MLT 106 Immunology WT1 68K Army/Navy Lab
Tech Questions And Answers
Immunity ANS process by which a host organism protects itself from external and internal agents
Self v Nonself
acquired (specific) immunity ANS formation of specific antibodies and response, provides "memory" for
previous encounters
Cellular Immunity ANS *CELLS ANTIGENS*
Cells:
Macs, T-Cells, Dendritic Cells
Cytokines (Lymphokines and monokines)
Chemokines
Cytokines (as part of cellular immunity) ANS *FLUID ANTIBODIES* soluble peptide messenger
Lymphokines - lymphocytes
Monokines - by monocytes and macrophages
Humoral Immunity ANS fluid components of immune system
Abs, Complements
Natural Immunity (Passive) ANS Mechanisms: physical, biochemical, mechanical, or combo
,response that is static w/ repeat exposure
Complement system
Physical Barriers ANS Skin
Mucous Membranes
Cilia
Cough reflex
Biochemical Barriers ANS Enzymes
FAs
Swear
Acid
Innate Cells ANS Phagocytic and NK
Major Phagocytic Cells ANS Polymorphonuclear: granulocytes
Mononuclear: monocytes in plasma and tissue
Complement System Roles ANS Opsonization & Phagocytosis
Lysis (cells, bac, enveloped virus)
Inflammation mediation
Secondary / Adaptive / Acquired / Specific Immunity ANS Major part and most specific
Antithetical antigen ANS Antigen that an antibody is made against
, B lymphocytes (B cells / Plasma Cells) ANS Develop in BM
Plasma Cell - activated B cell, makes Abs
exposure to antigen activates cell
T Cells ANS Born in BM
Develop in Thymus
Primary cell in Cell-Mediated Immunity
60-80% of circulating lymphocytes
T Helper Cell / CD4 ANS Activate MACs and suppressor
Help B-cells Ab production
MHC II -> recognition
Killer T Cells (CD8) ANS recognize MHC I
Cytotoxic T Cells
intracellular pathogens
secrete TNF and IFN
Lyse infected cells
Regulatory (suppressor) T cells ANS suppress T and B Cells to regulate response
Tech Questions And Answers
Immunity ANS process by which a host organism protects itself from external and internal agents
Self v Nonself
acquired (specific) immunity ANS formation of specific antibodies and response, provides "memory" for
previous encounters
Cellular Immunity ANS *CELLS ANTIGENS*
Cells:
Macs, T-Cells, Dendritic Cells
Cytokines (Lymphokines and monokines)
Chemokines
Cytokines (as part of cellular immunity) ANS *FLUID ANTIBODIES* soluble peptide messenger
Lymphokines - lymphocytes
Monokines - by monocytes and macrophages
Humoral Immunity ANS fluid components of immune system
Abs, Complements
Natural Immunity (Passive) ANS Mechanisms: physical, biochemical, mechanical, or combo
,response that is static w/ repeat exposure
Complement system
Physical Barriers ANS Skin
Mucous Membranes
Cilia
Cough reflex
Biochemical Barriers ANS Enzymes
FAs
Swear
Acid
Innate Cells ANS Phagocytic and NK
Major Phagocytic Cells ANS Polymorphonuclear: granulocytes
Mononuclear: monocytes in plasma and tissue
Complement System Roles ANS Opsonization & Phagocytosis
Lysis (cells, bac, enveloped virus)
Inflammation mediation
Secondary / Adaptive / Acquired / Specific Immunity ANS Major part and most specific
Antithetical antigen ANS Antigen that an antibody is made against
, B lymphocytes (B cells / Plasma Cells) ANS Develop in BM
Plasma Cell - activated B cell, makes Abs
exposure to antigen activates cell
T Cells ANS Born in BM
Develop in Thymus
Primary cell in Cell-Mediated Immunity
60-80% of circulating lymphocytes
T Helper Cell / CD4 ANS Activate MACs and suppressor
Help B-cells Ab production
MHC II -> recognition
Killer T Cells (CD8) ANS recognize MHC I
Cytotoxic T Cells
intracellular pathogens
secrete TNF and IFN
Lyse infected cells
Regulatory (suppressor) T cells ANS suppress T and B Cells to regulate response
