TESTBANK FOR PHARMACOTHERAPUTICS 4TH EDITION
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,TESTBANK FOR PHARMACOTHERAPUTICS 4TH EDITION
w w w
Chapter 1 Issues for the Practitioner in Drug Therapy
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MULTIPLE CHOICE w
1. Nurse practitioner prescriptive authority is regulated by:
w w w w w w
A. The National Council of State Boards of
w w w w w w
Nursing
w
B. The U.S. Drug Enforcement Administration
w w w w
C. The State Board of Nursing for each state
w w w w w w w
D. The State Board of Pharmacy
w w w w
ANS: w C PTS: w 1
2. Physician Assistant (PA) prescriptive authority is regulated by:
w w w w w w w
A. The National Council of State Boards of
w w w w w w
w Nursing
B. The U.S. Drug Enforcement Administration
w w w w
C. The State Board of Nursing
w w w w
D. The State Board of Medical Examiners
w w w w w
ANS: w D PTS: w 1
3. Clinical judgment in prescribing includes:
w w w w
A. Factoring in the cost to the patient of the medication prescribed
w w w w w w w w w w
B. Always prescribing the newest medication available for the disease
w w w w w w w w
process
w
C. Handing out drug samples to poor patients
w w w w w w
D. Prescribing all generic medications to cut costs
w w w w w w
ANS: w A PTS: w 1
4. Criteria for choosing an effective drug for a disorder include:
w w w w w w w w w
A. Asking the patient what drug they think would work best for them
w w w w w w w w w w w
B. Consulting nationally recognized guidelines for disease management
w w w w w w
C. Prescribing medications that are available as samples before writing a
w w w w w w w w w
prescription
w
D. Following U.S. Drug Enforcement Administration (DEA) guidelines for
w w w w w w w
prescribing
w
ANS: w B PTS: w 1
5. Nurse practitioner practice may thrive under health-care reform due to:
w w w w w w w w w
A. The demonstrated ability of nurse practitioners to control costs and improve
w w w w w w w w w w
patient outcomes
w w
B. The fact that nurse practitioners will be able to practice independently
w w w w w w w w w w
C. The fact that nurse practitioners will have full reimbursement under health-care
w w w w w w w w w w
reform
w
D. The ability to shift accountability for Medicaid to the state level
w w w w w w w w w w
ANS: w A PTS: w 1
,TESTBANK FOR PHARMACOTHERAPUTICS 4TH EDITION
w w w
Chapter 2.Pharmacokinetic Basis of Therapeutics and
w w w w w
Pharmacodynamic
w
MULTIPLE CHOICE w
1. A patient’s nutritional intake and lab work reflects hypoalbuminemia. This is critical
w w w w w w w w w w w
wto prescribing because:
w w
A. Distribution of drugs to target tissue may be affected w w w w w w w w
B. The solubility of the drug will not match the site of
w w w w w w w w w w
absorption
w
C. There will be less free drug available to generate an effect
w w w w w w w w w w
D. Drugs bound to albumin are readily excreted by the kidney
w w w w w w w w w
ANS: w A PTS: w 1
2. Drugs that have a significant first-pass effect:
w w w w w w
A. Must be given by the enteral (oral) route only
w w w w w w w w
B. Bypass the hepatic circulation w w w
C. Are rapidly metabolized by the liver and may have little if any desired
w w w w w w w w w w w w
action w
D. Are converted by the liver to more active and fat-soluble forms
w w w w w w w w w w
ANS: w C PTS: w 1
3. The route of excretion of a volatile drug will likely be:
w w w w w w w w w w
A. The kidneys w
B. The lungs w
C. The bile and feces w w w
D. The skin w
ANS: w B PTS: w 1
4. Medroxyprogesterone (Depo Provera) is prescribed IM to create a storage reservoir of w w w w w w w w w w w
wthe drug. Storage reservoirs:
w w w
A. Assure that the drug will reach its intended target
w w w w w w w w
tissue w
B. Are the reason for giving loading doses
w w w w w w
C. Increase the length of time a drug is available and
w w w w w w w w w
active w
D. Are most common in collagen tissues
w w w w w
ANS: w C PTS: w 1
5. The NP chooses to give cephalexin every 8 hours based on knowledge of the drug’s:
w w w w w w w w w w w w w w
A. Propensity to go to the target w w w w w
receptor w
B. Biological half-life w
C. Pharmacodynamics
D. Safety and side effects w w w
ANS: w B PTS: w 1
, TESTBANK FOR PHARMACOTHERAPUTICS 4TH EDITION
w w w
6. Azithromycin dosing requires the first day’s dose be twice those of the other 4 days of
w w w w w w w w w w w w w w w
wthe prescription. This is considered a loading dose. A loading dose:
w w w w w w w w w w
A. Rapidly achieves drug levels in the therapeutic
w w w w w w
w range
B. Requires four to five half-lives to attain
w w w w w w
C. Is influenced by renal function
w w w w
D. Is directly related to the drug circulating to the target
w w w w w w w w w
w tissues
ANS: w A PTS: w 1
7. The point in time on the drug concentration curve that indicates the first sign of a
w w w w w w w w w w w w w w w
therapeutic effect is the:
w w w w
A. Minimum adverse effect level w w w
B. Peak of action w w
C. Onset of action w w
D. Therapeutic range w
ANS: w C PTS: w 1
8. Phenytoin requires a trough level be drawn. Peak and trough levels are done:
w w w w w w w w w w w w
A. When the drug has a wide therapeutic range
w w w w w w w
B. When the drug will be administered for a short time only
w w w w w w w w w w
C. When there is a high correlation between the dose and saturation of receptor
w w w w w w w w w w w w
sitesw
D. To determine if a drug is in the therapeutic range
w w w w w w w w w
ANS: w D PTS: w 1
9. A laboratory result indicates the peak level for a drug is above the minimum
w w w w w w w w w w w w w
wtoxic concentration. This means that the:
w w w w w
A. Concentration will produce therapeutic effects w w w w
B. Concentration will produce an adverse w w w w
w response
C. Time between doses must be shortened
w w w w w
D. Duration of action of the drug is too long
w w w w w w w w
ANS: w B PTS: w 1
10. Drugs that are receptor agonists may demonstrate what property?
w w w w w w w w
A. Irreversible binding to the drug receptor site w w w w w w
B. Up-regulation with chronic use w w w
C. Desensitization or down-regulation with continuous use w w w w w
D. Inverse relationship between drug concentration and drug
w w w w w w
w action
ANS: w C PTS: w 1
11. Drugs that are receptor antagonists, such as beta blockers, may cause:
w w w w w w w w w w
A. Down-regulation of the drug receptor w w w w
B. An exaggerated response if abruptly discontinued
w w w w w
C. Partial blockade of the effects of agonist drugs
w w w w w w w
D. An exaggerated response to competitive drug
w w w w w
w agonists
w w w
,TESTBANK FOR PHARMACOTHERAPUTICS 4TH EDITION
w w w
Chapter 1 Issues for the Practitioner in Drug Therapy
w w w w w w w w
MULTIPLE CHOICE w
1. Nurse practitioner prescriptive authority is regulated by:
w w w w w w
A. The National Council of State Boards of
w w w w w w
Nursing
w
B. The U.S. Drug Enforcement Administration
w w w w
C. The State Board of Nursing for each state
w w w w w w w
D. The State Board of Pharmacy
w w w w
ANS: w C PTS: w 1
2. Physician Assistant (PA) prescriptive authority is regulated by:
w w w w w w w
A. The National Council of State Boards of
w w w w w w
w Nursing
B. The U.S. Drug Enforcement Administration
w w w w
C. The State Board of Nursing
w w w w
D. The State Board of Medical Examiners
w w w w w
ANS: w D PTS: w 1
3. Clinical judgment in prescribing includes:
w w w w
A. Factoring in the cost to the patient of the medication prescribed
w w w w w w w w w w
B. Always prescribing the newest medication available for the disease
w w w w w w w w
process
w
C. Handing out drug samples to poor patients
w w w w w w
D. Prescribing all generic medications to cut costs
w w w w w w
ANS: w A PTS: w 1
4. Criteria for choosing an effective drug for a disorder include:
w w w w w w w w w
A. Asking the patient what drug they think would work best for them
w w w w w w w w w w w
B. Consulting nationally recognized guidelines for disease management
w w w w w w
C. Prescribing medications that are available as samples before writing a
w w w w w w w w w
prescription
w
D. Following U.S. Drug Enforcement Administration (DEA) guidelines for
w w w w w w w
prescribing
w
ANS: w B PTS: w 1
5. Nurse practitioner practice may thrive under health-care reform due to:
w w w w w w w w w
A. The demonstrated ability of nurse practitioners to control costs and improve
w w w w w w w w w w
patient outcomes
w w
B. The fact that nurse practitioners will be able to practice independently
w w w w w w w w w w
C. The fact that nurse practitioners will have full reimbursement under health-care
w w w w w w w w w w
reform
w
D. The ability to shift accountability for Medicaid to the state level
w w w w w w w w w w
ANS: w A PTS: w 1
,TESTBANK FOR PHARMACOTHERAPUTICS 4TH EDITION
w w w
Chapter 2.Pharmacokinetic Basis of Therapeutics and
w w w w w
Pharmacodynamic
w
MULTIPLE CHOICE w
1. A patient’s nutritional intake and lab work reflects hypoalbuminemia. This is critical
w w w w w w w w w w w
wto prescribing because:
w w
A. Distribution of drugs to target tissue may be affected w w w w w w w w
B. The solubility of the drug will not match the site of
w w w w w w w w w w
absorption
w
C. There will be less free drug available to generate an effect
w w w w w w w w w w
D. Drugs bound to albumin are readily excreted by the kidney
w w w w w w w w w
ANS: w A PTS: w 1
2. Drugs that have a significant first-pass effect:
w w w w w w
A. Must be given by the enteral (oral) route only
w w w w w w w w
B. Bypass the hepatic circulation w w w
C. Are rapidly metabolized by the liver and may have little if any desired
w w w w w w w w w w w w
action w
D. Are converted by the liver to more active and fat-soluble forms
w w w w w w w w w w
ANS: w C PTS: w 1
3. The route of excretion of a volatile drug will likely be:
w w w w w w w w w w
A. The kidneys w
B. The lungs w
C. The bile and feces w w w
D. The skin w
ANS: w B PTS: w 1
4. Medroxyprogesterone (Depo Provera) is prescribed IM to create a storage reservoir of w w w w w w w w w w w
wthe drug. Storage reservoirs:
w w w
A. Assure that the drug will reach its intended target
w w w w w w w w
tissue w
B. Are the reason for giving loading doses
w w w w w w
C. Increase the length of time a drug is available and
w w w w w w w w w
active w
D. Are most common in collagen tissues
w w w w w
ANS: w C PTS: w 1
5. The NP chooses to give cephalexin every 8 hours based on knowledge of the drug’s:
w w w w w w w w w w w w w w
A. Propensity to go to the target w w w w w
receptor w
B. Biological half-life w
C. Pharmacodynamics
D. Safety and side effects w w w
ANS: w B PTS: w 1
, TESTBANK FOR PHARMACOTHERAPUTICS 4TH EDITION
w w w
6. Azithromycin dosing requires the first day’s dose be twice those of the other 4 days of
w w w w w w w w w w w w w w w
wthe prescription. This is considered a loading dose. A loading dose:
w w w w w w w w w w
A. Rapidly achieves drug levels in the therapeutic
w w w w w w
w range
B. Requires four to five half-lives to attain
w w w w w w
C. Is influenced by renal function
w w w w
D. Is directly related to the drug circulating to the target
w w w w w w w w w
w tissues
ANS: w A PTS: w 1
7. The point in time on the drug concentration curve that indicates the first sign of a
w w w w w w w w w w w w w w w
therapeutic effect is the:
w w w w
A. Minimum adverse effect level w w w
B. Peak of action w w
C. Onset of action w w
D. Therapeutic range w
ANS: w C PTS: w 1
8. Phenytoin requires a trough level be drawn. Peak and trough levels are done:
w w w w w w w w w w w w
A. When the drug has a wide therapeutic range
w w w w w w w
B. When the drug will be administered for a short time only
w w w w w w w w w w
C. When there is a high correlation between the dose and saturation of receptor
w w w w w w w w w w w w
sitesw
D. To determine if a drug is in the therapeutic range
w w w w w w w w w
ANS: w D PTS: w 1
9. A laboratory result indicates the peak level for a drug is above the minimum
w w w w w w w w w w w w w
wtoxic concentration. This means that the:
w w w w w
A. Concentration will produce therapeutic effects w w w w
B. Concentration will produce an adverse w w w w
w response
C. Time between doses must be shortened
w w w w w
D. Duration of action of the drug is too long
w w w w w w w w
ANS: w B PTS: w 1
10. Drugs that are receptor agonists may demonstrate what property?
w w w w w w w w
A. Irreversible binding to the drug receptor site w w w w w w
B. Up-regulation with chronic use w w w
C. Desensitization or down-regulation with continuous use w w w w w
D. Inverse relationship between drug concentration and drug
w w w w w w
w action
ANS: w C PTS: w 1
11. Drugs that are receptor antagonists, such as beta blockers, may cause:
w w w w w w w w w w
A. Down-regulation of the drug receptor w w w w
B. An exaggerated response if abruptly discontinued
w w w w w
C. Partial blockade of the effects of agonist drugs
w w w w w w w
D. An exaggerated response to competitive drug
w w w w w
w agonists
