NU 545 CH 7 Exam With Complete Solution
Latest Update
Cathelicidins - ANSWER Family of antimicrobial peptides that in humans has one
member.
Defensins - ANSWER antimicrobial peptides that inhibit microbial growth
Mannose-binding lectin (MBL) - ANSWER soluble acute-phase protein in the blood that
binds to mannose residues on pathogen surfaces and, when bound, activates the
complement system by the lectin pathway
Resistin-like molecule beta - ANSWER Found in intestinal goblet cells, where it appears
to protect against helminth infections.
Antimicrobial lectins - ANS Lectin (carbohydrate binding protein) family with activity
against Gram+ bacteria; C-type lectins
Bactericidal/permeability-inducing protein (BPI) - ANS Stored in neutrophils and
intestinal epithelium. Reacts with lipopolysaccharide on the surface of gram-negative
bacteria, resulting in bacterial lysis.
inflammatory response - ANS nonspecific defense reaction to tissue damage caused by
injury or infection
acute inflammatory response - ANSWER series of cellular changes that bring blood to
the site of an injury or infection.
1)vasodilation
2)increased vascular permeability
, 3)diapedesis
Diapedesis - ANSWER Passage of white blood cells through intact vessel walls into
tissue
3 plasma protein systems - ANSWER complement, clotting, kinin
proenzyme - ANSWER an inactive precursor of an enzyme
complement system - ANS A group of about 30 blood proteins that may amplify the
inflammatory response, enhance phagocytosis, or directly lyse extracellular pathogens.
3 pathways of complement system - ANS classical, alternative, lectin
classical pathway - ANS activated by antibodies bound to antigen, which interact with
complement system. Begins with activation of complement protein C1
lectin pathway - ANS mannose-binding lectin binds to pathogen surface. It is antibody
independent.
Anaphylaxotoxins - ANSWER they cause rapid mast cell de granulation and histamine
release, leading to vasodilation and increased vascular permeability. They appear early
in the course of an inflammatory response, locally around the site of inflammation.
alternative pathway - ANSWER it is engaged by gram negative bacteria and fungal cell
wall polysaccharides
complement cascade - ANSWER a specific sequence of events, usually involving
antigen-antibody complexes, where each successive component of the complement
system is activated in turn
antigen-antibody complex - ANSWER the complex that results from an antibody binding
Latest Update
Cathelicidins - ANSWER Family of antimicrobial peptides that in humans has one
member.
Defensins - ANSWER antimicrobial peptides that inhibit microbial growth
Mannose-binding lectin (MBL) - ANSWER soluble acute-phase protein in the blood that
binds to mannose residues on pathogen surfaces and, when bound, activates the
complement system by the lectin pathway
Resistin-like molecule beta - ANSWER Found in intestinal goblet cells, where it appears
to protect against helminth infections.
Antimicrobial lectins - ANS Lectin (carbohydrate binding protein) family with activity
against Gram+ bacteria; C-type lectins
Bactericidal/permeability-inducing protein (BPI) - ANS Stored in neutrophils and
intestinal epithelium. Reacts with lipopolysaccharide on the surface of gram-negative
bacteria, resulting in bacterial lysis.
inflammatory response - ANS nonspecific defense reaction to tissue damage caused by
injury or infection
acute inflammatory response - ANSWER series of cellular changes that bring blood to
the site of an injury or infection.
1)vasodilation
2)increased vascular permeability
, 3)diapedesis
Diapedesis - ANSWER Passage of white blood cells through intact vessel walls into
tissue
3 plasma protein systems - ANSWER complement, clotting, kinin
proenzyme - ANSWER an inactive precursor of an enzyme
complement system - ANS A group of about 30 blood proteins that may amplify the
inflammatory response, enhance phagocytosis, or directly lyse extracellular pathogens.
3 pathways of complement system - ANS classical, alternative, lectin
classical pathway - ANS activated by antibodies bound to antigen, which interact with
complement system. Begins with activation of complement protein C1
lectin pathway - ANS mannose-binding lectin binds to pathogen surface. It is antibody
independent.
Anaphylaxotoxins - ANSWER they cause rapid mast cell de granulation and histamine
release, leading to vasodilation and increased vascular permeability. They appear early
in the course of an inflammatory response, locally around the site of inflammation.
alternative pathway - ANSWER it is engaged by gram negative bacteria and fungal cell
wall polysaccharides
complement cascade - ANSWER a specific sequence of events, usually involving
antigen-antibody complexes, where each successive component of the complement
system is activated in turn
antigen-antibody complex - ANSWER the complex that results from an antibody binding
