Exam Solution Manual for Blood Bank Chapter 10 Already Passed
Coughing, cyanosis, and difficulty breathing are symptoms of which of the transfusion reactions -
Answers TRALI
Reaction to donors HLA Ab to the granulocytes in the recipients - Answers TRALI
The use of only male donors as a source of plasma for transfusion is a method to reduce the risk of -
Answers TRALI
In a delayed hemolytic transfusion reaction, the DAT is typically - Answers Mixed-field Positive
Which of the transfusion reactions is associated with high fever, shock, hemoglobinuria, and DIC -
Answers Sepsis - Bacterial Contamination
A patient was identified as having cardiac insufficiency that needed a red blood cell transfusion. How
should the transfusion be administered - Answers at a slow rate in small volume aliquots. 4-6 hour
process
In what circumstance would a DAT be negative in the presence of a hemolytic process - Answers
1Bacterial contamination of the unit
2Medications that were administered with the unit
3Red blood cell unit transfused quickly through a leukocyte reduction filter
Which of the following is necessary to prevent an anaphylactic reaction due to a known IgA antibody in a
patient - Answers Red blood cell units should be washed
An anaphylactic transfusion reaction is caused by __________ antibodies - Answers anti-IgA
Long-term red blood cell transfusion can result in what of the conditions
Transfusion dependent - Answers Hemosiderosis
Posttransfusion purpura is caused by - Answers Platelet Antibodies
A hemolytic reaction to red blood cells can be caused by which of the following nonimmune
mechanisms - Answers -Incompatible intravenous solutions mixed with the unit, -Improper storage of
the unit, and -bacterial contamination of the unit
Which of the following transfusion reactions has the highest incidence - Answers Urticarial
What organ of the recipient's body is involved in a TRALI - Answers Lungs
, What component is indicated for patients who receive directed donations from immediate family
members to prevent graft-versus-host transfusion reactions - Answers Irradiated Red Blood Cells
Administration of whole blood to a patient with cardiac insufficiency could result in what type of
transfusion reaction - Answers TACO (Circulatory Overload )
Which blood product is recommended for transfusions to individuals with a history of febrile
nonhemolytic transfusion reactions - Answers Leukocyte-reduced Red Blood Cells
What is a common cause of febrile non hemolytic reaction? - Answers Recipient has HLA Ab to the
donors hla ag
Ten days after the transfusion of 2 units, a patient had a 2 g/dL drop in hemoglobin and was slightly
jaundiced. No evidence of bleeding was found. What tests would be helpful in determining whether the
patient is experiencing a delayed hemolytic transfusion reaction - Answers Perform an antibody screen
on the current posttransfustion sample
A 44-year-old woman has a hemoglobin level of 6.1 g/dL. White blood cell and platelet counts are within
normal levels. The patient is group O D-negative with a negative antibody screen. Crossmatches are
compatible. However, 15 minutes after the first transfusion is started, she experiences erythema and
hives. What type of transfusion reaction is occurring? - Answers Urticarial -Allergic reaction
A patient is observed to have a rise in temperature and chills during a transfusion. The transfusion is
stopped, and a posttransfusion blood sample is carefully drawn. On receipt of this postreaction sample,
the transfusion service should immediately - Answers Observe the color of the serum and perform a DAT
What are the top blood group systems have been implicated in transfusion reactions on the first
exposure to incompatible red blood cells - Answers ABO
What is the first thing you do when you receive a call that a patient is having a transfusion reaction -
Answers Stop the transfusion, keep line open with saline.
What pt are at risk for circulatory overload - Answers Patients over 70 and infants
Name three differences between an Acute vs a Delayed transfusion reaction - Answers -Acute signs
within 24 hours
-Delayed after 24 hours
-Acute usually due to ABO incompatibility
-Delayed usually due to IgG Ab
-Acute high severity than Delayed
List 5 common symptoms of an adverse transfusion reaction - Answers Fever/Chills, Pain,
Dyspnea/respiratory distress,Bleeding, Hypotension/Hypertension
Coughing, cyanosis, and difficulty breathing are symptoms of which of the transfusion reactions -
Answers TRALI
Reaction to donors HLA Ab to the granulocytes in the recipients - Answers TRALI
The use of only male donors as a source of plasma for transfusion is a method to reduce the risk of -
Answers TRALI
In a delayed hemolytic transfusion reaction, the DAT is typically - Answers Mixed-field Positive
Which of the transfusion reactions is associated with high fever, shock, hemoglobinuria, and DIC -
Answers Sepsis - Bacterial Contamination
A patient was identified as having cardiac insufficiency that needed a red blood cell transfusion. How
should the transfusion be administered - Answers at a slow rate in small volume aliquots. 4-6 hour
process
In what circumstance would a DAT be negative in the presence of a hemolytic process - Answers
1Bacterial contamination of the unit
2Medications that were administered with the unit
3Red blood cell unit transfused quickly through a leukocyte reduction filter
Which of the following is necessary to prevent an anaphylactic reaction due to a known IgA antibody in a
patient - Answers Red blood cell units should be washed
An anaphylactic transfusion reaction is caused by __________ antibodies - Answers anti-IgA
Long-term red blood cell transfusion can result in what of the conditions
Transfusion dependent - Answers Hemosiderosis
Posttransfusion purpura is caused by - Answers Platelet Antibodies
A hemolytic reaction to red blood cells can be caused by which of the following nonimmune
mechanisms - Answers -Incompatible intravenous solutions mixed with the unit, -Improper storage of
the unit, and -bacterial contamination of the unit
Which of the following transfusion reactions has the highest incidence - Answers Urticarial
What organ of the recipient's body is involved in a TRALI - Answers Lungs
, What component is indicated for patients who receive directed donations from immediate family
members to prevent graft-versus-host transfusion reactions - Answers Irradiated Red Blood Cells
Administration of whole blood to a patient with cardiac insufficiency could result in what type of
transfusion reaction - Answers TACO (Circulatory Overload )
Which blood product is recommended for transfusions to individuals with a history of febrile
nonhemolytic transfusion reactions - Answers Leukocyte-reduced Red Blood Cells
What is a common cause of febrile non hemolytic reaction? - Answers Recipient has HLA Ab to the
donors hla ag
Ten days after the transfusion of 2 units, a patient had a 2 g/dL drop in hemoglobin and was slightly
jaundiced. No evidence of bleeding was found. What tests would be helpful in determining whether the
patient is experiencing a delayed hemolytic transfusion reaction - Answers Perform an antibody screen
on the current posttransfustion sample
A 44-year-old woman has a hemoglobin level of 6.1 g/dL. White blood cell and platelet counts are within
normal levels. The patient is group O D-negative with a negative antibody screen. Crossmatches are
compatible. However, 15 minutes after the first transfusion is started, she experiences erythema and
hives. What type of transfusion reaction is occurring? - Answers Urticarial -Allergic reaction
A patient is observed to have a rise in temperature and chills during a transfusion. The transfusion is
stopped, and a posttransfusion blood sample is carefully drawn. On receipt of this postreaction sample,
the transfusion service should immediately - Answers Observe the color of the serum and perform a DAT
What are the top blood group systems have been implicated in transfusion reactions on the first
exposure to incompatible red blood cells - Answers ABO
What is the first thing you do when you receive a call that a patient is having a transfusion reaction -
Answers Stop the transfusion, keep line open with saline.
What pt are at risk for circulatory overload - Answers Patients over 70 and infants
Name three differences between an Acute vs a Delayed transfusion reaction - Answers -Acute signs
within 24 hours
-Delayed after 24 hours
-Acute usually due to ABO incompatibility
-Delayed usually due to IgG Ab
-Acute high severity than Delayed
List 5 common symptoms of an adverse transfusion reaction - Answers Fever/Chills, Pain,
Dyspnea/respiratory distress,Bleeding, Hypotension/Hypertension
