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NUR 111 Exam 4 Questions And Accurate Answers A+ Graded

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NUR 111 Exam 4 Questions And Accurate
Answers A+ Graded


Inflammation - ANSWER Is a localized reaction intended to neutralize, control or
eliminate an offending agent.



Inflammatory Response - ANSWER Inflammation is a localized reaction intended to
neutralize, control or eliminate an offending agent.

Nonspecific response to injured or dead cells

Eliminates invading pathogens

Allows for tissue repair

Occurs in response to infection or injury

Infection is one way to get inflammation but it is not the only way

Can be acute or chronic

That offending agent may be the persons own body

Not specific

A protecting mechanism that responds to injured or dead cells

Usually occurs in healthy tissue adjacent to the dead cells



Stages of Inflammation - ANSWER 1st stage: Vascular response

Blood vessel response



2nd stage: Cellular Response

White blood cells



Reparative phase

,They all happen very close together



Vascular Response - ANSWER Usually localized to the area of injury but can be systemic

Momentary vasoconstriction then lots of Vasodilation

Increased permeability of vasculature

Facilitated passage of blood and cells through wall of blood vessel

Increased concentration of blood

Because of the vasoconstriction and permeability

Clotting

Because platelets run to the site that help clot off injury to stop the bleeding



Cellular Response - ANSWER Leukocytes build up at site

Because of the increased permeability of the blood vessels

Cytokines induce endothelial cells to bind to leukocytes

Hormones, cytokines that signal the brain that there is an injury

WBCs leak from capillary into tissue

Infection fighting WBC's are present in tissue

WBC's phagocytose invading organisms



Exudate - ANSWER You have exudate associated with inflammation

When exudate begins to contain bacteria and bacterial debris it then becomes puss and
is an indication of a bacterial infection and becomes part of your excaudate

Moves into injured area after inflammatory event as part of the cellular response

Contains

Proteins

Fluid

,Lymphocytes

Monocytes

Macrophages

Granulocytes

Healthy exudate - ANSWER The whole point of it if it is health is to:

Eliminate pathogen

Remove dead tissue debris

Secrete cytokines

Begin healing

Reparative Phase - ANSWER Glucose and oxygen travel to site needing repair

Regeneration depends on the type of cells

Regeneration

Labile

They multiply constantly

So they are relatively easy to regenerate

Ex. Skin cells

Permanent

Does not regenerate

Ex. Neurons

Stable

Regenerate sometimes if there is injury

Takes longer because they do not multiply constantly

Ex. Kidney or liver cells

Replacement

Replacing the tissue that was damaged



Acute Inflammatory Response - ANSWER Tissue injury/exposure and the release of

, chemical mediators



Vasodilation and increased blood flow



Swelling and retraction of activated endothelial cells



Increased vascular permeability and leakage of small plasma proteins



"Walling

off"



Movement of immune response cells to the site of injury



Exudate formation



Movement of glucose and oxygen to the site needing repair



Release of

chemical repair

factors

from activated

endothelial

cells



Chemical Mediators - ANSWER Histamine and Kinins



Histamine - ANSWER Pro-inflammatory

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