody that has sensitized the __________ cells in vivo. - Answers IgG, Donor's Which of the following antigens are derived from plasma rather tha constituting an integral part of the red cell membrane - Answers Le^a, Rg^a, Ch^a Which of the following is NOT a high- frequency antigen - Answers Js^a (20% frequency in black population and < 0.1 frequency in whites Which of the following antigens is poorly expressed on cord cells - Answers Le^b Which of the following phenotypes is homozygous (One allele) - Answers Fy(a-b+) What antigens are destroyed when treated with ficin - Answers Fy^b and M Which set of antibodies generally reacts at room temperature or below (cold antibodies) - Answers Anti-N, -P1, -Le^b What do the linked HLA genes on each chromosome constitute - Answers Haplotype (MHC genes that encode HLA antigens are inherited as haplotypes) A non-sector will most likely have which of the following phenotypes - Answers Le(a+b-) Which of the following is the source of HLA-compatible platelets - Answers Siblings Which of the following antigens is located on glycophorine B - Answers S,s,U Which blood group system possesses the Js ^b and Kp^a antigens - Answers Kell Which of th following antibodies is commonly associated with delayed transfusion - Answers Anti-Jk^b Which phenotype is associated with a resistance to Plasmodium vivax? - Answers Fy(a-b-) Enzyme-treated reagent red cells used in antibody identification enhance anti-body reactions. Which of the following antibodies is not enhanced with the use of enzyme-treated red cells - Answers Anti-M Which of these antibodies are typically IgM? - Answers Anti-N, anti-Leb^b anti-P1 Which of the following reagents destroys the Kell system antigens - Answers PEG Which blood group system's antigens are associated with glycophorin A and glycophorin B - Answers MNs Which of the following antibodies is characteristically clinically insignificant - Answers Anti-Le^b Which of the following red cell phenotypes is associated with the McLeod phenotype - Answers Absence of Ku antigens