(Basic and Clinical Pharmacology, 14th Edition – Katzung & Trevor test bank A+: 2026).
Test Bank – Chapter 1
Basic and Clinical Pharmacology, 14th Edition – Katzung & Trevor
Chapter 1: Introduction – The Nature of Drugs & Drug Development & Regulation
Multiple Choice Questions
1. A nurse administers iodine for a CT scan, chemotherapy for cancer, and MMR
vaccine for routine immunization. Which branch of pharmacology describes these
actions?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Feedback: Pharmacotherapeutics deals with the use of drugs to treat, prevent, and
diagnose disease. Pharmacodynamics is how drugs affect the body;
pharmacokinetics is how the body processes drugs; pharmacoeconomics considers
costs of therapy.
2. A physician orders IM morphine every 4 hours as needed for pain. Morphine has high
abuse potential. Its classification is:
A) Schedule I
B) Schedule II
C) Schedule III
D) Schedule IV
Feedback: Schedule II drugs have a high potential for abuse but have accepted
medical uses. Schedule I drugs have no accepted medical use. Schedule III–IV
drugs have lower abuse potential.
3. In phase III drug evaluation studies, what is the nurse’s responsibility?
A) Working with animals
B) Choosing study participants
C) Monitoring patients for adverse effects
D) Conducting research on drug effectiveness
Feedback: Nurses monitor patients closely during phase III, documenting adverse
Page 1 of 825 3/23/2026, 4:16:49 PM
, (Basic and Clinical Pharmacology, 14th Edition – Katzung & Trevor test bank A+: 2026).
effects. Animal testing is preclinical, and participant selection is usually phase II.
Nurses do not independently conduct drug research.
4. Which concept is considered when substituting generic drugs for brand-name drugs?
A) Bioavailability
B) Critical concentration
C) Distribution
D) Half-life
Feedback: Bioavailability is the fraction of a dose that reaches systemic circulation. It
may differ between brand and generic drugs due to excipients. Distribution and
half-life are generally unchanged.
5. When assessing a patient’s home medications, the priority question is:
A) Do you take any generic medications?
B) Are any orphan drugs?
C) Are these safe during pregnancy?
D) Do you take any over-the-counter medications?
Feedback: OTC medications may be overlooked by patients but can cause
interactions or adverse effects. Other questions require specialized knowledge.
6. After completing a pharmacology course, the nurse will know:
A) Everything for safe medication administration
B) Current therapy for 5 years without further learning
C) General drug information; consult a drug guide for specifics
D) Drug actions for all classifications
Feedback: Nurses must continually update knowledge as pharmacology evolves;
drug guides provide current, specific information.
7. Regarding Pregnancy Category B drugs, the nurse informs the patient:
A) Adequate human studies show no risk
B) Animal studies show no risk, but human studies are lacking
C) Animal studies show fetal harm, no human data
D) Human risk exists, but benefits may outweigh risks
Feedback: Category B indicates safety in animal studies; human data are
insufficient.
8. Which patient comment shows understanding of OTC drugs?
A) OTC drugs are completely safe
B) OTC drugs are untested by FDA
Page 2 of 825 3/23/2026, 4:16:49 PM
, (Basic and Clinical Pharmacology, 14th Edition – Katzung & Trevor test bank A+: 2026).
C) OTC drugs differ from prescription drugs and cost less
D) OTC drugs can cause serious harm if misused
Feedback: OTC medications are safe when used correctly but can still cause harm.
Education on proper use is essential.
9. The best source of drug information for nurses is:
A) Drug Facts and Comparisons
B) Nurse’s drug guide
C) Drug package insert
D) Physician’s Drug Reference (PDR)
Feedback: Nurse drug guides provide nursing implications, teaching points, and
practical information.
10. A multidose bottle has a soiled label but readable drug name. The nurse should:
A) Discard the bottle and obtain a new one
B) Create a new label
C) Ask another nurse to verify
D) Administer if name is visible
Feedback: A full label contains crucial information: concentration, expiration, instructions.
Partial labels are unsafe.
11. Which aspects of pharmacology do nurses study? (Select all that apply)
A) Chemical pharmacology
B) Molecular pharmacology
C) Impact of drugs on the body
D) Body’s response to drugs
E) Adverse and anticipated effects
Feedback: Nursing pharmacology focuses on drug effects and patient response, not
molecular or chemical aspects.
12. Unexpected or negative drug effects are called:
A) Teratogenic effects
B) Toxic effects
C) Adverse effects
D) Therapeutic effects
13. After administering medication, the nurse should assess for:
A) Drug effects
Page 3 of 825 3/23/2026, 4:16:49 PM
, (Basic and Clinical Pharmacology, 14th Edition – Katzung & Trevor test bank A+: 2026).
B) Allergies
C) Pregnancy
D) Preexisting conditions
14. If a drug guide is 4 years old, the nurse should:
A) Find a more recent reference source
B) Use it if the drug is listed
C) Ask another nurse
D) Verify with pharmacist
15. For discharge medication teaching, the nurse should provide:
A) Personal contact info
B) Thorough medication teaching
C) OTC medications for side effects
D) Sample-size medications
16. All medications undergo rigorous scientific testing by:
A) FDA
B) DEA
C) CDC
D) JCAHO
17. Why can women of reproductive age often not participate in Phase I studies?
A) Drugs pose unknown risks to ova/fetus
B) Men are stronger
C) Women are more prone to adverse effects
D) Drugs affect women differently
18. A doctor cannot prescribe a drug in preclinical testing because:
A) Paperwork is required
B) Companies may seek volunteers
C) Preclinical drugs are only tested in animals
D) Preclinical drugs are only tested in men
19. Unexpected adverse effects in Phase III studies should be explained: (Select all that
apply)
A) Companies underreport for profit
B) Effect is reported to FDA
Page 4 of 825 3/23/2026, 4:16:49 PM
, (Basic and Clinical Pharmacology, 14th Edition – Katzung & Trevor test bank A+: 2026).
C) Large clinical use may reveal new effects
D) Companies weigh benefits vs risks
E) Drug will not be recalled
Page 5 of 825 3/23/2026, 4:16:49 PM
Test Bank – Chapter 1
Basic and Clinical Pharmacology, 14th Edition – Katzung & Trevor
Chapter 1: Introduction – The Nature of Drugs & Drug Development & Regulation
Multiple Choice Questions
1. A nurse administers iodine for a CT scan, chemotherapy for cancer, and MMR
vaccine for routine immunization. Which branch of pharmacology describes these
actions?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Feedback: Pharmacotherapeutics deals with the use of drugs to treat, prevent, and
diagnose disease. Pharmacodynamics is how drugs affect the body;
pharmacokinetics is how the body processes drugs; pharmacoeconomics considers
costs of therapy.
2. A physician orders IM morphine every 4 hours as needed for pain. Morphine has high
abuse potential. Its classification is:
A) Schedule I
B) Schedule II
C) Schedule III
D) Schedule IV
Feedback: Schedule II drugs have a high potential for abuse but have accepted
medical uses. Schedule I drugs have no accepted medical use. Schedule III–IV
drugs have lower abuse potential.
3. In phase III drug evaluation studies, what is the nurse’s responsibility?
A) Working with animals
B) Choosing study participants
C) Monitoring patients for adverse effects
D) Conducting research on drug effectiveness
Feedback: Nurses monitor patients closely during phase III, documenting adverse
Page 1 of 825 3/23/2026, 4:16:49 PM
, (Basic and Clinical Pharmacology, 14th Edition – Katzung & Trevor test bank A+: 2026).
effects. Animal testing is preclinical, and participant selection is usually phase II.
Nurses do not independently conduct drug research.
4. Which concept is considered when substituting generic drugs for brand-name drugs?
A) Bioavailability
B) Critical concentration
C) Distribution
D) Half-life
Feedback: Bioavailability is the fraction of a dose that reaches systemic circulation. It
may differ between brand and generic drugs due to excipients. Distribution and
half-life are generally unchanged.
5. When assessing a patient’s home medications, the priority question is:
A) Do you take any generic medications?
B) Are any orphan drugs?
C) Are these safe during pregnancy?
D) Do you take any over-the-counter medications?
Feedback: OTC medications may be overlooked by patients but can cause
interactions or adverse effects. Other questions require specialized knowledge.
6. After completing a pharmacology course, the nurse will know:
A) Everything for safe medication administration
B) Current therapy for 5 years without further learning
C) General drug information; consult a drug guide for specifics
D) Drug actions for all classifications
Feedback: Nurses must continually update knowledge as pharmacology evolves;
drug guides provide current, specific information.
7. Regarding Pregnancy Category B drugs, the nurse informs the patient:
A) Adequate human studies show no risk
B) Animal studies show no risk, but human studies are lacking
C) Animal studies show fetal harm, no human data
D) Human risk exists, but benefits may outweigh risks
Feedback: Category B indicates safety in animal studies; human data are
insufficient.
8. Which patient comment shows understanding of OTC drugs?
A) OTC drugs are completely safe
B) OTC drugs are untested by FDA
Page 2 of 825 3/23/2026, 4:16:49 PM
, (Basic and Clinical Pharmacology, 14th Edition – Katzung & Trevor test bank A+: 2026).
C) OTC drugs differ from prescription drugs and cost less
D) OTC drugs can cause serious harm if misused
Feedback: OTC medications are safe when used correctly but can still cause harm.
Education on proper use is essential.
9. The best source of drug information for nurses is:
A) Drug Facts and Comparisons
B) Nurse’s drug guide
C) Drug package insert
D) Physician’s Drug Reference (PDR)
Feedback: Nurse drug guides provide nursing implications, teaching points, and
practical information.
10. A multidose bottle has a soiled label but readable drug name. The nurse should:
A) Discard the bottle and obtain a new one
B) Create a new label
C) Ask another nurse to verify
D) Administer if name is visible
Feedback: A full label contains crucial information: concentration, expiration, instructions.
Partial labels are unsafe.
11. Which aspects of pharmacology do nurses study? (Select all that apply)
A) Chemical pharmacology
B) Molecular pharmacology
C) Impact of drugs on the body
D) Body’s response to drugs
E) Adverse and anticipated effects
Feedback: Nursing pharmacology focuses on drug effects and patient response, not
molecular or chemical aspects.
12. Unexpected or negative drug effects are called:
A) Teratogenic effects
B) Toxic effects
C) Adverse effects
D) Therapeutic effects
13. After administering medication, the nurse should assess for:
A) Drug effects
Page 3 of 825 3/23/2026, 4:16:49 PM
, (Basic and Clinical Pharmacology, 14th Edition – Katzung & Trevor test bank A+: 2026).
B) Allergies
C) Pregnancy
D) Preexisting conditions
14. If a drug guide is 4 years old, the nurse should:
A) Find a more recent reference source
B) Use it if the drug is listed
C) Ask another nurse
D) Verify with pharmacist
15. For discharge medication teaching, the nurse should provide:
A) Personal contact info
B) Thorough medication teaching
C) OTC medications for side effects
D) Sample-size medications
16. All medications undergo rigorous scientific testing by:
A) FDA
B) DEA
C) CDC
D) JCAHO
17. Why can women of reproductive age often not participate in Phase I studies?
A) Drugs pose unknown risks to ova/fetus
B) Men are stronger
C) Women are more prone to adverse effects
D) Drugs affect women differently
18. A doctor cannot prescribe a drug in preclinical testing because:
A) Paperwork is required
B) Companies may seek volunteers
C) Preclinical drugs are only tested in animals
D) Preclinical drugs are only tested in men
19. Unexpected adverse effects in Phase III studies should be explained: (Select all that
apply)
A) Companies underreport for profit
B) Effect is reported to FDA
Page 4 of 825 3/23/2026, 4:16:49 PM
, (Basic and Clinical Pharmacology, 14th Edition – Katzung & Trevor test bank A+: 2026).
C) Large clinical use may reveal new effects
D) Companies weigh benefits vs risks
E) Drug will not be recalled
Page 5 of 825 3/23/2026, 4:16:49 PM
